scholarly journals Orthostatic intolerance in adults with long COVID was not associated with postural orthostatic tachycardia syndrome

2021 ◽  
Author(s):  
Ann Monaghan ◽  
Glenn Jennings ◽  
Feng Xue ◽  
Lisa Byrne ◽  
Eoin Duggan ◽  
...  
Keyword(s):  
Daily Living ◽  
Orthostatic Intolerance ◽  
Cross Sectional Study ◽  
Tilt Test ◽  
Postural Orthostatic Tachycardia Syndrome ◽  
Sectional Study ◽  
Cross Sectional ◽  
Minute Post ◽  
Head Up Tilt ◽  
Head Up Tilt Test

In this observational cross-sectional study, we investigated predictors of orthostatic intolerance (OI) in adults with long COVID. Participants underwent a 3-minute active stand (AS) with Finapres NOVA, followed by a 10-minute unmedicated 70-degree head-up tilt test. 85 participants were included (mean age 46 years, range 25-78; 74% women), of which 56 (66%) reported OI during AS (OIAS). OIAS seemed associated with female sex, more fatigue and depressive symptoms, and greater inability to perform activities of daily living (ADL), as well as a higher heart rate (HR) at the lowest systolic blood pressure (SBP) point before the 1st minute post-stand (mean HRnadir: 88 vs 75 bpm, P=0.004). In a regression model also including age, sex, fatigue, depression, ADL inability, and peak HR after the nadir SBP, HRnadir was the only OIAS predictor (OR=1.09, 95% CI: 1.01-1.18, P=0.027). 22 participants had initial (iOH) and 5 classical (cOH) orthostatic hypotension, but neither correlated with OIAS. 71 participants proceeded to tilt, of which 28 had OI during tilt (OItilt). Of the 53 who had a 10-minute tilt, 7 (13%) fulfilled hemodynamic postural orthostatic tachycardia syndrome (POTS) criteria, but 6 did not report OItilt. OIAS was associated with a higher initial HR on AS, which after 1 minute equalized with the non-OIAS group. Despite these initial orthostatic HR differences, POTS was infrequent and largely asymptomatic. ClinicalTrials.gov Identifier: NCT05027724 (retrospectively registered on August 30, 2021).

scholarly journals SHORT HEAD-UP TILT TEST

2012 ◽  
Vol 19 (04) ◽  
pp. 428-432
Author(s):  
HUMAIRA FAYYAZ KHAN ◽  
MUHAMMAD AMJAD HAMEED ◽  
KAMAL SALEEM ◽  
Ayyaz Ahmed ◽  
Nida Naeem
Keyword(s):  
Orthostatic Intolerance ◽  
Armed Forces ◽  
Cross Sectional Study ◽  
Tilt Test ◽  
Test Protocol ◽  
Cross Sectional ◽  
Stabilization Phase ◽  
Neurally Mediated Syncope ◽  
Head Up Tilt ◽  
Head Up Tilt Test

Objective: The aim of the present study was to evaluate the time to syncope in Nitroglycerine potentiated short Head-up tilt test.Study Design, Settings & Duration: This was a descriptive cross sectional study conducted in Armed Forces Institute of cardiology from May2006 to May, 2007. Patients and methods: A total number of 90 patients with orthostatic intolerance both male and female were studied.Head-up tilt test protocol consisted of a Stabilization phase which lasted for five minutes Passive tilt phase: Patients were tilted at 70̊ fororthostatic stress for 15 minutes. In case of no symptoms the test continued with the drug provocation phase which lasted for 15 minutes. Thepatients were administered 400μg of nitroglycerine sublingually in aerosol preparation. Development of symptoms were noted at 5, 10 and 15minutes. Results: A total number of 90 patients were examined during the study period. The tilt table test was classified as positive in 58.9 % ofpatients and was negative in 41.1%. The test was positive in five patients without the drug provocation (9.4%). The responses were classifiedas positive vasodepressor in 35.8%, 15.09% as mixed and cardioinhibitory 15.09% in patients of neurally mediated syncope. The total time todisplay of symptoms to positivity in HUTT was 17.89± 6.99. The mean time to syncope after the administration of nitroglycerine was 5.61± 4.17minutes. Conclusions: Our study concludes that the drug administered phase can be reduced to 12±3 minutes.

Tilt angles and positive response of head-up tilt test in children with orthostatic intolerance

2013 ◽  
Vol 25 (1) ◽  
pp. 76-80 ◽  
Author(s):  
Jing Lin ◽  
Yuli Wang ◽  
Todd Ochs ◽  
Chaoshu Tang ◽  
Junbao Du ◽  
...  
Keyword(s):  
Tilt Angle ◽  
Positive Response ◽  
Orthostatic Intolerance ◽  
Vasovagal Syncope ◽  
Tilt Test ◽  
Postural Orthostatic Tachycardia Syndrome ◽  
Appearance Time ◽  
Significant Difference ◽  
Head Up Tilt ◽  
Head Up Tilt Test

AbstractThis study aimed at examining three tilt angle-based positive responses and the time to positive response in a head-up tilt test for children with orthostatic intolerance, and the psychological fear experienced at the three angles during head-up tilt test. A total of 174 children, including 76 boys and 98 girls, aged from 4 to 18 years old (mean 11.3±2.8 years old), with unexplained syncope, were randomly divided into three groups, to undergo head-up tilt test at the angles of 60°, 70° and 80°, respectively. The diagnostic rates and times were analysed, and Wong–Baker face pain rating scale was used to access the children’s psychological fear. There were no significant differences in diagnostic rates of postural orthostatic tachycardia syndrome and vasovagal syncope at different tilt angles during the head-up tilt test (p>0.05). There was a significant difference, however, in the psychological fear at different tilt angles utilising the Kruskal–Wallis test (χ2=36.398, p<0.01). It was mildest at tilt angle 60° utilising the Kolmogorov–Smirnov test (p<0.01). A positive rank correlation was found between the psychological fear and the degree of tilt angle (rs=0.445, p<0.01). Positive response appearance time was 15.1±14.0 minutes at 60° for vasovagal syncope children. There was no significant difference in the time to positive response, at different tilt angles during the head-up tilt test for vasovagal syncope or for postural orthostatic tachycardia syndrome. Hence, it is suggested that a tilt angle of 60° and head-up tilt test time of 45 minutes should be suitable for children with vasovagal syncope.

scholarly journals Socioeconomic Factors and Health Status Disparities Associated with Difficulty in ADLs and IADLs among Long-Lived Populations in Brazil: A Cross-Sectional Study

2021 ◽  
Vol 58 ◽  
pp. 004695802110072
Author(s):  
Júlia Cristina Leite Nóbrega ◽  
Juliana Barbosa Medeiros ◽  
Tácila Thamires de Melo Santos ◽  
Saionara Açucena Vieira Alves ◽  
Javanna Lacerda Gomes da Silva Freitas ◽  
...  
Keyword(s):  
Health Status ◽  
Activities Of Daily Living ◽  
Socioeconomic Factors ◽  
Chronic Diseases ◽  
Daily Living ◽  
Female Gender ◽  
Well Being ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional

Objective: To evaluate the association between socioeconomic factors, health status, and Functional Capacity (FC) in the oldest senior citizens in a metropolis and a poor rural region of Brazil. Method: Cross-sectional study of 417 seniors aged ≥80 years, data collected through Brazil’s Health, Well-being and Aging survey. FC assessed by self-reporting of difficulties in Activities of Daily Living (ADLs) and Instrumental Activities of Daily Living (IADLs). Chi-square tests and multiple logistic regression analyses were performed using “R” statistical software. Results: Socioeconomic and demographic inequalities in Brazil can influence FC in seniors aged 80 years and older. Comparatively, urban long-lived people had a higher prevalence of difficulties for ADLs and rural ones showed more difficulties for IADLs. Among urban oldest seniors, female gender and lower-income were correlated with difficulties for IADLs. Among rural oldest seniors, female gender, stroke, joint disease, and inadequate weight independently were correlated with difficulties for ADLs, while the number of chronic diseases was associated with difficulties for IADLs. Conclusion: Financial constraints may favor the development of functional limitations among older seniors in large urban centers. In poor rural areas, inadequate nutritional status and chronic diseases may increase their susceptibility to functional decline.

scholarly journals Assessment of Daily Living of Patients with Spinal Cord Injury: A Cross-Sectional Study in Kermanshah

2021 ◽  
Vol 8 (3) ◽  
Author(s):  
Masoud Hatefi ◽  
AmirHosein Meisami ◽  
Alalleh Dalvand ◽  
Milad Borji
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Daily Living ◽  
Cross Sectional Study ◽  
Demographic Characteristics ◽  
Daily Activities ◽  
Sectional Study ◽  
Cross Sectional ◽  
Cord Injury ◽  
The Impact

Background: Spinal cord injuries (SCI) are a variety of chronic diseases that various causes such as trauma may contribute to its onset. One of the problems in these patients is the problem of physical activity and, consequently, daily activities. Objectives: This study aimed to assess daily living of patients with SCI. Methods: In this descriptive cross-sectional study in 2019, 120 patients with SCI in Kermanshah were included in the study using purposive sampling. The instruments used in this study fell into two parts. One part included the demographic characteristics of the SCI patients, and the other part was a questionnaire of the rate of the Impact on Participation and Autonomy questionnaire (IPA-P). Data were analyzed by SPSS software version 16 using descriptive tests such as mean and standard deviation. Results: The result showed there was a significant relationship between demographic characteristics such as education (P < 0.007), time of spinal cord injury (P < 0.01), and income (P = 0.000). Also, the results showed there was a relationship between Autonomy and Participation, and the age of patients and their autonomy and participation decreased with age (P = 0.000, R = 0.72). Most of the patients had severe problems with daily activities. Also, most patients had very poor scores in relation to daily living activities. Conclusions: Considering the low rate of participation and autonomy in patients with SCI, it is suggested to conduct studies aimed at improving their self-care and social participation.

scholarly journals Early Cerebral Hypoperfusion in Patients with Orthostatic Intolerance Without Tachycardia During Head-Up Tilt Test is Independent of Vasovagal Response

2021 ◽  
Author(s):  
J. Antonio González-Hermosillo ◽  
Alan Rubio-Vega ◽  
Karla A. F. González-Olvera ◽  
Manuel Sierra-Beltrán ◽  
Andrei Kostine ◽  
...  
Keyword(s):  
Orthostatic Intolerance ◽  
Cerebral Hypoperfusion ◽  
Tilt Test ◽  
Head Up Tilt ◽  
Head Up Tilt Test ◽  
Vasovagal Response

scholarly journals Relationship between activity of daily living and asteatosis in the lower legs among elderly residents in long-term care institutions: a cross-sectional study

2013 ◽  
Vol 12 (5) ◽  
pp. 586-589 ◽  
Author(s):  
Gojiro Nakagami ◽  
Nao Kimura ◽  
Kimie Takehara ◽  
Tetsuro Nakamura ◽  
Makoto Kawashima ◽  
...  
Keyword(s):  
Daily Living ◽  
Long Term Care ◽  
Cross Sectional Study ◽  
Activity Of Daily Living ◽  
Sectional Study ◽  
Cross Sectional ◽  
Term Care

Potential associated factors of functional disability in Chinese older inpatients: A multicenter cross-sectional study

2020 ◽  
Author(s):  
Hongpeng Liu ◽  
Jing Jiao ◽  
Chen Zhu ◽  
Minglei Zhu ◽  
Xianxiu Wen ◽  
...  
Keyword(s):  
Older Adults ◽  
Activities Of Daily Living ◽  
Daily Living ◽  
Functional Disability ◽  
Age Groups ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Older Inpatients ◽  
Hospital Wards

Abstract Background: Older adults are vulnerable to a decline in physical functioning, including basic activities of daily living (ADL) and higher-level instrumental activities of daily living (IADL). The causes of functional disability in older adults are multifactorial. A comprehensive understanding of these factors will contribute toward future health service planning. However, studies of ADL and IADL in Chinese older adults are insufficient. The aim of this study is to describe the level of ADL and IADL in different age groups and explore the factors associated with functional disability in Chinese older inpatients. Methods: We conducted a cross-sectional study consisted of 9,996 Chinese older inpatients aged 65 years and older. Participants were recruited from six provinces or municipality city in southwest (Sichuan province), northeast (Heilongjiang), south central (Hubei province), northern (Beijing municipality city), northwest (Qinghai province), and eastern China (Zhejiang province) from October 2018 to February 2019. The levels of ADL and IADL were measured by scores of the Barthel index and Instrumental Activities of Daily Living Scale in consecutive intervals from 65 years of age. After controlling for the cluster effect of hospital wards, a mixed-effect generalized linear model was used to examine the association between functional disability and covariates. Results: The average ADL score was 27.68±4.59 and the mean IADL score 6.76±2.01 for all participants. A negative correlation between scores and age was observed, and there was a significant difference in ADL and IADL scores among different age groups. The top negatively influential factor in ADL and IADL was stair climbing and shopping, respectively. After controlling for the cluster effect of hospital wards, aging, emaciation, frailty, depression, falling accidents in past 12 months, hearing dysfunction, cognitive dysfunction, urinary dysfunction, and defecation dysfunction were associated with ADL and IADL. Patients transitioned from the emergency department and other hospitals were also affected by ADL disability. Former smoking was associated with lower IADL scores. Higher level of education, living in a building without elevators, and current alcohol consumption were correlated with better IADL performance. Conclusion: Decreased functional ability was associated with the increasing age. Sociodemographic characteristics (such as age), physical health variables (frailty, emaciation, hearing dysfunction, urinary dysfunction, defecation dysfunction, falling accidents in past 12 months), and mental health variables (cognitive dysfunction, depression) were associated with functional disability. These findings potentially have major importance for the planning of hospital services, discharge planning, and post-discharge care.

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