Proposal for the formation of ultracold deeply bound RbSr dipolar molecules by all-optical methods

AbstractIn the past 10 years, the use of light has become irreplaceable for the optogenetic study and control of neurons and neural circuits. Optical techniques are however limited by scattering and can only see through a depth of few hundreds µm in living tissues. GRIN lens based micro-endoscopes represent a powerful solution to reach deeper regions. In this work we demonstrate that cutting edge optical methods for the precise photostimulation of multiple neurons in three dimensions can be performed through a GRIN lens. By spatio-temporally shaping a laser beam in the two-photon regime we project several tens of targets, spatially confined to the size of a single cell, in a volume of 150×150×400 μm3. We then apply such concept to the optogenetic stimulation of multiple neurons simultaneously in vivo in mice. Our work paves the way for an all-optical investigation of neural circuits at previously unattainable depths.

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Optogenetic strategies for high-efficiency all-optical interrogation using blue light-sensitive opsins

eLife ◽

10.7554/elife.63359 ◽

2021 ◽

Vol 10 ◽

Author(s):

Angelo Forli ◽

Matteo Pisoni ◽

Yoav Printz ◽

Ofer Yizhar ◽

Tommaso Fellin

Keyword(s):

Blue Light ◽

Large Scale ◽

High Efficiency ◽

Average Power ◽

Optical Methods ◽

Neuronal Ensembles ◽

Two Photon ◽

All Optical ◽

Stimulation Of

All-optical methods for imaging and manipulating brain networks with high spatial resolution are fundamental to study how neuronal ensembles drive behavior. Stimulation of neuronal ensembles using holographic techniques requires high-sensitivity actuators to avoid photodamage and heating. Moreover, two-photon-excitable opsins should be insensitive to light at wavelengths used for imaging. To achieve this goal, we developed a novel soma-targeted variant of the large-conductance blue light-sensitive opsin CoChR (stCoChR). In the mouse cortex in vivo, we combined holographic two-photon stimulation of stCoChR with an amplified laser tuned at the opsin absorption peak and imaging of the red-shifted indicator jRCaMP1a. Compared to previously characterized blue light-sensitive soma-targeted opsins in vivo, stCoChR allowed neuronal stimulation with more than 10-fold lower average power and no spectral crosstalk. The combination of stCoChR, tuned amplified laser stimulation, and red-shifted functional indicators promises to be a powerful tool for large-scale interrogation of neural networks in the intact brain.

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Gilbert damping and critical real-space trajectory of L10-ordered FePt films investigated by magnetic-field-induction and all-optical methods

Applied Physics Express ◽

10.7567/apex.7.113004 ◽

2014 ◽

Vol 7 (11) ◽

pp. 113004 ◽

Cited By ~ 5

Author(s):

Kyeong-Dong Lee ◽

Hyon-Seok Song ◽

Ji-Wan Kim ◽

Hyun Seok Ko ◽

Jeong-Woo Sohn ◽

...

Keyword(s):

Magnetic Field ◽

Real Space ◽

Magnetic Field Induction ◽

Optical Methods ◽

Gilbert Damping ◽

Field Induction ◽

All Optical

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Optical Ultrasound Generation and Detection for Intravascular Imaging: A Review

Journal of Healthcare Engineering ◽

10.1155/2018/3182483 ◽

2018 ◽

Vol 2018 ◽

pp. 1-14 ◽

Cited By ~ 3

Author(s):

Tianrui Zhao ◽

Lei Su ◽

Wenfeng Xia

Keyword(s):

Ultrasound Imaging ◽

Photoacoustic Imaging ◽

Spatial Location ◽

Imaging Systems ◽

Optical Methods ◽

Great Promise ◽

Atheromatous Plaque ◽

Imaging Method ◽

Intravascular Imaging ◽

All Optical

Combined ultrasound and photoacoustic imaging has attracted significant interests for intravascular imaging such as atheromatous plaque detection, with ultrasound imaging providing spatial location and morphology and photoacoustic imaging highlighting molecular composition of the plaque. Conventional ultrasound imaging systems utilize piezoelectric ultrasound transducers, which suffer from limited frequency bandwidths and reduced sensitivity with miniature transducer elements. Recent advances on optical methods for both ultrasound generation and detection have shown great promise, as they provide efficient and ultrabroadband ultrasound generation and sensitive and ultrabroadband ultrasound detection. As such, all-optical ultrasound imaging has a great potential to become a next generation ultrasound imaging method. In this paper, we review recent developments on optical ultrasound transmitters, detectors, and all-optical ultrasound imaging systems, with a particular focus on fiber-based probes for intravascular imaging. We further discuss our thoughts on future directions on developing combined all-optical photoacoustic and ultrasound imaging systems for intravascular imaging.

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All-optical scheme for strongly enhanced production of a Bose-Einstein condensate of dipolar molecules in the vibronic ground state

Physical Review A ◽

10.1103/physreva.81.043627 ◽

2010 ◽

Vol 81 (4) ◽

Cited By ~ 1

Author(s):

Matt Mackie ◽

Catherine Debrosse

Keyword(s):

Ground State ◽

Einstein Condensate ◽

Optical Scheme ◽

Bose Einstein Condensate ◽

Enhanced Production ◽

Dipolar Molecules ◽

All Optical ◽

Bose Einstein

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All-Optical Fiber Interferometer-Based Methods for Ultra-Wideband Signal Generation

Journal of Electrical and Computer Engineering ◽

10.1155/2012/314872 ◽

2012 ◽

Vol 2012 ◽

pp. 1-6

Author(s):

Kais Dridi ◽

Habib Hamam

Keyword(s):

Optical Fibers ◽

Input Pulse ◽

Federal Communication Commission ◽

Cost Effective ◽

Impulse Radio ◽

Pulse Generation ◽

Ultra Wideband ◽

Optical Methods ◽

All Optical ◽

Radio Signals

We report two new, simple, and cost-effective all-optical methods to generate ultra-wideband (UWB) impulse radio signals. The proposed methods are based on fiber-interferometric structures, where an input pulse is split and propagates along the two interferometer arms. The interference of these pulses at the output of the interferometer leads to UWB pulse generation. A theoretical analysis is provided and some relevant simulation results are presented. Large bandwidths are obtained while satisfying the requirements of the Federal Communication Commission (FCC). With these two techniques, UWB pulses can be readily generated and cost-effectively propagated through optical fibers.

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Synthesis and dissociation of soliton molecules in parallel optical-soliton reactors

Light Science & Applications ◽

10.1038/s41377-021-00558-x ◽

2021 ◽

Vol 10 (1) ◽

Author(s):

Wenbin He ◽

Meng Pang ◽

Dung-Han Yeh ◽

Jiapeng Huang ◽

Philip. St. J. Russell

Keyword(s):

Optical Control ◽

Optical Methods ◽

Fibre Laser ◽

Crucial Importance ◽

Experimental Conditions ◽

Soliton Interactions ◽

Large Numbers ◽

All Optical ◽

Potential Applications ◽

Mode Locked Lasers

AbstractMode-locked lasers have been widely used to explore interactions between optical solitons, including bound-soliton states that may be regarded as “photonic molecules”. Conventional mode-locked lasers normally, however, host at most only a few solitons, which means that stochastic behaviours involving large numbers of solitons cannot easily be studied under controlled experimental conditions. Here we report the use of an optoacoustically mode-locked fibre laser to create hundreds of temporal traps or “reactors” in parallel, within each of which multiple solitons can be isolated and controlled both globally and individually using all-optical methods. We achieve on-demand synthesis and dissociation of soliton molecules within these reactors, in this way unfolding a novel panorama of diverse dynamics in which the statistics of multi-soliton interactions can be studied. The results are of crucial importance in understanding dynamical soliton interactions and may motivate potential applications for all-optical control of ultrafast light fields in optical resonators.

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Correlation analysis of radiation damage

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100108210 ◽

1978 ◽

Vol 36 (1) ◽

pp. 214-215

Author(s):

R. Hegerl ◽

A. Feltynowski ◽

B. Grill

Keyword(s):

Electron Microscopy ◽

Independent Random Variables ◽

Optical Parameters ◽

Bright Field Image ◽

Bright Field ◽

Expectation Value ◽

All Optical ◽

Image Element ◽

Stochastic Series ◽

The Common

Till now correlation functions have been used in electron microscopy for two purposes: a) to find the common origin of two micrographs representing the same object, b) to check the optical parameters e. g. the focus. There is a third possibility of application, if all optical parameters are constant during a series of exposures. In this case all differences between the micrographs can only be caused by different noise distributions and by modifications of the object induced by radiation.Because of the electron noise, a discrete bright field image can be considered as a stochastic series Pm,where i denotes the number of the image and m (m = 1,.., M) the image element. Assuming a stable object, the expectation value of Pm would be Ηm for all images. The electron noise can be introduced by addition of stationary, mutual independent random variables nm with zero expectation and the variance. It is possible to treat the modifications of the object as a noise, too.

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