VBM analysis of white matter volume in children with ametropic amblyopia

2012 ◽  
Author(s):  
Qinying Jiang ◽  
Qian Li ◽  
Mingxia Guo ◽  
Wei Han ◽  
Xiaohui Yin ◽  
...  
Keyword(s):  
White Matter ◽  
White Matter Volume ◽  
Matter Volume

scholarly journals Preliminary Evidence for a Relationship between Elevated Plasma TNFα and Smaller Subcortical White Matter Volume in HCV Infection Irrespective of HIV or AUD Comorbidity

2021 ◽  
Vol 22 (9) ◽  
pp. 4953
Author(s):  
Natalie M. Zahr ◽  
Kilian M. Pohl ◽  
Allison J. Kwong ◽  
Edith V. Sullivan ◽  
Adolf Pfefferbaum
Keyword(s):  
White Matter ◽  
Proinflammatory Cytokines ◽  
Soluble Protein ◽  
Subcortical White Matter ◽  
Control Group ◽  
White Matter Volume ◽  
Brain Volumes ◽  
Protein Levels ◽  
Matter Volume ◽  
Patient Groups

Classical inflammation in response to bacterial, parasitic, or viral infections such as HIV includes local recruitment of neutrophils and macrophages and the production of proinflammatory cytokines and chemokines. Proposed biomarkers of organ integrity in Alcohol Use Disorders (AUD) include elevations in peripheral plasma levels of proinflammatory proteins. In testing this proposal, previous work included a group of human immunodeficiency virus (HIV)-infected individuals as positive controls and identified elevations in the soluble proteins TNFα and IP10; these cytokines were only elevated in AUD individuals seropositive for hepatitis C infection (HCV). The current observational, cross-sectional study evaluated whether higher levels of these proinflammatory cytokines would be associated with compromised brain integrity. Soluble protein levels were quantified in 86 healthy controls, 132 individuals with AUD, 54 individuals seropositive for HIV, and 49 individuals with AUD and HIV. Among the patient groups, HCV was present in 24 of the individuals with AUD, 13 individuals with HIV, and 20 of the individuals in the comorbid AUD and HIV group. Soluble protein levels were correlated to regional brain volumes as quantified with structural magnetic resonance imaging (MRI). In addition to higher levels of TNFα and IP10 in the 2 HIV groups and the HCV-seropositive AUD group, this study identified lower levels of IL1β in the 3 patient groups relative to the control group. Only TNFα, however, showed a relationship with brain integrity: in HCV or HIV infection, higher peripheral levels of TNFα correlated with smaller subcortical white matter volume. These preliminary results highlight the privileged status of TNFα on brain integrity in the context of infection.

Reduced Relationship to Cortical White Matter Volume Revealed by Tractography-Based Segmentation of the Corpus Callosum in Young Children With Developmental Delay

2006 ◽  
Vol 163 (12) ◽  
pp. 2157-2163 ◽  
Author(s):  
Carissa Cascio ◽  
Martin Styner ◽  
Rachel G. Smith ◽  
Michele D. Poe ◽  
Guido Gerig ◽  
...  
Keyword(s):  
White Matter ◽  
Young Children ◽  
Corpus Callosum ◽  
Developmental Delay ◽  
White Matter Volume ◽  
Matter Volume

26.1 GRAY AND WHITE MATTER VOLUME ALTERATIONS IN YOUTH OFFSPRING OF PARENTS WITH BIPOLAR DISORDER

2016 ◽  
Vol 55 (10) ◽  
pp. S298
Author(s):  
Melissa P. DelBello ◽  
Fabiano Nery ◽  
Wade Weber ◽  
Thomas J. Blom ◽  
Jeffrey A. Welge ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
White Matter ◽  
White Matter Volume ◽  
Matter Volume

scholarly journals The relationship between working memory and cerebral white matter volume in survivors of childhood brain tumors treated with conformal radiation therapy

2014 ◽  
Vol 119 (1) ◽  
pp. 197-205 ◽  
Author(s):  
Lisa M. Jacola ◽  
Jason M. Ashford ◽  
Wilburn E. Reddick ◽  
John O. Glass ◽  
Robert J. Ogg ◽  
...  
Keyword(s):  
Working Memory ◽  
Radiation Therapy ◽  
White Matter ◽  
Brain Tumors ◽  
Cerebral White Matter ◽  
White Matter Volume ◽  
Childhood Brain Tumors ◽  
Conformal Radiation Therapy ◽  
Matter Volume ◽  
The Relationship

Gray and white matter volume abnormalities in monozygotic and same-sex dizygotic twins discordant for schizophrenia

2003 ◽  
Vol 60 (1) ◽  
pp. 198
Author(s):  
H. Hulshoff Pol ◽  
R. Brans ◽  
N. Haren ◽  
M. Langen ◽  
H.G. Schnack ◽  
...  
Keyword(s):  
White Matter ◽  
White Matter Volume ◽  
Same Sex ◽  
Matter Volume ◽  
Dizygotic Twins

scholarly journals Neuroanatomy of Patients with Deficit Schizophrenia: An Exploratory Quantitative Meta-Analysis of Structural Neuroimaging Studies

2020 ◽  
Vol 17 (17) ◽  
pp. 6227 ◽  
Author(s):  
Tji Tjian Chee ◽  
Louis Chua ◽  
Hamilton Morrin ◽  
Mao Fong Lim ◽  
Johnson Fam ◽  
...  
Keyword(s):  
White Matter ◽  
Negative Symptoms ◽  
Meta Analysis ◽  
Regions Of Interest ◽  
Grey Matter Volume ◽  
Healthy Controls ◽  
White Matter Volume ◽  
Total Brain Volume ◽  
Matter Volume ◽  
Deficit Schizophrenia

Little is known regarding the neuroanatomical correlates of patients with deficit schizophrenia or persistent negative symptoms. In this meta-analysis, we aimed to determine whether patients with deficit schizophrenia have characteristic brain abnormalities. We searched PubMed, CINAHL and Ovid to identify studies that examined the various regions of interest amongst patients with deficit schizophrenia, patients with non-deficit schizophrenia and healthy controls. A total of 24 studies met our inclusion criteria. A random-effects model was used to calculate a combination of outcome measures, and heterogeneity was assessed by the I2 statistic and Cochran’s Q statistic. Our findings suggested that there was statistically significant reduction in grey matter volume (−0.433, 95% confidence interval (CI): −0.853 to −0.014, p = 0.043) and white matter volume (−0.319, 95% CI: −0.619 to −0.018, p = 0.038) in patients with deficit schizophrenia compared to healthy controls. There is also statistically significant reduction in total brain volume (−0.212, 95% CI: −0.384 to −0.041, p = 0.015) and white matter volume (−0.283, 95% CI: −0.546 to −0.021, p = 0.034) in patients with non-deficit schizophrenia compared to healthy controls. Between patients with deficit and non-deficit schizophrenia, there were no statistically significant differences in volumetric findings across the various regions of interest.

P2-062: Are cerebrospinal fluid levels of neurogranin associated with hippocampal atrophy and brain white matter volume decrease?

2015 ◽  
Vol 11 (7S_Part_11) ◽  
pp. P506-P507
Author(s):  
Simone Lista ◽  
Enrica Cavedo ◽  
Henrik Zetterberg ◽  
Bruno Dubois ◽  
Stéphane Epelbaum ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
White Matter ◽  
Hippocampal Atrophy ◽  
White Matter Volume ◽  
Cerebrospinal Fluid Levels ◽  
Matter Volume ◽  
Brain White Matter ◽  
Fluid Levels ◽  
Volume Decrease

Cerebral gray matter and white matter volume deficits in adolescent girls with anorexia nervosa

1996 ◽  
Vol 129 (6) ◽  
pp. 794-803 ◽  
Author(s):  
Debra K. Katzman ◽  
Evelyn K. Lambe ◽  
David J. Mikulis ◽  
Jeanne N. Ridgley ◽  
David S. Goldbloom ◽  
...  
Keyword(s):  
Anorexia Nervosa ◽  
White Matter ◽  
Adolescent Girls ◽  
Gray Matter ◽  
White Matter Volume ◽  
Matter Volume
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