scholarly journals Potential Role of Red Palm Oil Supplemented Diet on Oxidative Stress Enzymes in Plasmodium Berghei Induced Malaria

2021 ◽  
Author(s):  
Temitope Daniel Adeleke ◽  
Olawale Abiodun Adejumobi ◽  
Franklin Folasele Akinola ◽  
Oluwatosin Abidemi Salau ◽  
Oyeronke Suebat Uthman-Izobo
Keyword(s):  
Oxidative Stress ◽  
Dietary Intake ◽  
Palm Oil ◽  
Plasmodium Berghei ◽  
Malaria Parasite ◽  
Red Palm Oil ◽  
Oxidative Stress Enzymes ◽  
Stress Enzymes ◽  
Group A ◽  
Group B

AbstractBackgroundMalaria parasites are very vulnerable to oxidative stress during the part of their life cycle when they inhabit the erythrocytes. Studies have shown that dietary intake of antioxidant plays a role in stabilizing oxidative stress.MethodsThe objective of this research work was to examine the antioxidative effect of red palm oil on Plasmodium berghei malaria induced oxidative stress. Sixty (60) mice were distributed into five groups. Group A served as the negative control (healthy mice with normal feed); group B as positive control (healthy mice fed with red palm oil without malaria parasite.while the other groups (C to E) served as the test groups. Group C served as group of healthy mice fed with red palm oil (pelletized), infected with malaria parasite without antimalaria drug. Group D served as group of healthy mice fed with red palm oil (pelletized), infected with malaria parasite and treated with amodiaquine. Group E served as group of healthy mice fed with normal feed, infected with malaria parasite and treated with amodiaquine. The parasitemia levels were estimated on days 1,4 and 5. The activity of oxidative stress enzymes biomarkers were determined spectrophotometrically.ResultGroup A showed a statistically significant increase in the activity of SOD (1.90 ± 0.16 units/mg protein), GST (1.68 ± 0.086 units/L) compared to group C, SOD (3.54 ± 0.83 units/mg protein), GST (2.12 ± 0.20 units/L). Group B showed a statistical significant decrease in the activities of SOD (3.22 ± 0.33 units/mg protein), Catalase (49.11 ± 2.35 µmol/min), GSH-R (31.50 ± 2.48 units/L) compared to group E, SOD (2.18 ± 0.39 units/mg protein), Catalase (44.07 ± 3.88 µmol/min), GSH-R (27.75 ± 1.64 units/L).ConclusionThe dietary intake of red palm oil helps to reduce free radical mediated injury to the tissue thus preventing oxidative stress induced by malaria or any other factors.

The Dinitrophenol and Potassium Iodate Influence on Hordeum Vulgare Seedlings Viability\

2018 ◽  
Vol 69 (8) ◽  
pp. 2160-2166
Author(s):  
Elena Todirascu Ciornea ◽  
Gabriela Dumitru ◽  
Ion Sandu
Keyword(s):  
Oxidative Stress ◽  
Hordeum Vulgare ◽  
Antioxidant Enzyme ◽  
Oxygen Radicals ◽  
Free Oxygen Radicals ◽  
Potassium Iodate ◽  
Free Oxygen ◽  
Oxidative Stress Enzymes ◽  
Stress Enzymes ◽  
Seeds Germination

The using of the pesticides of dinitrophenol type in agriculture has as consequence the major pollution of the environment, the plants taking these substances from the soil and once with these ones they reach in the human and animal organism where they product disequilibrium that are interpreted through the accumulation of free oxygen radicals with direct repercussions on the antioxidant enzyme�s synthesis intensification and on their activity�s increase. The apply of treatments on the barley seeds had significant effects regarding the seeds� germination, the young plants� growth, the oxidative stress enzymes� activity, but also regarding the content of photoassimilators and carotenoids pigments.

Effects of conjugated linoleic acid and curcumin on growth performance and oxidative stress enzymes in juvenile Pacific white shrimp ( Litopenaeus vannamei ) feed with aflatoxins

2019 ◽  
Vol 51 (3) ◽  
pp. 1051-1060
Author(s):  
Oscar Daniel García‐Pérez ◽  
Mireya Tapia‐Salazar ◽  
Martha G. Nieto‐López ◽  
Julio César Cruz‐Valdez ◽  
Maribel Maldonado-Muñiz ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Linoleic Acid ◽  
Growth Performance ◽  
Conjugated Linoleic Acid ◽  
Litopenaeus Vannamei ◽  
Pacific White Shrimp ◽  
White Shrimp ◽  
Oxidative Stress Enzymes ◽  
Stress Enzymes ◽  
And Oxidative Stress

Glycine and L-Arginine supplementation ameliorates gastro-duodenal toxicity in a rat model of NSAID (Diclofenac)-gastroenteropathy via inhibition of oxidative stress

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Akinleye Stephen Akinrinde ◽  
Halimot Olawalarami Hameed
Keyword(s):  
Oxidative Stress ◽  
Total Protein ◽  
Therapeutic Index ◽  
Control Treatment ◽  
Control Group ◽  
Protective Effects ◽  
Serum Total Protein ◽  
Significant Amelioration ◽  
Group A ◽  
Group B

Abstract Objectives This study examined the possible protective roles of exogenous glycine (Gly) and L-Arginine (l-Arg) against Diclofenac (DIC)-induced gastro-duodenal damage in rats. Methods Rats were divided into Group A (control), Group B (DIC group) and Groups C–F which were pre-treated for five days with Gly1 (250 mg/kg), Gly2 (500 mg/kg), l-Arg1 (200 mg/kg) and l-Arg2 (400 mg/kg), respectively, before co-treatment with DIC for another three days. Hematological, biochemical and histopathological analyses were then carried out. Results DIC produced significant (p<0.05) reduction in PCV (13.82%), Hb (46.58%), RBC (30.53%), serum total protein (32.72%), albumin (28.44%) and globulin (38.01%) along with significant (p<0.05) elevation of serum MPO activity (83.30%), when compared with control. In addition, DIC increased gastric H2O2 and MDA levels by 33.93 and 48.59%, respectively, while the duodenal levels of the same parameters increased by 19.43 and 85.56%, respectively. Moreover, SOD, GPx and GST activities in the DIC group were significantly (p<0.05) reduced in the stomach (21.12, 24.35 and 51.28%, respectively) and duodenum (30.59, 16.35 and 37.90%, respectively), compared to control. Treatment with Gly and l-Arg resulted in significant amelioration of the DIC-induced alterations although l-Arg produced better amelioration of RBC (29.78%), total protein (10.12%), albumin (9.93%) and MPO (65.01%), compared to the DIC group. The protective effects of both amino acids against oxidative stress parameters and histological lesions were largely similar. Conclusions The data from this study suggest that Gly or l-Arg prevented DIC-induced gastro-duodenal toxicity and might, therefore be useful in improving the therapeutic index of DIC.

Immunohistochemical detection of anti-oxidative stress enzymes in the dog brain

1997 ◽  
Vol 17 (4) ◽  
pp. 307-312 ◽  
Author(s):  
Wijit Kiatipattanasakul ◽  
Shin-ichiro Nakamura ◽  
Koji Kuroki ◽  
Hiroyuki Nakayama ◽  
Kunio Doi
Keyword(s):  
Oxidative Stress ◽  
Immunohistochemical Detection ◽  
Oxidative Stress Enzymes ◽  
Stress Enzymes ◽  
Dog Brain

scholarly journals Effect of Probiotic Supplementation on Oxidative Stress Enzymes and Mental Health of Athletes

2019 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Mahtab Noorifard ◽  
Arasb Dabbagh Moghaddam ◽  
Zatollah Asemi ◽  
Ramin Hamidi Farahani ◽  
Seyed Milad Mousavi Jazayeri ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Mental Health ◽  
Probiotic Supplementation ◽  
Oxidative Stress Enzymes ◽  
Stress Enzymes

scholarly journals Oxidative Stress Levels in Orthodontic Patients and Efficacy of Antioxidant Supplements in Combating Its Effects- A Randomized Clinical Study

2019 ◽  
Vol 9 (2) ◽  
pp. 29-34
Author(s):  
Sheetal Yamyar ◽  
Suchita Daokar
Keyword(s):  
Oxidative Stress ◽  
Free Radicals ◽  
Orthodontic Appliances ◽  
Randomized Clinical Study ◽  
Gingival Health ◽  
Orthodontic Patients ◽  
Group A ◽  
Antioxidant Supplements ◽  
Group B

Introduction: Orthodontic appliances are considered to be biocompatible although adverse effects attributed to release of nickel ion which are free radicals in oral cavity. These free radical produce damages both in cellular and extracellular components phospholipid membrane, proteins, mitochondrial and nuclear DNA leading to Oxidative stress which is normally counter balanced by the action antioxidant mechanisms. However in higher concentrations of free radicals resulting in cellular death and apoptosis Orthodontic appliances such as brackets, wire, resins has considered as potential allergen leading to release of free radicals. The study was conducted to determine and compare the role of oxidative stress and role of antioxidants in saliva of patients undergoing fixed orthodontic appliances therapy at different time intervals. Materials & Method: A double-blinded, parallel, randomized clinical study was designed consisting of 40 healthy participants, aged 15-30yrs. The samples were divided into two groups Group A without antioxidants supplements and Group B with antioxidants supplements. Salivary MDA levels and gingival health index was recorded at different time intervals from each group. Salivary Lipid peroxidation (Malondialdehyde) level was estimated using Thiobarbituric acid (TBA) method and gingival status was investigated using Silness & Loe gingival index. Intragroup and intergroup comparison was statistically analyzed using student’s paired T test. Result: Increased salivary MDA levels and mild to moderate amount of gingivitis is seen in both groups. This is more pronounced after 24 hours of appliance placement. Improvement in salivary MDA levels and gingival health status is observed during the course of treatment, In Group B the salivary MDA levels and gingival health index score reached below their pretreatment values. However even after a span of 3 months the levels remained higher to their base values in Group A. Conclusion: Improvement in salivary MDA levels and gingival health status is observed following antioxidant therapy during course of treatment, indicating combating nature of antioxidant supplements in orthodontic patients.

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