scholarly journals Predictors of symptomatic laboratory-confirmed SARS-COV-2 reinfection

2020 ◽  
Author(s):  
EFREN MURILLO-ZAMORA ◽  
CARLOS M HERNANDEZ-SUAREZ ◽  
AGUSTIN LUGO-RADILLO ◽  
FELIPE AGUILAR-SOLLANO ◽  
OLIVER MENDOZA-CANO
Keyword(s):  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Healthcare Workers ◽  
Primary Disease ◽  
Older Subjects ◽  
Reduced Risk ◽  
Overall Risk

Objective: To identify factors predicting symptomatic laboratory-positive SARS-COV-2 reinfection. Method: We conducted a nationwide retrospective cohort study and data from 99,993 confirmed cases of COVID-19 were analyzed. Results: The overall risk of reinfection (28 or more elapsed days between both episodes onset) was 0.21%, and older subjects and those with mild primary disease were at reduced risk of reinfection. Healthcare workers and immunosuppressed or renal patients had at greater risk of SARS-COV-2 reinfection. Conclusions: If replicated in other populations, these results may be useful to prioritize efforts focusing on the reduction of SARS-COV-2 spread and the related burden.

scholarly journals Symptomatic SARS-COV-2 reinfection: healthcare workers and immunosuppressed individuals at high risk

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Efrén Murillo-Zamora ◽  
Xóchitl Trujillo ◽  
Miguel Huerta ◽  
Mónica Ríos-Silva ◽  
Felipe Aguilar-Sollano ◽  
...  
Keyword(s):  
Public Health ◽  
Cohort Study ◽  
Retrospective Cohort ◽  
Healthcare Workers ◽  
Health Policies ◽  
Incidence Density ◽  
Public Health Policies ◽  
Factors Associated ◽  
Older Subjects ◽  
Reduced Risk

Abstract Background Knowledge regarding factors predicting the SARS-COV-2 reinfection risk is scarce and it has major implications in public health policies. We aimed to identify factors associated with the risk of symptomatic SARS-COV-2 reinfection. Methods We conducted a nationwide retrospective cohort study and 99,993 confirmed cases of COVID-19 were analyzed. Results The overall risk of reinfection (28 or more elapsed days between both episodes onset) was 0.21% (incidence density, 2.5 reinfections per 100,000 person-days) and older subjects and those with the mild primary disease were at reduced risk of the event. Healthcare workers and immunosuppressed or renal patients had at greater risk of SARS-COV-2 reinfection. Conclusions If replicated in other populations, these results may be useful to prioritize efforts focusing on the reduction of SARS-COV-2 spread and the related burden.

scholarly journals Sociodemographic risk factors for COVID-19 infection among Massachusetts healthcare workers: a retrospective cohort study

2021 ◽  
pp. 1-23
Author(s):  
Fan-Yun Lan ◽  
Robert Filler ◽  
Soni Mathew ◽  
Jane Buley ◽  
Eirini Iliaki ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cohort Study ◽  
Healthcare System ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Healthcare Workers ◽  
Occupational Risk Factors ◽  
Frontline Workers ◽  
Factors Associated ◽  
Occupational Risks

Abstract Objective: To better understand COVID-19 transmission among healthcare workers (HCW), we investigated occupational and non-occupational risk factors associated with cumulative COVID-19 incidence among a Massachusetts HCW cohort. Design, setting, and participants: The retrospective cohort study included adult HCWs in a single healthcare system from March 9 to June 3, 2020. Methods: Participants’ SARS-CoV-2 nasopharyngeal RT-PCR results and demographics were de-identified and extracted from an established occupational health, COVID-19 database at the healthcare system. HCWs from each particular job grouping had been categorized into frontline/non-frontline workers. Incidence rate ratio (IRR) and odds ratio were used to compare subgroups after excluding HCWs involved in early infection clusters before universal masking. A sensitivity analysis was performed comparing jobs with the greatest potential occupational risks with others. Results: 152 out of 5177 (2.94%) HCWs were diagnosed with COVID-19. Affected HCWs resided in areas with higher community attack rates (median: 1755.2 vs. 1412.4 cases per 100,000, P<0.001)(multivariate-adjusted IRR: 1.89, 95%CI: 1.03–3.44 comparing 5th to 1st quintile of community rates). After multivariate adjustment, African Americans and Hispanics had higher incidence than non-Hispanic white HCWs (IRR: 2.78, 95%CI: 1.78–4.33; and IRR: 2.41, 95%CI: 1.42–4.07, respectively). After adjusting for race and residential rates, frontline HCWs had a higher IRR (1.73, 95%CI: 1.16–2.54) compared to non-frontline HCWs overall, but not within specific job categories, nor when comparing the highest risk jobs to others. Conclusions: After universal masking was instituted, the strongest risk factors associated with HCWs’ COVID-19 infection were residential community infection rate and race.

scholarly journals A reduced risk of stroke with lithium exposure in bipolar disorder: a population-based retrospective cohort study

2015 ◽  
Vol 17 (7) ◽  
pp. 705-714 ◽  
Author(s):  
Chen-Chia Lan ◽  
Chia-Chien Liu ◽  
Ching-Heng Lin ◽  
Tzuo-Yun Lan ◽  
Melvin G McInnis ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Population Based ◽  
Reduced Risk

scholarly journals Risk Factors of Healthcare Workers With Coronavirus Disease 2019: A Retrospective Cohort Study in a Designated Hospital of Wuhan in China

2020 ◽  
Vol 71 (16) ◽  
pp. 2218-2221 ◽  
Author(s):  
Li Ran ◽  
Xuyu Chen ◽  
Ying Wang ◽  
Wenwen Wu ◽  
Ling Zhang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cohort Study ◽  
High Risk ◽  
Hand Hygiene ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Healthcare Workers ◽  
Respiratory Illness ◽  
Acute Respiratory Illness ◽  
Duty Hours

Abstract Coronavirus Disease 2019 (COVID-19), which originated in Wuhan, China, has caused many healthcare workers (HCWs) to be infected. Seventy-two HCWs manifested with acute respiratory illness were retrospectively enrolled to analyze the risk factors. The high-risk department, longer duty hours, and suboptimal hand hygiene after contacting with patients were linked to COVID-19.

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