ON 30 March 1908, there was a sale of drawings and pictures in London, at Christie’s, and many of them came from the home of Mrs Caleb Rose of Ipswich—she died in May 1907 at the age of 89. Mrs Rose, the widow of Dr Caleb Rose, had been previously the wife of James Norton Sherrington of The Hall, Caister, near Norwich, and she was the greatly beloved mother of Charles Scott Sherrington. Looking back over exactly half a century I can place the Christie sale as the turning point of my father’s life; it meant for him that the home he had loved so much was gone for ever and, from that time onwards, the outlook was concentrated on the future not on the past, except for those unutterably happy memories which remained vivid to him until the very end, for he spoke to me of them with some yearning the evening before his death.