scholarly journals CLINICAL PROFILES OF GLAUCOMATOUS PATIENTS WITH HIGH- AND LOW-TENSION OPTIC DISC HEMORRHAGES: A COMPARATIVE STUDY

2020 ◽  
Author(s):  
Izabela Almeida ◽  
Diego Torres Dias ◽  
Paula Azevedo Alhadeff ◽  
Flavio Siqueira Santos Lopes ◽  
Carolina P B Gracitelli ◽  
...  
Keyword(s):  
Optic Disc ◽  
Normal Tension Glaucoma ◽  
Cross Sectional Study ◽  
Mean Deviation ◽  
Cross Sectional ◽  
Disc Hemorrhage ◽  
Vascular Dysregulation ◽  
Median Split ◽  
Clinical Profiles ◽  
Low Tension

Background/Aims: Optic disc hemorrhage (DH) is an important glaucoma risk factor, and occurs in a wide intraocular pressure (IOP) range. We sought to characterize distinct clinical subtypes of patients with high- (HTDH) and low-tension DHs (LTDH). Methods: In this cross-sectional study, treated glaucomatous patients with DHs from two Glaucoma Services were consecutively enrolled. Disc photographs were evaluated for the presence of DH by two glaucoma specialists. After inclusion, patients were classified on HTDH (IOP≥16mmHg) and LTDH (IOP<16mmHg; median split). Clinical and ocular data from the time of DH detection were compared between groups. Results: One hundred thirty-three DH patients were included (LTDH=66 eyes; HTDH=67 eyes). Patients with LTDH were more often women than those with HTDH (77% vs 42%; p=0.030). There was also a trend for a higher prevalence of Asian descendants (24% vs 9%; p=0.058) and symptoms suggestive of vascular dysregulation (34% vs 14%; p=0.057) in LTDH patients. Eyes with LTDH also had worse visual field (VF) mean deviation index (p=0.037), higher prevalence of normal-tension glaucoma (NTG) diagnosis (46% vs 17%; p<0.001) and tended to have thinner central corneas (p=0.066). Conclusion: Patients developing DHs with treated IOPs in the low teens seem to more frequently fit in a profile represented by women, NTG diagnosis and greater VF loss. The presence of symptoms suggestive of vascular dysregulation and race also seem to differ between these two clinical subtypes. A closer optic disc surveillance is recommended for patients with the LTDH subtype, as they may develop DHs despite seemingly well-controlled IOP.

scholarly journals Optic disc hemorrhage in nonglaucomatous eyes: A cross-sectional study with average 8-year follow-up

PLoS ONE ◽  
2020 ◽  
Vol 15 (8) ◽  
pp. e0237796
Author(s):  
Yeo-Yang Koh ◽  
Chi-Chun Lai ◽  
Henry S. L. Chen ◽  
Ling Yeung ◽  
Wan-Chen Ku ◽  
...  
Keyword(s):  
Optic Disc ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Disc Hemorrhage

Association Between Platelet Function and Disc Hemorrhage in Patients With Normal-Tension Glaucoma: A Prospective Cross-Sectional Study

2015 ◽  
Vol 160 (6) ◽  
pp. 1191-1199.e1 ◽  
Author(s):  
Seong Hee Shim ◽  
Joon Mo Kim ◽  
Hee-Yeon Woo ◽  
Ko Un Shin ◽  
Jae Woong Koh ◽  
...  
Keyword(s):  
Platelet Function ◽  
Normal Tension Glaucoma ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Disc Hemorrhage

scholarly journals Optic Disc Hemorrhage after Phacoemulsification in Patients with Glaucoma

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Karine D. Bojikian ◽  
Daniel B. Moore ◽  
Philip P. Chen ◽  
Mark A. Slabaugh
Keyword(s):  
Optic Disc ◽  
Pressure Fluctuations ◽  
Cross Sectional Study ◽  
Clinic Visit ◽  
Optic Disk ◽  
Slit Lamp ◽  
Sectional Study ◽  
Cross Sectional ◽  
Disc Hemorrhage ◽  
Slit Lamp Biomicroscopy

Background. Optic disk hemorrhage is known to be a risk factor for glaucoma progression. Cataract surgery by phacoemulsification results in large intraocular pressure fluctuations. We aim to investigate whether phacoemulsification is associated with optic disc hemorrhage in patients with glaucoma. Methods. This is a retrospective review of consecutive university clinic based glaucoma patients undergoing phacoemulsification alone, with at least 3 visits in the year before and at least 5 visits in the year following phacoemulsification. The presence of optic disk hemorrhage was evaluated with slit lamp biomicroscopy at each clinic visit prior to and following phacoemulsification. Results. We evaluated 158 eyes of 158 subjects; 15 (9.5%) had ODH noted at least once during the 2-year study period. Four eyes had ODH identified on postoperative day 1, for a cross-sectional prevalence of 2.5%. Fourteen ODH episodes were noted preoperatively versus 12 episodes postoperatively (P=0.68). Aspirin use was associated with ODH (P=0.015). Conclusions. Our cross-sectional study found a prevalence of ODH immediately after CE that was similar to other published rates, and our longitudinal study did not find an increase in ODH in the year after phacoemulsification when compared to the year prior to surgery.

scholarly journals Comparitive study between normal tension glaucoma and primary open-angle glaucoma

2021 ◽  
Vol 7 (3) ◽  
pp. 562-567
Author(s):  
Sowmya Shree B V ◽  
Bharathi N ◽  
Shwetha Kumari C ◽  
Ranjitha C Sadananda ◽  
Madhura M Khanapur
Keyword(s):  
Open Angle Glaucoma ◽  
Visual Fields ◽  
Normal Tension Glaucoma ◽  
Cross Sectional Study ◽  
Mean Deviation ◽  
Cross Sectional ◽  
Neuroretinal Rim ◽  
Significant Difference ◽  
Independent Risk Factors ◽  
Work Up

The study is conducted to determine the functional and structural differences between NTG and POAG, to assess the rate of conversion of NTG into POAG and its early intervention. It is a hospital based prospective, cross-sectional study of 56 NTG and 56 POAG patients. History was taken and comprehensive ophthalmic examination with glaucoma work up was done.Majority of the patients belonged to the age group between 51 and 60 years i.e. 48.2% in NTG and 62.5% in POAG. Majority of the NTG patients i.e. 33 (58.9%) were females while 41(73.2%) were males in POAG. 40% of NTG patients had systemic association like bronchial asthma, diabetes, hypertension, ischemic heart disease and migraine. There was no significant difference in CDR between two groups. Inferior & temporal neuroretinal rim thinning was more common in NTG. While bipolar thinning & superior rim thinning was more common in POAG. There is significantly more thinning of RNFL in POAG than NTG. The mean deviation (MD) & pattern standard deviation (PSD) in visual fields between NTG & POAG showed no significant difference. Whereas the field loss was near centre of fixation in NTG group compared to POAG which was diffuse. These differences between NTG and POAG suggest that the pathogenesis of NTG includes IOP and IOP independent risk factors, while IOP is the main risk factor in POAG. The parameters assessed determine the risk and progression of NTG to POAG.

Malaria among migrants in a university hospital in Colombia during 2018: A case series

2020 ◽  
pp. 004947552098130
Author(s):  
Fabián R Carreño-Almánzar ◽  
Adán Coronado-Galán ◽  
Sonia A Cala-Gómez ◽  
Agustín Vega-Vera
Keyword(s):  
Latin American ◽  
Previous History ◽  
Case Series ◽  
Cross Sectional Study ◽  
Imported Malaria ◽  
University Hospital ◽  
Sectional Study ◽  
Cross Sectional ◽  
History Of ◽  
Clinical Profiles

Imported malaria has increased in Colombia since 2015 and has been attributed to migrants coming from Venezuela. We present a series of malaria cases, nested in a retrospective cross-sectional study between 2017 and 2018, aimed at calculating the prevalence of medical diseases among immigrants in a University Hospital in Colombia. Among 154 immigrants admitted for medical causes between 2017 and 2018, 8 were diagnosed with malaria, all due to Plasmodium vivax. Of these, seven had uncomplicated malaria, five had a previous history of malaria, one was critically ill, but none died. We highlight that, similar to other case series of imported malaria, Latin American migrants were young, with similar clinical profiles, having a low proportion of severe cases, and P. vivax was the most frequent cause.

scholarly journals Clinical Profiles and Types of Senile Cataract Patients: Experience of 30 Cases in Bangladesh

2019 ◽  
Vol 6 (1) ◽  
pp. 38-41
Author(s):  
Shamima Sultana ◽  
AQM Omar Sharif ◽  
Inamur Rahman Choudhury ◽  
MM Ehsanul Haque ◽  
Wahida Begum
Keyword(s):  
Cross Sectional Study ◽  
Senile Cataract ◽  
Cross Sectional ◽  
Data Collection Sheet ◽  
Study Population ◽  
Computer Based ◽  
Clinical Profiles ◽  
Patients Experience ◽  
Cataract Patients ◽  
Grade Iii

Background: Senile cataract can be expressed with different clinical presentation. Objective: The purpose of the present study was to find out the clinical profiles of senile cataract patients. Methodology: This cross-sectional study was conducted at National Institute of Ophthalmology, Dhaka, Bangladesh from January 1999 to December 2000 for a period of two (02) years. Patients with senile cataract were selected for study. The details clinical profiles of the study population were recorded like types, grades of cataract and visual acuity. Data were collected on pre-designed data collection sheet, compiled and appropriate statistical analysis was done using computer based software. Result: A total number of 60 eyes of cataract patients were recruited for this study. The mean age with the standard deviation was 58.8±6.055 years. Majority of the patients were suffering from total cataract that is nuclear plus cortical plus posterior subcapsular variety which was 31(51.7%) eyes of cataract patients. Majority of the patients were grade III (amber) type of nuclear sclerosis which was 26(43.3%) eyes of cataract patients. Most of the patients were presented with PL which was 32(53.3%) eyes of cataract patients. Conclusion: In conclusion majority of the patients are suffering from total cataract with grade III (amber) type of nuclear sclerosis. Journal of Current and Advance Medical Research 2019;6(1):38-41

Visual field defects and myopic macular degeneration in Singapore adults with high myopia

2021 ◽  
pp. bjophthalmol-2020-318674
Author(s):  
Carla Lanca ◽  
Chen Hsin Sun ◽  
Rachel Chong ◽  
Yee Ling Wong ◽  
Monisha Esther Nongpiur ◽  
...  
Keyword(s):  
Visual Field ◽  
Macular Degeneration ◽  
High Myopia ◽  
Cross Sectional Study ◽  
Visual Field Defects ◽  
Mean Deviation ◽  
Cross Sectional ◽  
Sensitivity Loss ◽  
Fundus Photographs ◽  
Generalised Estimating Equations

AimsTo characterise the association between visual field (VF) defects and myopic macular degeneration (MMD) in highly myopic adults without glaucoma.MethodsParticipants (n=106; 181 eyes) with high myopia (HM; spherical equivalent ≤−5.0 D or axial length (AL) ≥26 mm), after excluding glaucoma and glaucoma suspects, from the Singapore Epidemiology of Eye Diseases-HM study were included in this cross-sectional study. Humphrey VF (central 24–2 threshold), cup-disc ratio (CDR) and intraocular pressure (IOP) measurements were performed. Mean deviation (MD) and pattern SD (PSD), VF defects (normal or abnormal; p<0.05 in ≥3 non-edge contiguous locations) and pattern (eg, generalised sensitivity loss) were analysed. MMD presence was diagnosed from fundus photographs. Generalised estimating equations were used for analysing factors (MD, PSD, VF defects, CDR and IOP) associated with MMD.ResultsMean age was 55.4±9.9 years and 51.9% were women (AL=26.7±1.1 mm). MMD eyes had lower MD (−3.8±2.9 dB vs −1.1±1.4 dB) and higher PSD (2.8±1.7 dB vs 1.7±0.6 dB). A higher percentage of MMD eyes (n=48) had abnormal VF (62.5% vs 28.6%; p<0.001) compared with no MMD (n=133 eyes). VF pattern in MMD eyes was significantly different from eyes without MMD (p=0.001) with greater generalised sensitivity loss (53.3% vs 10.5%) and arcuate defects (16.7% vs 10.5%). In multivariate analyses, MD (OR=1.52) and PSD (OR=1.67) were significantly (p=0.003) associated with MMD, but VF defects were not associated with MMD.ConclusionHighly myopic adults with MMD may have VF loss when compared with highly myopic patients without MMD even in adults without glaucoma.

Clinical Profiles of Glaucomatous Patients with High- and Low-tension Optic Disc Hemorrhages

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Izabela N. F. Almeida ◽  
Diego Torres Dias ◽  
Paula Azevedo Alhadeff ◽  
Flavio Siqueira Santos Lopes ◽  
Augusto Paranhos ◽  
...  
Keyword(s):  
Optic Disc ◽  
Clinical Profiles ◽  
Low Tension

Clinical relevance of protruded retinal layers in minimum rim width measurement of the optic nerve head

2018 ◽  
Vol 103 (10) ◽  
pp. 1401-1405
Author(s):  
Lucas A Torres ◽  
Faisal Jarrar ◽  
Glen P Sharpe ◽  
Donna M Hutchison ◽  
Eduardo Ferracioli-Oda ◽  
...  
Keyword(s):  
Optic Nerve ◽  
Diagnostic Accuracy ◽  
Optic Nerve Head ◽  
Cross Sectional Study ◽  
Retinal Nerve Fibre Layer ◽  
Mean Deviation ◽  
Cross Sectional ◽  
Retinal Layers ◽  
Rnfl Thickness ◽  
Oct Imaging

Background/aimsOptical coherence tomography (OCT) imaging of the optic nerve head minimum rim width (MRW) has recently been shown to sometimes contain components besides extended retinal nerve fibre layer (RNFL). This study was conducted to determine whether excluding these components, termed protruded retinal layers (PRLs), from MRW increases diagnostic accuracy for detecting glaucoma.MethodsIn this cross-sectional study, we included 123 patients with glaucoma and 123 normal age-similar controls with OCT imaging of the optic nerve head (24 radial scans) and RNFL (circle scan). When present, PRLs were manually segmented, and adjusted MRW measurements were computed. We compared diagnostic accuracy of adjusted versus unadjusted MRW measurement. We also determined whether adjusted MRW correlates better with RNFL thickness compared with unadjusted MRW.ResultsThe median (IQR) visual field mean deviation of patients and controls was −4.4 (−10.3 to −2.1) dB and 0.0 (−0.6 to 0.8) dB, respectively. In the 5904 individual B-scans, PRLs were identified less frequently in patients (448, 7.6%) compared with controls (728, 12.3%; p<0.01) and were present most frequently in the temporal sector of both groups. Areas under the receiver operating characteristic curves and sensitivity values at 95% specificity indicated that PRL adjustment did not improve diagnostic accuracy of MRW, globally or temporally. Furthermore, adjusting MRW for PRL did not improve its correlation with RNFL thickness in either group.ConclusionWhile layers besides the RNFL are sometimes included in OCT measurements of MRW, subtracting these layers does not impact clinical utility.

Sign in / Sign up

Export Citation Format

Share Document