scholarly journals MapReduce Model using FPGA Acceleration for Chromosome Y Sequence Mapping

IEEE Access ◽  
2021 ◽  
pp. 1-1
Author(s):  
Asmaa G. Seliem ◽  
Hesham F. A. Hamed ◽  
Wael Abouelwafa
Author(s):  
Edward B. Fernandez ◽  
Walid A. Najjar ◽  
Stefano Lonardi ◽  
Jason Villarreal

Author(s):  
Mykhajlo Klymash ◽  
Olena Hordiichuk — Bublivska ◽  
Ihor Tchaikovskyi ◽  
Oksana Urikova

In this article investigated the features of processing large arrays of information for distributed systems. A method of singular data decomposition is used to reduce the amount of data processed, eliminating redundancy. Dependencies of com­putational efficiency on distributed systems were obtained using the MPI messa­ging protocol and MapReduce node interaction software model. Were analyzed the effici­ency of the application of each technology for the processing of different sizes of data: Non — distributed systems are inefficient for large volumes of information due to low computing performance. It is proposed to use distributed systems that use the method of singular data decomposition, which will reduce the amount of information processed. The study of systems using the MPI protocol and MapReduce model obtained the dependence of the duration calculations time on the number of processes, which testify to the expediency of using distributed computing when processing large data sets. It is also found that distributed systems using MapReduce model work much more efficiently than MPI, especially with large amounts of data. MPI makes it possible to perform calculations more efficiently for small amounts of information. When increased the data sets, advisable to use the Map Reduce model.


Author(s):  
M. Ilayaraja ◽  
S. Hemalatha ◽  
P. Manickam ◽  
K. Sathesh Kumar ◽  
K. Shankar

Cloud computing is characterized as the arrangement of assets or administrations accessible through the web to the clients on their request by cloud providers. It communicates everything as administrations over the web in view of the client request, for example operating system, organize equipment, storage, assets, and software. Nowadays, Intrusion Detection System (IDS) plays a powerful system, which deals with the influence of experts to get actions when the system is hacked under some intrusions. Most intrusion detection frameworks are created in light of machine learning strategies. Since the datasets, this utilized as a part of intrusion detection is Knowledge Discovery in Database (KDD). In this paper detect or classify the intruded data utilizing Machine Learning (ML) with the MapReduce model. The primary face considers Hadoop MapReduce model to reduce the extent of database ideal weight decided for reducer model and second stage utilizing Decision Tree (DT) classifier to detect the data. This DT classifier comprises utilizing an appropriate classifier to decide the class labels for the non-homogeneous leaf nodes. The decision tree fragment gives a coarse section profile while the leaf level classifier can give data about the qualities that influence the label inside a portion. From the proposed result accuracy for detection is 96.21% contrasted with existing classifiers, for example, Neural Network (NN), Naive Bayes (NB) and K Nearest Neighbor (KNN).


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Jonas Mattisson ◽  
Marcus Danielsson ◽  
Maria Hammond ◽  
Hanna Davies ◽  
Caroline J. Gallant ◽  
...  

AbstractMosaic loss of chromosome Y (LOY) in immune cells is a male-specific mutation associated with increased risk for morbidity and mortality. The CD99 gene, positioned in the pseudoautosomal regions of chromosomes X and Y, encodes a cell surface protein essential for several key properties of leukocytes and immune system functions. Here we used CITE-seq for simultaneous quantification of CD99 derived mRNA and cell surface CD99 protein abundance in relation to LOY in single cells. The abundance of CD99 molecules was lower on the surfaces of LOY cells compared with cells without this aneuploidy in all six types of leukocytes studied, while the abundance of CD proteins encoded by genes located on autosomal chromosomes were independent from LOY. These results connect LOY in single cells with immune related cellular properties at the protein level, providing mechanistic insight regarding disease vulnerability in men affected with mosaic chromosome Y loss in blood leukocytes.


2019 ◽  
Vol 18 (2) ◽  
pp. 1-27 ◽  
Author(s):  
George Lentaris ◽  
Konstantinos Maragos ◽  
Dimitrios Soudris ◽  
Xenophon Zabulis ◽  
Manolis Lourakis

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Tsuyoshi Hachiya ◽  
Takuro Kobayashi ◽  
Wataru Tsutae ◽  
Pamela Hui Peng Gan ◽  
Iri Sato Baran ◽  
...  

AbstractMosaic loss of chromosome Y (mLOY) in leukocytes has attracted much attention as an emerging biomarker of aging and aging-related diseases. We evaluated the usefulness of saliva for mLOY analysis and showed that saliva-derived mLOY is significantly associated with aging and increased physical activity, but not with smoking. While these data support the robust association between saliva-derived mLOY and aging, caution is required when comparing data from saliva-derived and blood-derived mLOY.


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