Spare Parts Procurement Planning at KM Trans Logistics

2014 ◽  
pp. 1-17
Author(s):  
Debjit Roy ◽  
Arindam Bandyopadhyay
Keyword(s):  
Inventory Management ◽  
Critical Role ◽  
Spare Parts ◽  
Storage Space ◽  
Spare Parts Inventory ◽  
Business Profitability ◽  
Selection Of ◽  
Procurement Planning

Inventory management plays a critical role in managing business profitability. Through this case, the participants will understand the role of managing inventory for timely workshop operations. Further, too much inventory can erode business margins and occupy storage space. This case also highlights the selection of an appropriate inventory review policy for managing the spare parts inventory.

scholarly journals Investigating the role of noncoding regulatory DNA in plasmid development for Yarrowia lipolytica

2020 ◽  
Author(s):  
Carmen Lopez ◽  
Mingfeng Cao ◽  
Zhanyi Yao ◽  
Zengyi Shao
Keyword(s):  
Yarrowia Lipolytica ◽  
Plasmid Stability ◽  
Critical Role ◽  
Fold Increase ◽  
Microbial Cell Factories ◽  
Cell Factories ◽  
Expression Platform ◽  
Regulatory Dna ◽  
Selection Of

Production of industrially relevant compounds in microbial cell factories can employ either genomes or plasmids as an expression platform. Selection of plasmids as pathway carriers is advantageous for rapid demonstration but poses a challenge of stability. Yarrowia lipolytica has attracted great attention in the past decade for the biosynthesis of chemicals related to fatty acids at titers attractive to industry, and many genetic tools have been developed to explore its oleaginous potential. Our recent studies on the autonomously replicating sequences (ARSs) of nonconventional yeasts revealed that the ARSs from Y. lipolytica showcase a unique structure that includes a previously unannotated sequence (spacer) linking the origin of replication (ORI) and the centromeric (CEN) element and plays a critical role in modulating plasmid behavior. Maintaining a native 645-bp spacer yielded a 4.5-fold increase in gene expression and higher plasmid stability compared to a more universally employed minimized ARS. Testing the modularity of the ARS sub-elements indicated that plasmid stability exhibits a pronounced cargo dependency. Instability caused both plasmid loss and intramolecular rearrangements. Altogether, our work clarifies the appropriate application of various ARSs for the scientific community and sheds light on a previously unexplored DNA element as a potential target for engineering Y. lipolytica.

scholarly journals The critical role of BAP1 mutation in the prognosis and treatment selection of kidney renal clear cell carcinoma

2020 ◽  
Vol 9 (4) ◽  
pp. 1725-1734
Author(s):  
Guobin Tan ◽  
Zijun Xuan ◽  
Zhiqin Li ◽  
Shuitong Huang ◽  
Guangming Chen ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Clear Cell ◽  
Clear Cell Carcinoma ◽  
Critical Role ◽  
Renal Clear Cell Carcinoma ◽  
Treatment Selection ◽  
Selection Of

scholarly journals Understanding the role of antibody glycosylation through the lens of severe viral and bacterial diseases

Glycobiology ◽  
2020 ◽  
Vol 30 (4) ◽  
pp. 241-253 ◽  
Author(s):  
Edward B Irvine ◽  
Galit Alter
Keyword(s):  
Infectious Diseases ◽  
Critical Role ◽  
Functional Roles ◽  
Bacterial Diseases ◽  
Humoral Immune ◽  
Class Switch ◽  
Antibody Isotypes ◽  
Specific Control ◽  
Selection Of

Abstract Abundant evidence points to a critical role for antibodies in protection and pathology across infectious diseases. While the antibody variable domain facilitates antibody binding and the blockade of infection, the constant domain (Fc) mediates cross talk with the innate immune system. The biological activity of the Fc region is controlled genetically via class switch recombination, resulting in the selection of distinct antibody isotypes and subclasses. However, a second modification is made to all antibodies, via post-translational changes in antibody glycosylation. Studies from autoimmunity and oncology have established the role of immunoglobulin G (IgG) Fc glycosylation as a key regulator of humoral immune activity. However, a growing body of literature, exploring IgG Fc glycosylation through the lens of infectious diseases, points to the role of inflammation in shaping Fc-glycan profiles, the remarkable immune plasticity in antibody glycosylation across pathogen-exposed populations, the canonical and noncanonical functions of glycans and the existence of antigen-specific control over antibody Fc glycosylation. Ultimately, this work provides critical new insights into the functional roles for antibody glycosylation as well as lays the foundation for leveraging antibody glycosylation to drive prevention or control across diseases.

scholarly journals The Role of ERP Information to Support Decision Making Process: Field Study on Panda Retail Company (Mobile Inventory Management System)

2020 ◽  
Vol 14 (16) ◽  
pp. 133
Author(s):  
Ahmed M. Alghazali ◽  
Uthman M. Ageeli
Keyword(s):  
Decision Making ◽  
Inventory Management ◽  
Management System ◽  
Critical Role ◽  
Theoretical Data ◽  
Decision Making Process ◽  
Inventory Management System ◽  
Retail Company ◽  
Support Decision Making

The ERP is the main source of business data while store mobile inventory management is one of very important modules in ERP that cover a critical role for retail organizations such as Panda retail company. The goal of this study is to show the high correlation between information and effective decision-making process. Descriptive analysis research method was used in this study where theoretical data collected from published papers, in Jeddah city (60) employees of mobile inventory management system users participated the survey and statistical techniques such as frequency tables, Percentages, Average value, standard deviation, etc. This used survey consists of 3 companies namely the effectiveness of information to support decision making, the effectiveness of store mobile inventory management at Panda retail company, the effectiveness of ERP for organizations. The key results of this study clarifies that it’s very important to have as much as possible data and the relationships between data at any point of time to identify problems, analyze them in order to make the most effective decisions and role of ERP in providing such information at any point of time. Recommendations had been provided such as the importunacy of ERP, modern business applications, and technology to improve business outcomes and provide continues learning and development culture for employees to increase their competencies to use these digital tools.

Metaphors we manage and develop quality by

2020 ◽  
Vol 12 (4) ◽  
pp. 405-416
Author(s):  
Johan Lilja ◽  
Pernilla Ingelsson ◽  
Kristen Snyder ◽  
Ingela Bäckström ◽  
Christer Hedlund
Keyword(s):  
Quality Management ◽  
Literature Review ◽  
Design Methodology ◽  
Dynamic Properties ◽  
Critical Role ◽  
Critical Discussion ◽  
Future Research ◽  
Content Type ◽  
Selection Of

Purpose Metaphors are a powerful and human way of understanding and experiencing one kind of thing in terms of another. In quality management (QM), several metaphors are used to describe and bring to life the often-abstract QM concepts and systems. These metaphors are of great importance for how QM is understood, communicated and practiced. However, the metaphors of QM have seldom been systematically screened or put in focus, neither the topic of a critical discussion. The purpose of this paper is hence to contribute with a screening of the metaphors currently used, within QM literature and in practice among QM leaders, and then elaborate on their potential for improvement and development. Design/methodology/approach The paper is based on a literature review combined with interviews of QM leaders. Findings The paper highlights that the current QM metaphors provide intuitive associations to properties such as stability, shelter, and structure, but not to the important dynamic properties of QM, such as learning, or to the critical role of people in QM. What can be seen as core properties of QM are communicated by texts or labels added on to metaphors with properties that often are in sharp contrast to them. The paper also provides suggestions for further improvements and development. Originality/value The paper highlights the area of metaphors within QM as an important area for future research. It also provides insights concerning the successful use and selection of metaphors in future QM practice.

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