Electric field induced in cells in the human body when this is exposed to low-frequency electric fields

1998 ◽  
Vol 58 (2) ◽  
pp. 2363-2369 ◽  
Author(s):  
Ronold W. P. King ◽  
Tai Tsun Wu
Keyword(s):  
Electric Field ◽  
Electric Fields ◽  
Human Body ◽  
Low Frequency ◽  
In Cells

Pulsed DC electric fields couple to natural NAD(P)H oscillations in HT-1080 fibrosarcoma cells

2001 ◽  
Vol 114 (8) ◽  
pp. 1515-1520 ◽  
Author(s):  
A.J. Rosenspire ◽  
A.L. Kindzelskii ◽  
H.R. Petty
Keyword(s):  
Electric Field ◽  
Electric Fields ◽  
Cell Function ◽  
Low Frequency ◽  
Reactive Oxygen Metabolites ◽  
Pulsed Dc ◽  
Fibrosarcoma Cells ◽  
Chemotactic Factors ◽  
Oxygen Metabolites ◽  
Dc Electric Fields

Previously, we have demonstrated that NAD(P)H levels in neutrophils and macrophages are oscillatory. We have also found that weak ultra low frequency AC or pulsed DC electric fields can resonate with, and increase the amplitude of, NAD(P)H oscillations in these cells. For these cells, increased NAD(P)H amplitudes directly signal changes in behavior in the absence of cytokines or chemotactic factors. Here, we have studied the effect of pulsed DC electric fields on HT-1080 fibrosarcoma cells. As in neutrophils and macrophages, NAD(P)H levels oscillate. We find that weak (~10(-)(5) V/m), but properly phased DC (pulsed) electric fields, resonate with NAD(P)H oscillations in polarized and migratory, but not spherical, HT-1080 cells. In this instance, electric field resonance signals an increase in HT-1080 pericellular proteolytic activity. Electric field resonance also triggers an immediate increase in the production of reactive oxygen metabolites. Under resonance conditions, we find evidence of DNA damage in HT-1080 cells in as little as 5 minutes. Thus the ability of external electric fields to effect cell function and physiology by acting on NAD(P)H oscillations is not restricted to cells of the hematopoietic lineage, but may be a universal property of many, if not all polarized and migratory eukaryotic cells.

scholarly journals Computation of currents induced by ELF electric fields in anisotropic human tissues using the Finite Integration Technique (FIT)

2005 ◽  
Vol 3 ◽  
pp. 227-231 ◽  
Author(s):  
V. C. Motrescu ◽  
U. van Rienen
Keyword(s):  
Dielectric Properties ◽  
Electromagnetic Fields ◽  
Electric Fields ◽  
Human Body ◽  
Low Frequency ◽  
Integration Technique ◽  
Human Body Model ◽  
Body Model ◽  
Finite Integration Technique ◽  
Muscle Tissues

Abstract. In the recent years, the task of estimating the currents induced within the human body by environmental electromagnetic fields has received increased attention from scientists around the world. While important progress was made in this direction, the unpredictable behaviour of living biological tissue made it difficult to quantify its reaction to electromagnetic fields and has kept the problem open. A successful alternative to the very difficult one of performing measurements is that of computing the fields within a human body model using numerical methods implemented in a software code. One of the difficulties is represented by the fact that some tissue types exhibit an anisotropic character with respect to their dielectric properties. Our work consists of computing currents induced by extremely low frequency (ELF) electric fields in anisotropic muscle tissues using in this respect, a human body model extended with muscle fibre orientations as well as an extended version of the Finite Integration Technique (FIT) able to compute fully anisotropic dielectric properties.

scholarly journals BEM Modelling of High Voltage ELF electric field applied to a 3D pregnant woman model

2010 ◽  
Vol 6 (1) ◽  
pp. 31 ◽  
Author(s):  
Cristina Peratta ◽  
Andres Peratta ◽  
Dragan Poljak
Keyword(s):  
Pregnant Woman ◽  
Electric Field ◽  
Electric Fields ◽  
High Voltage ◽  
Medical Information ◽  
Three Dimensional ◽  
Low Frequency ◽  
Element Model ◽  
The Body ◽  
Geometrical Properties

The paper introduces a three dimensional multidomainboundary element model of a pregnant woman and foetus for the analysis of exposure to high voltage extremely low frequency electric fields. The definition of the differentphysical and geometrical properties of the relevant tissues is established according to medical information available in existing literature. The model takes into account changes in geometry, body mass, body fat, and overall chemical composition in the body which influence the electrical properties, throughout the different gestational periods. The developed model is used to solve the case of exposure to overhead power transmission lines at different stages of pregnancy including weeks 8, 13, 26 and 38. The results obtained are in line with those published in the earlier works considering different approaches. In addition, a sensitivity analysis involving varying scenarios of conductivity, foetus postures and geometry for each stage is defined and solved. Finally, a correlation between the externally applied electric field and the current density inside the foetus is established and the zones of maximum exposure are identified.

Sensitivity to change in electrical environment: a new bioelectric effect

1980 ◽  
Vol 239 (5) ◽  
pp. R424-R427 ◽  
Author(s):  
A. A. Marino ◽  
J. M. Cullen ◽  
M. Reichmanis ◽  
R. O. Becker ◽  
F. X. Hart
Keyword(s):  
Electric Field ◽  
Blood Cell ◽  
Electric Fields ◽  
Red Blood Cell ◽  
Low Frequency ◽  
Sensitivity To Change ◽  
Bioelectric Effect ◽  
Cell Concentrations ◽  
Inappropriate Choice

The action of a 60-Hz, 5 kV/m electric field on erythrocyte parameters in mice was determined. No effects attributable to the magnitude of the field were found, but a transition either from or to an environment containing the field caused decreased red blood cell concentrations and decreased hematocrits. The failure of others to observe effects on erythrocyte parameters following exposure to low-frequency electric fields may have been due to an inappropriate choice of duration of exposure.

The Experimental Study on the Influence of Human Body to Measurement of High Voltage Power Frequency Electric Field

2013 ◽  
Vol 303-306 ◽  
pp. 482-488
Author(s):  
Kai Mao ◽  
Jin Gang Wang ◽  
Xu Dong Deng ◽  
Wei He ◽  
Zuo Peng Zhang
Keyword(s):  
Electromagnetic Field ◽  
Electric Field ◽  
Electric Fields ◽  
High Voltage ◽  
Human Body ◽  
Enhancement Factor ◽  
Electric Field Distribution ◽  
Field Distortion ◽  
Power Frequency ◽  
Frequency Electric Field

Based on the basic theory of electromagnetic field, the Electric Field Distortion (EFD) in power frequency electric field caused by induced current of human body has been analyzed. The enhancement factor of the electric field distortion is introduced to reduce the influences caused by human body in the measurement of high voltage electric fields. The Ansoft Maxwell is used to simulate and calculate the electric field distribution under the influence of the human body to have the value of enhancement factor. In addition, the enhancement factor has been corrected by experiment with the electromagnetic field analyzer EFA300. With the enhancement factor introduced in this paper, the measurement error can be reduced.

Characterization of interactive force acting on colloidal particles near an electrode in presence of a high-frequency (>10 kHz) AC electric field using particle diffusometry

2021 ◽  
Vol 1 (1) ◽  
Author(s):  
Kshitiz Gupta ◽  
Dong Hoon Lee ◽  
Steven T. Wereley ◽  
Stuart J. Williams
Keyword(s):  
Electric Field ◽  
Electric Fields ◽  
Particle Motion ◽  
Electrode Surface ◽  
High Frequency ◽  
Colloidal Particles ◽  
Low Frequency ◽  
Double Layers ◽  
Average Height ◽  
Ac Electric Field

Colloidal particles like polystyrene beads and metallic micro and nanoparticles are known to assemble in crystal-like structures near an electrode surface under both DC and AC electric fields. Various studies have shown that this self-assembly is governed by a balance between an attractive electrohydrodynamic (EHD) force and an induced dipole-dipole repulsion (Trau et al., 1997). The EHD force originates from electrolyte flow caused by interaction between the electric field and the polarized double layers of both the particles and the electrode surface. The particles are found to either aggregate or repel from each other on application of electric field depending on the mobility of the ions in the electrolyte (Woehl et al., 2014). The particle motion in the electrode plane is studied well under various conditions however, not as many references are available in the literature that discuss the effects of the AC electric field on their out-of-plane motion, especially at high frequencies (>10 kHz). Haughey and Earnshaw (1998), and Fagan et al. (2005) have studied the particle motion perpendicular to the electrode plane and their average height from the electrode mostly in presence of DC or low frequency AC (<1 kHz) electric field. However, these studies do not provide enough insight towards the effects of high frequency (>10 kHz) electric field on the particles’ motion perpendicular to the electrode plane.  

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