scholarly journals Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes

2005 ◽  
Vol 16 (1) ◽  
pp. 55-65 ◽  
Author(s):  
K. Kimura
Keyword(s):  
Large Scale ◽  
Alternative Promoters ◽  
Human Genes ◽  
Transcriptional Modulation ◽  
Identification And Characterization

scholarly journals Large-scale identification and characterization of human genes that activate NF-κB and MAPK signaling pathways

Oncogene ◽  
2003 ◽  
Vol 22 (21) ◽  
pp. 3307-3318 ◽  
Author(s):  
Akio Matsuda ◽  
Yutaka Suzuki ◽  
Goichi Honda ◽  
Shuji Muramatsu ◽  
Osamu Matsuzaki ◽  
...  
Keyword(s):  
Signaling Pathways ◽  
Large Scale ◽  
Mapk Signaling ◽  
Human Genes ◽  
Identification And Characterization ◽  
Mapk Signaling Pathways

scholarly journals Genome-Wide Identification and Characterization of Long Non-Coding RNAs in Peanut

Genes ◽  
2019 ◽  
Vol 10 (7) ◽  
pp. 536 ◽  
Author(s):  
Xiaobo Zhao ◽  
Liming Gan ◽  
Caixia Yan ◽  
Chunjuan Li ◽  
Quanxi Sun ◽  
...  
Keyword(s):  
Large Scale ◽  
Target Genes ◽  
Sequencing Data ◽  
Regulatory Processes ◽  
Genome Wide ◽  
Non Coding Rnas ◽  
Identification And Characterization ◽  
Lower Expression ◽  
Weighted Correlation

Long non-coding RNAs (lncRNAs) are involved in various regulatory processes although they do not encode protein. Presently, there is little information regarding the identification of lncRNAs in peanut (Arachis hypogaea Linn.). In this study, 50,873 lncRNAs of peanut were identified from large-scale published RNA sequencing data that belonged to 124 samples involving 15 different tissues. The average lengths of lncRNA and mRNA were 4335 bp and 954 bp, respectively. Compared to the mRNAs, the lncRNAs were shorter, with fewer exons and lower expression levels. The 4713 co-expression lncRNAs (expressed in all samples) were used to construct co-expression networks by using the weighted correlation network analysis (WGCNA). LncRNAs correlating with the growth and development of different peanut tissues were obtained, and target genes for 386 hub lncRNAs of all lncRNAs co-expressions were predicted. Taken together, these findings can provide a comprehensive identification of lncRNAs in peanut.

Large-scale identification and characterization of phenolic compounds and their marker–trait association in wheat

Euphytica ◽  
2020 ◽  
Vol 216 (8) ◽  
Author(s):  
Monica Sharma ◽  
Mohammed Saba Rahim ◽  
Pankaj Kumar ◽  
Ankita Mishra ◽  
Himanshu Sharma ◽  
...  
Keyword(s):  
Phenolic Compounds ◽  
Large Scale ◽  
Trait Association ◽  
Identification And Characterization

scholarly journals Identification and Characterization of Alternative Promoters, Transcripts and Protein Isoforms of Zebrafish R2 Gene

PLoS ONE ◽  
2011 ◽  
Vol 6 (8) ◽  
pp. e24089 ◽  
Author(s):  
Hanqiao Shang ◽  
Qing Li ◽  
Guohui Feng ◽  
Zongbin Cui
Keyword(s):  
Protein Isoforms ◽  
Alternative Promoters ◽  
Identification And Characterization

scholarly journals Large-scale identification and characterization of alternative splicing variants of human gene transcripts using 56 419 completely sequenced and manually annotated full-length cDNAs

2006 ◽  
Vol 34 (14) ◽  
pp. 3917-3928 ◽  
Author(s):  
Jun-ichi Takeda ◽  
Yutaka Suzuki ◽  
Mitsuteru Nakao ◽  
Roberto A. Barrero ◽  
Kanako O. Koyanagi ◽  
...  
Keyword(s):  
Alternative Splicing ◽  
Large Scale ◽  
Human Gene ◽  
Full Length ◽  
Splicing Variants ◽  
Gene Transcripts ◽  
Identification And Characterization

scholarly journals Identification and characterization of growing large-scale en-echelon fractures in a salt mine

2013 ◽  
Vol 196 (2) ◽  
pp. 1092-1105 ◽  
Author(s):  
Samira Maghsoudi ◽  
Sebastian Hainzl ◽  
Simone Cesca ◽  
Torsten Dahm ◽  
Diethelm Kaiser
Keyword(s):  
Large Scale ◽  
Salt Mine ◽  
Identification And Characterization

scholarly journals Transferrin-a modulates hepcidin expression in zebrafish embryos

Blood ◽  
2009 ◽  
Vol 113 (12) ◽  
pp. 2843-2850 ◽  
Author(s):  
Paula G. Fraenkel ◽  
Yann Gibert ◽  
Jason L. Holzheimer ◽  
Victoria J. Lattanzi ◽  
Sarah F. Burnett ◽  
...  
Keyword(s):  
Large Scale ◽  
Critical Role ◽  
Hypochromic Anemia ◽  
Zebrafish Embryos ◽  
Genetic Screens ◽  
Hepcidin Expression ◽  
Morpholino Knockdown ◽  
Low Levels ◽  
Identification And Characterization

Abstract The iron regulatory hormone hepcidin is transcriptionally up-regulated in response to iron loading, but the mechanisms by which iron levels are sensed are not well understood. Large-scale genetic screens in the zebrafish have resulted in the identification of hypochromic anemia mutants with a range of mutations affecting conserved pathways in iron metabolism and heme synthesis. We hypothesized that transferrin plays a critical role both in iron transport and in regulating hepcidin expression in zebrafish embryos. Here we report the identification and characterization of the zebrafish hypochromic anemia mutant, gavi, which exhibits transferrin deficiency due to mutations in transferrin-a. Morpholino knockdown of transferrin-a in wild-type embryos reproduced the anemia phenotype and decreased somite and terminal gut iron staining, while coinjection of transferrin-a cRNA partially restored these defects. Embryos with transferrin-a or transferrin receptor 2 (TfR2) deficiency exhibited low levels of hepcidin expression, however anemia, in the absence of a defect in the transferrin pathway, failed to impair hepcidin expression. These data indicate that transferrin-a transports iron and that hepcidin expression is regulated by a transferrin-a–dependent pathway in the zebrafish embryo.

scholarly journals Identification and Characterization of Human Genes Targeted by Natural Selection

2008 ◽  
Vol 6 (4) ◽  
pp. 173-180
Author(s):  
Ha-Jung Ryu ◽  
Young-Joo Kim ◽  
Young-Kyu Park ◽  
Jae-Jung Kim ◽  
Mi-Young Park ◽  
...  
Keyword(s):  
Natural Selection ◽  
Human Genes ◽  
Identification And Characterization
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