scholarly journals High-speed widefield handheld swept-source OCT angiography with a VCSEL light source

2021 ◽  
Author(s):  
Shuibin Ni ◽  
Xiang Wei ◽  
Ringo Ng ◽  
Susan Ostmo ◽  
Michael Chiang ◽  
...  
Keyword(s):  
High Speed ◽  
Neonatal Intensive Care ◽  
Motion Artifacts ◽  
Field Of View ◽  
Oct Angiography ◽  
Large Field ◽  
Incontinentia Pigmenti ◽  
Time Data ◽  
Hand Tremor ◽  
Swept Source

Optical coherence tomography (OCT) and OCT angiography (OCTA) enable noninvasive structural and angiographic imaging of the eye. Portable handheld OCT/OCTA systems are required for imaging patients in the supine position. Examples include infants in the neonatal intensive care unit (NICU) and operating room (OR). The speed of image acquisition plays a pivotal role in acquiring high quality OCT/OCTA images, particularly with the handheld system, since both the operator hand tremor and subject motion can cause significant motion artifacts. In addition, having a large field of view and the ability of real-time data visualization are critical elements in rapid disease screening, reducing imaging time, and detecting peripheral retinal pathologies. The arrangement of optical components is less flexible in the handheld system due to the limitation of size and weight. In this paper, we introduce a 400-kHz, 55-degree field of view handheld OCT/OCTA system that has overcome many technical challenges as a portable OCT system as well as a high-speed OCTA system. We demonstrate imaging premature infants with retinopathy of prematurity (ROP) in the NICU, and patients with incontinentia pigmenti (IP) in the OR using our handheld OCT system. Our design may have potential for improving the diagnosis of retinal diseases and help provide a practical guideline for designing a flexible and portable OCT system.

Doppler global velocimetry for 50 kHz, large field of view measurement of high-speed flows

2021 ◽  
Author(s):  
Ashley J. Saltzman ◽  
Kevin T. Lowe ◽  
Wing F. Ng
Keyword(s):  
High Speed ◽  
Field Of View ◽  
Large Field ◽  
High Speed Flows

scholarly journals NoRMCorre: An online algorithm for piecewise rigid motion correction of calcium imaging data

2017 ◽  
Author(s):  
Eftychios A. Pnevmatikakis ◽  
Andrea Giovannucci
Keyword(s):  
Calcium Imaging ◽  
Motion Correction ◽  
Rigid Motion ◽  
Motion Artifacts ◽  
Streaming Data ◽  
Field Of View ◽  
Large Field ◽  
Motion Field ◽  
Imaging Data ◽  
Two Photon

AbstractBackgroundMotion correction is a challenging pre-processing problem that arises early in the analysis pipeline of calcium imaging data sequences. The motion artifacts in two-photon microscopy recordings can be non-rigid, arising from the finite time of raster scanning and non-uniform deformations of the brain medium.New methodWe introduce an algorithm for fast Non-Rigid Motion Correction (NoRMCorre) based on template matching. NoRMCorre operates by splitting the field of view into overlapping spatial patches that are registered at a sub-pixel resolution for rigid translation against a continuously updated template. The estimated alignments are subsequently up-sampled to create a smooth motion field for each frame that can efficiently approximate non-rigid motion in a piecewise-rigid manner.Existing methodsExisting approaches either do not scale well in terms of computational performance or are targeted to motion artifacts arising from low speed scanning, whereas modern datasets with large field of view are more prone to non-rigid brain deformation issues.ResultsNoRMCorre can be run in an online mode resulting in comparable to or even faster than real time motion registration on streaming data. We evaluate the performance of the proposed method with simple yet intuitive metrics and compare against other non-rigid registration methods on two-photon calcium imaging datasets. Open source Matlab and Python code is also made available.ConclusionsThe proposed method and code provide valuable support to the community for solving large scale image registration problems in calcium imaging, especially when non-rigid deformations are present in the acquired data.

scholarly journals A Stereo-Vision System for Measuring the Ram Speed of Steam Hammers in an Environment with a Large Field of View and Strong Vibrations

Sensors ◽  
2019 ◽  
Vol 19 (5) ◽  
pp. 996 ◽  
Author(s):  
Ran Chen ◽  
Zhongwei Li ◽  
Kai Zhong ◽  
Xingjian Liu ◽  
Yonghui Wu ◽  
...  
Keyword(s):  
Stereo Vision ◽  
High Speed ◽  
Vision System ◽  
Calibration Method ◽  
Bundle Adjustment ◽  
Field Of View ◽  
Large Field ◽  
Practical Applications ◽  
Accuracy Of Measurements ◽  
Ram Speed

The ram speed of a steam hammer is an important parameter that directly affects the forming performance of forgers. This parameter must be monitored regularly in practical applications in industry. Because of the complex and dangerous industrial environment of forging equipment, non-contact measurement methods, such as stereo vision, might be optimal. However, in actual application, the field of view (FOV) required to measure the steam hammer is extremely large, with a value of 2–3 m, and heavy steam hammer, at high-speed, usually causes a strong vibration. These two factors combine to sacrifice the accuracy of measurements, and can even cause the failure of measurements. To solve these issues, a bundle-adjustment-principle-based system calibration method is proposed to realize high-accuracy calibration for a large FOV, which can obtain accurate calibration results when the calibration target is not precisely manufactured. To decrease the influence of strong vibration, a stationary world coordinate system was built, and the external parameters were recalibrated during the entire measurement process. The accuracy and effectiveness of the proposed technique were verified by an experiment to measure the ram speed of a counterblow steam hammer in a die forging device.

scholarly journals Diesel2p mesoscope with dual independent scan engines for flexible capture of dynamics in distributed neural circuitry

2020 ◽  
Author(s):  
Che-Hang Yu ◽  
Jeffrey N. Stirman ◽  
Yiyi Yu ◽  
Riichiro Hira ◽  
Spencer L. Smith
Keyword(s):  
Adaptive Optics ◽  
Calcium Imaging ◽  
High Speed ◽  
Optical Design ◽  
Neural Circuitry ◽  
Brain Regions ◽  
Field Of View ◽  
Large Field ◽  
Two Photon ◽  
Subcellular Resolution

AbstractImaging the activity of neurons that are widely distributed across brain regions deep in scattering tissue at high speed remains challenging. Here, we introduce an open-source system with Dual Independent Enhanced Scan Engines for Large Field-of-view Two-Photon imaging (Diesel2p). Combining novel optical design, adaptive optics, and temporal multiplexing, the system offers subcellular resolution over a large field-of-view (∼ 25 mm2) with independent scan engines. We demonstrate the flexibility and various use cases of this system for calcium imaging of neurons in the living brain.

scholarly journals High-speed and Large Field-of-view Imaging via X-ray Fly-scan Ptychography

2019 ◽  
Vol 25 (S2) ◽  
pp. 46-47
Author(s):  
Yi Jiang ◽  
Junjing Deng ◽  
Jeffrey A. Klug ◽  
Yudong Yao ◽  
Curt Preissner ◽  
...  
Keyword(s):  
High Speed ◽  
Field Of View ◽  
Large Field ◽  
X Ray

scholarly journals High resolution, high speed, long working distance, large field of view confocal fluorescence microscope

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Shaun Pacheco ◽  
Chengliang Wang ◽  
Monica K. Chawla ◽  
Minhkhoi Nguyen ◽  
Brend K. Baggett ◽  
...  
Keyword(s):  
High Resolution ◽  
High Speed ◽  
Fluorescence Microscope ◽  
Field Of View ◽  
Large Field ◽  
Confocal Fluorescence ◽  
Working Distance

High-speed, large field-of-view and deep imaging with an adaptive excitation source

2020 ◽  
Author(s):  
Bo Li ◽  
Chunyan Wu ◽  
Mengran Wang ◽  
Kriti Charan ◽  
Chris Xu
Keyword(s):  
High Speed ◽  
Field Of View ◽  
Excitation Source ◽  
Large Field ◽  
Deep Imaging

Design of Image Transmission System for Multi Channel Panchromatic TDICCD Camera with Large Field of View

2013 ◽  
Vol 380-384 ◽  
pp. 3758-3761 ◽  
Author(s):  
Long Xu Jin ◽  
Jin Li ◽  
Xian Peng Hao
Keyword(s):  
Time Delay ◽  
High Speed ◽  
Image Transmission ◽  
Transmission System ◽  
Field Of View ◽  
Large Field ◽  
Single Chip ◽  
Charge Coupled Devices ◽  
Data Volume ◽  
Ccd Image

In order to satisfy the transmission of mass data volume of on-board time delay integration charge coupled devices (TDICCD) image, a high speed image transmission system of space panchromatic TDICCD camera with a large field of view is designed in this paper. A 4-channel parallel high speed transmission system for 16-channel CCD image was designed. A high speed serializer TLK2711 is applied to send and receive multi channel TDICCD images. A single chip TLK2711 can processing 4 channels image. Experimental results show that the designed transmission system can reliably work. The designed transmission system can meet the application for space TDICCD camera with a large field of view.

scholarly journals High-speed and widefield handheld swept-source OCT angiography with a VCSEL light source

2021 ◽  
Author(s):  
Shuibin Ni ◽  
Xiang Wei ◽  
Ringo Ng ◽  
Susan Ostmo ◽  
Michael F. Chiang ◽  
...  
Keyword(s):  
Light Source ◽  
High Speed ◽  
Oct Angiography ◽  
Swept Source ◽  
Swept Source Oct ◽  
Swept Source Oct Angiography
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