scholarly journals Interaction between polygenic liability for schizophrenia and childhood adversity influences daily-life emotional dysregulation and psychosis proneness

2019 ◽  
Author(s):  
Lotta-Katrin Pries ◽  
Boris Klingenberg ◽  
Claudia Menne-Lothmann ◽  
Jeroen Decoster ◽  
Ruud van Winkel ◽  
...  
Keyword(s):  
Negative Affect ◽  
Positive Affect ◽  
Daily Life ◽  
Childhood Adversity ◽  
Mental States ◽  
Stress Sensitivity ◽  
Emotional Dysregulation ◽  
Life Stressors ◽  
Polygenic Risk Score ◽  
Psychosis Proneness

AbstractBackgroundThe earliest stages of the pluripotent psychopathology on the pathway to psychotic disorders is represented by emotional dysregulation and subtle psychosis expression, which can be measured using the Ecological Momentary Assessment (EMA). However, it is not clear to what degree common genetic and environmental risk factors for psychosis contribute to variation in these early expressions of psychopathology.MethodsIn this largest ever EMA study of a general population twin cohort including 593 adolescents and young adults between the ages of 15 and 35 years, we tested whether polygenic risk score for schizophrenia (PRS-S) interacts with childhood adversity (the Childhood Trauma Questionnaire score) and daily-life stressors to influence momentary mental state domains (negative affect, positive affect, and subtle psychosis expression) and stress-sensitivity measures.ResultsBoth childhood adversity and daily-life stressors were associated with increased negative affect, decreased positive affect, and increased subtle psychosis expression, while PRS-S was only associated with increased positive affect. No gene–environment correlation was detected. We have provided novel evidence for interaction effects between PRS-S and childhood adversity to influence momentary mental states [negative affect (b = 0.07, 95% CI 0.01 to 0.13, P = 0.013), positive affect (b = −0.05, 95% CI −0.10 to −0.00, P = 0.043), and subtle psychosis expression (b = 0.11, 95% CI 0.03 to 0.19, P = 0.007)] and stress-sensitivity measures.ConclusionExposure to childhood adversities, particularly in individuals with high PRS-S, is pleiotropically associated with emotional dysregulation and psychosis proneness.

scholarly journals 7.3 POLYGENIC RISK FOR SCHIZOPHRENIA MODERATES THE INFLUENCE OF CHILDHOOD ADVERSITY ON DAILY-LIFE EMOTIONAL DYSREGULATION AND PSYCHOSIS PRONENESS

2019 ◽  
Vol 45 (Supplement_2) ◽  
pp. S98-S98 ◽  
Author(s):  
Lotta-Katrin Pries ◽  
Boris Klingenberg ◽  
Claudia Menne-Lothmann ◽  
Jeroen Decoster ◽  
Ruud van Winkel ◽  
...  
Keyword(s):  
Daily Life ◽  
Childhood Adversity ◽  
Emotional Dysregulation ◽  
Polygenic Risk ◽  
Psychosis Proneness

scholarly journals Interaction Between Polygenic Liability for Schizophrenia and Childhood Adversity Influences Daily-Life Emotional Dysregulation and Psychosis Proneness

2020 ◽  
Vol 87 (9) ◽  
pp. S1-S2
Author(s):  
Lotta-Katrin Pries ◽  
Boris Klingenberg ◽  
Claudia Menne-Lothmann ◽  
Jeroen Decoster ◽  
Ruud van Winkel ◽  
...  
Keyword(s):  
Daily Life ◽  
Childhood Adversity ◽  
Emotional Dysregulation ◽  
Psychosis Proneness

Concurrent and Lagged Relations between Emotion Regulation and Affect in Adolescents’ Daily Life

2018 ◽  
Vol 21 ◽  
Author(s):  
Eliana Silva ◽  
Teresa Freire ◽  
Susana Faria
Keyword(s):  
Emotion Regulation ◽  
Negative Affect ◽  
Positive Affect ◽  
Sampling Method ◽  
Daily Life ◽  
Cognitive Reappraisal ◽  
Expressive Suppression ◽  
Daily Lives ◽  
Trait Level

AbstractA better understanding of emotion regulation (ER) within daily life is a growing focus of research. This study evaluated the average use of two ER strategies (cognitive reappraisal and expressive suppression) and concurrent and lagged relationships between these two ER strategies and affect (positive and negative affect) in the daily lives of adolescents. We also investigated the role of the same strategies at the trait level on these within-person relationships. Thirty-three adolescents provided 1,258 reports of their daily life by using the Experience Sampling Method for one week. Regarding the relative use of ER strategies, cognitive reappraisal (M = 2.87, SD = 1.58) was used more often than expressive suppression (M = 2.42, SD = 1.21). While the use of both strategies was positively correlated when evaluated in daily life (p = .01), the same did not occur at the trait level (p = .37). Multilevel analysis found that ER strategies were concurrently related to affect (p < .01), with the exception of cognitive reappraisal-positive affect relationship (p = .11). However, cognitive reappraisal predicted higher positive affect at the subsequent sampling moment ( β = 0.07, p = .03). The concurrent associations between cognitive reappraisal and negative affect vary as function of the use of this strategy at the trait level (β = 0.05, p = .02). Our findings highlighted the complex associations between daily ER strategies and affect of a normative sample of adolescents.

scholarly journals A Coordinated Analysis of Variance in Affect in Daily Life

Assessment ◽  
2018 ◽  
Vol 27 (8) ◽  
pp. 1683-1698 ◽  
Author(s):  
Stacey B. Scott ◽  
Martin J. Sliwinski ◽  
Matthew Zawadzki ◽  
Robert S. Stawski ◽  
Jinhyuk Kim ◽  
...  
Keyword(s):  
Negative Affect ◽  
Positive Affect ◽  
Ecological Momentary Assessment ◽  
Daily Life ◽  
Daily Diary ◽  
Levels Of Analysis ◽  
Total N ◽  
Ecological Momentary ◽  
Momentary Assessment ◽  
Widespread Interest

Despite widespread interest in variance in affect, basic questions remain pertaining to the relative proportions of between-person and within-person variance, the contribution of days and moments, and the reliability of these estimates. We addressed these questions by decomposing negative affect and positive affect variance across three levels (person, day, moment), and calculating reliability using a coordinated analysis of seven daily diary, ecological momentary assessment (EMA), and diary-EMA hybrid studies (across studies age = 18-84 years, total Npersons = 2,103, total Nobservations = 45,065). Across studies, within-person variance was sizeable (negative affect: 45% to 66%, positive affect: 25% to 74%); in EMA more within-person variance was attributable to momentary rather than daily level. Reliability was adequate to high at all levels of analysis (within-person: .73-.91; between-person: .96-1.00) despite different items and designs. We discuss the implications of these results for the design of future intensive studies of affect variance.

Genetic and Environmental Causes of Individual Differences in Daily Life Positive Affect and Reward Experience and Its Overlap with Stress-Sensitivity

2012 ◽  
Vol 42 (5) ◽  
pp. 778-786 ◽  
Author(s):  
Claudia Menne-Lothmann ◽  
Nele Jacobs ◽  
Catherine Derom ◽  
Evert Thiery ◽  
Jim van Os ◽  
...  
Keyword(s):  
Individual Differences ◽  
Positive Affect ◽  
Daily Life ◽  
Stress Sensitivity ◽  
Environmental Causes

A momentary assessment study of the reputed emotional phenotype associated with borderline personality disorder

2007 ◽  
Vol 38 (9) ◽  
pp. 1231-1239 ◽  
Author(s):  
J.-P. Glaser ◽  
J. Van Os ◽  
R. Mengelers ◽  
I. Myin-Germeys
Keyword(s):  
Borderline Personality Disorder ◽  
Personality Disorder ◽  
Negative Affect ◽  
Emotional Reactivity ◽  
Stress Reactivity ◽  
Daily Life ◽  
Stress Sensitivity ◽  
Borderline Personality ◽  
Healthy Controls ◽  
Borderline Patients

SUMMARYBackgroundStress is postulated to play an essential role in the expression of core borderline symptoms. However, the phenomenology of stress reactivity in borderline personality disorder remains unclear. The current study investigated the phenomenology of stress sensitivity in borderline personality disorder in the flow of daily life and compared this with stress sensitivity in patients suffering from psychotic disorders, a group so far known to report the largest reactivity to stress.MethodA total of 44 borderline patients, 42 patients with psychotic disorder and 49 healthy controls were studied with the Experience Sampling Method (a structured diary technique assessing current context and mood in daily life) to assess: (1) appraised subjective stress related to daily events and activities; and (2) emotional reactivity conceptualized as changes in positive and negative affect.ResultsMultilevel regression analysis revealed that subjects with borderline personality disorder experienced significantly more emotional reactivity to daily life stress compared with both patients with psychosis and healthy controls, as evidenced by a larger increase in negative affect and a larger decrease in positive affect following stress.ConclusionThese results are the first to ecologically validate the incorporation of stress reactive symptoms in the diagnosis of borderline personality disorder. Borderline patients continually react stronger than patients with psychosis and healthy controls to small disturbances that continually happen in the natural flow of everyday life. Altered emotional stress reactivity may define borderline personality disorder.

scholarly journals AGE DIFFERENCES IN CONCORDANCE BETWEEN LAB AND DAILY LIFE STRESS RESPONSES

2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S741-S741
Author(s):  
Gloria Luong ◽  
Carla M Arredondo
Keyword(s):  
Older Adults ◽  
Negative Affect ◽  
Positive Affect ◽  
Stress Responses ◽  
Life Stress ◽  
Stress Reactivity ◽  
Daily Life ◽  
Age Related ◽  
Affect Reactivity ◽  
Interpersonal Stressors

Abstract The literature is mixed with respect to how stress reactivity changes with age. Previous studies have overlooked contexts, ignoring whether stressors occurred in the laboratory or in daily life. The Health and Daily Experiences (HEADE) study includes 126 younger and older adults who completed both laboratory stressors and ecological momentary assessments (EMA) of affect and stressor experiences in daily life. We found that the laboratory stressor elicited the greatest levels of negative affect reactivity (i.e., larger increases in negative affect) and positive affect reactivity (i.e., larger reductions in positive affect) compared to the two types of daily life stressors. Interpersonal stressors were associated with greater negative and positive affect reactivity compared to non-interpersonal stressors in daily life. Younger adults exhibited greater stress reactivity than older adults. Together, these findings support age-related reductions in stress reactivity. Implications for understanding stressor-health links are discussed.

scholarly journals Interpersonal Interactions and Affect in Daily Life Among Midlife and Older Adults

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 773-773
Author(s):  
Robert Stawski ◽  
Dakota Witzel ◽  
Madeline Nichols ◽  
Susan Charles
Keyword(s):  
Negative Affect ◽  
Positive Affect ◽  
Age Differences ◽  
Daily Life ◽  
Well Being ◽  
National Study ◽  
Interpersonal Interactions ◽  
Emotional Wellbeing ◽  
Age Related ◽  
Diary Studies

Abstract Theories of age and emotional wellbeing posit that older age is associated with better affective well-being through avoidance or minimization of distressing experiences and prioritizing positive experiences and emotions. To test these theories, researchers have examined change in affect (i.e., reactivity) associated with negative interpersonal experiences in daily diary studies, given the compromising effects these interpersonal stressors exert on daily affect. In contrast, age differences in the potential affect-enhancing effects of positive interpersonal experiences have been comparatively neglected. Using the second wave of the National Study of Daily Experiences, we evaluated age differences in the frequency of daily negative and positive interpersonal interactions, as well as the affective responses to these interpersonal interactions. Positive and negative affect, as well as negative and positive interpersonal interactions were assessed on eight consecutive evenings. Analyses included 818 participants (Mage=53.3, SD=11.8, Range=34-83; 60% female) who experienced both negative and positive interpersonal interactions during the 8-day protocol. Preliminary results revealed increased frequency of negative interpersonal interactions and decreased frequency of positive interpersonal interactions with age (ps&lt;.01). Further, negative interpersonal interactions were associated with increases in negative affect and decreases in positive affect (ps&lt;.01), while positive interpersonal interactions were associated only with increased positive affect (p&lt;.01). Finally, modest evidence of age-related reductions in the affective impact of negative, but not positive, interpersonal interactions emerged (p=.03). Discussion will focus on how studies of interpersonal interactions in daily life can inform theories of aging and promote emotional wellbeing throughout adulthood and later life.

scholarly journals Affective Benefits of Nature Contact: The Role of Rumination

2021 ◽  
Vol 12 ◽  
Author(s):  
Gregory N. Bratman ◽  
Gerald Young ◽  
Ashish Mehta ◽  
Ihno Lee Babineaux ◽  
Gretchen C. Daily ◽  
...  
Keyword(s):  
Negative Affect ◽  
Positive Affect ◽  
Structural Equation ◽  
Daily Life ◽  
Equation Modeling ◽  
Positive And Negative Affect ◽  
Cross Sectional ◽  
Psychological Mechanisms ◽  
Nature Contact

Mounting evidence shows that nature contact is associated with affective benefits. However, the psychological mechanisms responsible for these effects are not well understood. In this study, we examined whether more time spent in nature was associated with higher levels of positive affect in general, and lower levels of negative affect and rumination in general. We also conducted a cross-sectional mediation analysis to examine whether rumination mediated the association of nature contact with affect. Participants (N = 617) reported their average time spent in nature each week, as well as their general levels of positive and negative affect, and the degree to which they typically engaged in rumination in daily life. We then used structural equation modeling to test our hypotheses. Our results support the hypothesis that nature contact is associated with general levels of affect, and that rumination mediates this association for negative affect, and marginally mediates this association for positive affect.

Evidence that genes for depression impact on the pathway from trauma to psychotic-like symptoms by occasioning emotional dysregulation

2011 ◽  
Vol 42 (2) ◽  
pp. 283-294 ◽  
Author(s):  
I. M. A. Kramer ◽  
C. J. P. Simons ◽  
I. Myin-Germeys ◽  
N. Jacobs ◽  
C. Derom ◽  
...  
Keyword(s):  
Childhood Trauma ◽  
Emotional Processing ◽  
Childhood Adversity ◽  
Stress Sensitivity ◽  
Emotional Dysregulation ◽  
Psychotic Symptoms ◽  
Psychotic Experiences ◽  
Multilevel Regression ◽  
Genetic Liability

BackgroundGenes for depression may act by making individuals more sensitive to childhood trauma. Given that childhood adversity is a risk factor for adult psychosis and symptoms of depression and psychosis tend to cluster within individuals and families, the aim was to examine whether the association between childhood adversity and psychotic-like symptoms is moderated by genetic liability for depression. A secondary aim was to determine to what degree a depression-related increase in stress sensitivity or depressive symptoms themselves occasioned the moderating effect.MethodFemale twins (n=508) completed both prospective and retrospective questionnaires regarding childhood adversity [the Symptom Checklist-90 – Revised (SCL-90-R) and SCID-I (psychotic symptoms)] and psychotic trait liability [the Community Assessment of Psychic Experiences (CAPE)]. Stress sensitivity was indexed by appraisals of event-related stress and negative affect (NA) in the flow of daily life, assessed with momentary assessment technology for five consecutive days. Multilevel regression analyses were used to examine moderation of childhood adversity by genetic liability for depression in the prediction of follow-up psychotic experiences.ResultsThe effect of childhood adversity was significantly moderated by genetic vulnerability for depression in the model of both follow-up psychotic experiences (SCL-90-R) and follow-up psychotic trait liability (CAPE). The moderation by genetic liability was mediated by depressive experience but not by stress sensitivity.ConclusionsGenetic liability for depression may potentiate the pathway from childhood adversity to psychotic-like symptoms through dysfunctional emotional processing of anomalous experiences associated with childhood trauma.

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