scholarly journals Automatic detection of pituitary microadenoma from magnetic resonance imaging using deep learning algorithms

2021 ◽  
Author(s):  
Qingling Li ◽  
Yanhua Zhu ◽  
Minglin Chen ◽  
Ruomi Guo ◽  
Qingyong Hu ◽  
...  
Keyword(s):  
Deep Learning ◽  
Diagnostic Accuracy ◽  
Network Models ◽  
Clinical Workflow ◽  
Neural Network Models ◽  
Test Dataset ◽  
Cad System ◽  
Pituitary Microadenoma ◽  
Primary Health ◽  
Primary Health Care Institutions

Pituitary microadenoma (PM) is often difficult to detect by MR imaging alone. We employed a computer-aided PM diagnosis (PM-CAD) system based on deep learning to assist radiologists in clinical workflow. We enrolled 1,228 participants and stratified into 3 non-overlapping cohorts for training, validation and testing purposes. Our PM-CAD system outperformed 6 existing established convolutional neural network models for detection of PM. In test dataset, diagnostic accuracy of PM-CAD system was comparable to radiologists with > 10 years of professional expertise (94% versus 95%). The diagnostic accuracy in internal and external dataset was 94% and 90%, respectively. Importantly, PM-CAD system detected the presence of PM that had been previously misdiagnosed by radiologists. This is the first report showing that PM-CAD system is a viable tool for detecting PM. Our results suggest that PM-CAD system is applicable to radiology departments, especially in primary health care institutions.

scholarly journals Development and Validation of a Deep Learning Algorithm to Automatic Detection of Pituitary Microadenoma From MRI

2021 ◽  
Vol 8 ◽  
Author(s):  
Qingling Li ◽  
Yanhua Zhu ◽  
Minglin Chen ◽  
Ruomi Guo ◽  
Qingyong Hu ◽  
...  
Keyword(s):  
Deep Learning ◽  
Diagnostic Accuracy ◽  
Roc Curve ◽  
Predictive Value ◽  
Computer Aided Diagnosis ◽  
Validation Dataset ◽  
Cad System ◽  
Pituitary Microadenoma ◽  
Computer Aided ◽  
Aided Diagnosis

Background: It is often difficult to diagnose pituitary microadenoma (PM) by MRI alone, due to its relatively small size, variable anatomical structure, complex clinical symptoms, and signs among individuals. We develop and validate a deep learning -based system to diagnose PM from MRI.Methods: A total of 11,935 infertility participants were initially recruited for this project. After applying the exclusion criteria, 1,520 participants (556 PM patients and 964 controls subjects) were included for further stratified into 3 non-overlapping cohorts. The data used for the training set were derived from a retrospective study, and in the validation dataset, prospective temporal and geographical validation set were adopted. A total of 780 participants were used for training, 195 participants for testing, and 545 participants were used to validate the diagnosis performance. The PM-computer-aided diagnosis (PM-CAD) system consists of two parts: pituitary region detection and PM diagnosis. The diagnosis performance of the PM-CAD system was measured using the receiver operating characteristics (ROC) curve and area under the ROC curve (AUC), calibration curve, accuracy, sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and F1-score.Results: Pituitary microadenoma-computer-aided diagnosis system showed 94.36% diagnostic accuracy and 98.13% AUC score in the testing dataset. We confirm the robustness and generalization of our PM-CAD system, the diagnostic accuracy in the internal dataset was 96.50% and in the external dataset was 92.26 and 92.36%, the AUC was 95.5, 94.7, and 93.7%, respectively. In human-computer competition, the diagnosis performance of our PM-CAD system was comparable to radiologists with >10 years of professional expertise (diagnosis accuracy of 94.0% vs. 95.0%, AUC of 95.6% vs. 95.0%). For the misdiagnosis cases from radiologists, our system showed a 100% accurate diagnosis. A browser-based software was designed to assist the PM diagnosis.Conclusions: This is the first report showing that the PM-CAD system is a viable tool for detecting PM. Our results suggest that the PM-CAD system is applicable to radiology departments, especially in primary health care institutions.

scholarly journals Automatic detection of pituitary microadenoma from magnetic resonance imaging using deep learning algorithms

2020 ◽  
Author(s):  
Qingling Li ◽  
Yanhua Zhu ◽  
Minglin Chen ◽  
Ruomi Guo ◽  
Hao Liu ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Diagnostic Accuracy ◽  
Mr Images ◽  
Training Set ◽  
Cad System ◽  
Pituitary Microadenoma ◽  
Diagnosis Accuracy ◽  
Validation Set ◽  
Primary Health Care Institutions ◽  
Aided Diagnosis

Abstract The risks of misdiagnosed pituitary microadenoma is high. We designed a convolutional neural network (CNN) based computer-aided diagnosis (CAD) system to retrospectively diagnose patients with pituitary microadenoma. A total 5,540 pituitary magnetic resonance (MR) images from 1,108 participants were recruited. MRI images were randomly stratified into non-overlapping cohorts (training set, validation set and test set) to establish five different CNN models. The best CNN model is the ResNet with a diagnostic accuracy of 94%, which outperforms the diagnosis accuracy of our radiologists (64%-85%). The accuracy of our CAD system is further confirmed in additional MR datasets. The diagnostic accuracy of our ResNet model is comparable to the proficiency of a radiologist with 5-10 years’ experience. In summary, this is the first report showing that the CAD system is a viable tool for diagnosing pituitary microadenoma. CAD system is applicable to radiology departments, especially in primary health care institutions.

Deep learning and complex network theory based analysis on socialized manufacturing resources utilisations and an application case study

2021 ◽  
pp. 1063293X2110031
Author(s):  
Maolin Yang ◽  
Auwal H Abubakar ◽  
Pingyu Jiang
Keyword(s):  
Deep Learning ◽  
Complex Network ◽  
Network Models ◽  
Neural Network Models ◽  
Complex Network Theory ◽  
New Type ◽  
Manufacturing Resource ◽  
Manufacturing Resources ◽  
Resource Characteristics

Social manufacturing is characterized by its capability of utilizing socialized manufacturing resources to achieve value adding. Recently, a new type of social manufacturing pattern emerges and shows potential for core factories to improve their limited manufacturing capabilities by utilizing the resources from outside socialized manufacturing resource communities. However, the core factories need to analyze the resource characteristics of the socialized resource communities before making operation plans, and this is challenging due to the unaffiliated and self-driven characteristics of the resource providers in socialized resource communities. In this paper, a deep learning and complex network based approach is established to address this challenge by using socialized designer community for demonstration. Firstly, convolutional neural network models are trained to identify the design resource characteristics of each socialized designer in designer community according to the interaction texts posted by the socialized designer on internet platforms. During the process, an iterative dataset labelling method is established to reduce the time cost for training set labelling. Secondly, complex networks are used to model the design resource characteristics of the community according to the resource characteristics of all the socialized designers in the community. Two real communities from RepRap 3D printer project are used as case study.

Feature extraction-based image steganalysis using deep learning

2021 ◽  
pp. 188-198
Keyword(s):  
Neural Network ◽  
Deep Learning ◽  
Convolutional Neural Network ◽  
Secure Communication ◽  
Information Technologies ◽  
Network Models ◽  
Error Rates ◽  
Multimedia Data ◽  
Secret Message ◽  
Neural Network Models

The innovations in advanced information technologies has led to rapid delivery and sharing of multimedia data like images and videos. The digital steganography offers ability to secure communication and imperative for internet. The image steganography is essential to preserve confidential information of security applications. The secret image is embedded within pixels. The embedding of secret message is done by applied with S-UNIWARD and WOW steganography. Hidden messages are reveled using steganalysis. The exploration of research interests focused on conventional fields and recent technological fields of steganalysis. This paper devises Convolutional neural network models for steganalysis. Convolutional neural network (CNN) is one of the most frequently used deep learning techniques. The Convolutional neural network is used to extract spatio-temporal information or features and classification. We have compared steganalysis outcome with AlexNet and SRNeT with same dataset. The stegnalytic error rates are compared with different payloads.

scholarly journals Deep Network Guided Proof Search

10.29007/8mwc ◽  
2018 ◽  
Author(s):  
Sarah Loos ◽  
Geoffrey Irving ◽  
Christian Szegedy ◽  
Cezary Kaliszyk
Keyword(s):  
Deep Learning ◽  
Program Analysis ◽  
Network Models ◽  
Theorem Prover ◽  
Neural Network Models ◽  
Two Phase ◽  
First Order ◽  
Proof Search ◽  
System Verification ◽  
Theory Reasoning

Deep learning techniques lie at the heart of several significant AI advances in recent years including object recognition and detection, image captioning, machine translation, speech recognition and synthesis, and playing the game of Go.Automated first-order theorem provers can aid in the formalization and verification of mathematical theorems and play a crucial role in program analysis, theory reasoning, security, interpolation, and system verification.Here we suggest deep learning based guidance in the proof search of the theorem prover E. We train and compare several deep neural network models on the traces of existing ATP proofs of Mizar statements and use them to select processed clauses during proof search. We give experimental evidence that with a hybrid, two-phase approach, deep learning based guidance can significantly reduce the average number of proof search steps while increasing the number of theorems proved.Using a few proof guidance strategies that leverage deep neural networks, we have found first-order proofs of 7.36% of the first-order logic translations of the Mizar Mathematical Library theorems that did not previously have ATP generated proofs. This increases the ratio of statements in the corpus with ATP generated proofs from 56% to 59%.

SEALing Neural Network Models in Encrypted Deep Learning Accelerators

2021 ◽  
Author(s):  
Pengfei Zuo ◽  
Yu Hua ◽  
Ling Liang ◽  
Xinfeng Xie ◽  
Xing Hu ◽  
...  
Keyword(s):  
Neural Network ◽  
Deep Learning ◽  
Network Models ◽  
Neural Network Models

scholarly journals Guidelines and Benchmarks for Deployment of Deep Learning Models on Smartphones as Real-Time Apps

2019 ◽  
Vol 1 (1) ◽  
pp. 450-465 ◽  
Author(s):  
Abhishek Sehgal ◽  
Nasser Kehtarnavaz
Keyword(s):  
Deep Learning ◽  
Real Time ◽  
Open Source Software ◽  
Mobile Applications ◽  
Network Models ◽  
Software Tools ◽  
Learning Tools ◽  
Smartphone Apps ◽  
Learning Models ◽  
Neural Network Models

Deep learning solutions are being increasingly used in mobile applications. Although there are many open-source software tools for the development of deep learning solutions, there are no guidelines in one place in a unified manner for using these tools toward real-time deployment of these solutions on smartphones. From the variety of available deep learning tools, the most suited ones are used in this paper to enable real-time deployment of deep learning inference networks on smartphones. A uniform flow of implementation is devised for both Android and iOS smartphones. The advantage of using multi-threading to achieve or improve real-time throughputs is also showcased. A benchmarking framework consisting of accuracy, CPU/GPU consumption, and real-time throughput is considered for validation purposes. The developed deployment approach allows deep learning models to be turned into real-time smartphone apps with ease based on publicly available deep learning and smartphone software tools. This approach is applied to six popular or representative convolutional neural network models, and the validation results based on the benchmarking metrics are reported.

Beluga whale acoustic signal classification using deep learning neural network models

2020 ◽  
Vol 147 (3) ◽  
pp. 1834-1841 ◽  
Author(s):  
Ming Zhong ◽  
Manuel Castellote ◽  
Rahul Dodhia ◽  
Juan Lavista Ferres ◽  
Mandy Keogh ◽  
...  
Keyword(s):  
Neural Network ◽  
Deep Learning ◽  
Acoustic Signal ◽  
Network Models ◽  
Beluga Whale ◽  
Signal Classification ◽  
Neural Network Models ◽  
Deep Learning Neural Network

Application of Deep Learning for Characterization of Drivers’ Engagement in Secondary Tasks in In-Vehicle Systems

2020 ◽  
Vol 2674 (8) ◽  
pp. 429-440
Author(s):  
Osama A. Osman ◽  
Hesham Rakha
Keyword(s):  
Neural Network ◽  
Deep Learning ◽  
Time Series Data ◽  
Short Term Memory ◽  
Network Models ◽  
Sensor Technology ◽  
Series Data ◽  
Neural Network Models ◽  
Secondary Tasks ◽  
Driving Assistance

Distracted driving (i.e., engaging in secondary tasks) is an epidemic that threatens the lives of thousands every year. Data collected from vehicular sensor technologies and through connectivity provide comprehensive information that, if used to detect driver engagement in secondary tasks, could save thousands of lives and millions of dollars. This study investigates the possibility of achieving this goal using promising deep learning tools. Specifically, two deep neural network models (a multilayer perceptron neural network model and a long short-term memory networks [LSTMN] model) were developed to identify three secondary tasks: cellphone calling, cellphone texting, and conversation with adjacent passengers. The Second Strategic Highway Research Program Naturalistic Driving Study (SHRP 2 NDS) time series data, collected using vehicle sensor technology, were used to train and test the model. The results show excellent performance for the developed models, with a slight improvement for the LSTMN model, with overall classification accuracies ranging between 95 and 96%. Specifically, the models are able to identify the different types of secondary tasks with high accuracies of 100% for calling, 96%–97% for texting, 90%–91% for conversation, and 95%–96% for the normal driving. Based on this performance, the developed models improve on the results of a previous model developed by the author to classify the same three secondary tasks, which had an accuracy of 82%. The model is promising for use in in-vehicle driving assistance technology to report engagement in unlawful tasks or alert drivers to take over control in level 1 and 2 automated vehicles.

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