Short-term reproducibility of the time and frequency domain parameters of heart rate variability

2002 ◽  
Author(s):  
E. Kyrozi ◽  
T. Maounis ◽  
I. Chiladakis ◽  
V. Vassikikos ◽  
A. Manolis ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Frequency Domain ◽  
Short Term

The validity and reliability of ultra-short-term heart rate variability parameters and the influence of physiological covariates

2021 ◽  
Author(s):  
Joel S. Burma ◽  
Sarah Graver ◽  
Lauren N. Miutz ◽  
Alannah Macaulay ◽  
Paige V. Copeland ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Frequency Domain ◽  
Repeated Measures ◽  
Intraclass Correlation ◽  
Correlation Coefficients ◽  
Validity And Reliability ◽  
Short Term ◽  
Physiological Variables ◽  
Orthostatic Position

Background: Ultra-short-term (UST) heart rate variability (HRV) metrics have increasingly been proposed as surrogates for short-term HRV metrics. However, the concurrent validity, within-day reliability, and between-day reliability of UST HRV have yet to be comprehensively documented. Methods: Thirty-six adults (18 males, age: 26 ± 5 years, BMI: 24 ± 3 kg/m2) were recruited. Measures of HRV were quantified in a quiet-stance upright orthostatic position via three-lead electrocardiogram (ADInstruments, FE232 BioAmp). All short-term data recordings were 300-seconds in length and five UST time points (i.e., 30-seconds, 60-seconds, 120-seconds, 180-seconds, and 240-seconds) were extracted from the original 300-second recording. Bland-Altman plots with 95% limits of agreement, repeated measures ANOVA, and two-tailed paired t-tests demarcated differences between UST and short-term recordings. Linear regressions, coefficient of variation, intraclass correlation coefficients, and other tests examined the validity and reliability in both time- and frequency-domains. Results: No group differences were noted between all short-term and UST measures, for either time- (all p>0.202) or frequency-domain metrics (all p>0.086). A longer recording duration was associated with augmented validity and reliability, that was less impacted by confounding influences from physiological variables (e.g., respiration rate, carbon dioxide end-tidals, and blood pressure). Conclusively, heart rate, time-domain, and relative frequency-domain HRV metrics were acceptable with recordings greater or equal to 60s, 240s, and 300s, respectively. Conclusions: Future studies employing UST HRV metrics, should thoroughly understand the methodological requirements to obtain accurate results. Moreover, a conservative approach should be utilized regarding the minimum acceptable recording duration, which ensures valid/reliable HRV estimates are obtained.

scholarly journals Short-term Heart Rate Variability Analysis in Healthy Dogs of Different Ages

2022 ◽  
Vol 50 ◽  
Author(s):  
Luciene Maria Martinello Romão ◽  
Amanda Sarita Cruz Aleixo ◽  
Felipe Gazza Romão ◽  
Mayra De Castro Ferreira Lima ◽  
Miriam Tsunemi ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Frequency Domain ◽  
Time Domain ◽  
Age Groups ◽  
The Other ◽  
Short Term ◽  
Heart Rate Monitor ◽  
Rr Intervals ◽  
Healthy Dogs

Background: The modulation of heart rate by autonomic nervous system may be evaluated by the heart rate variability (HRV), which illustrates the fluctuations between RR intervals. To evaluate this analysis, the intervals between 2 QRS complexes are measured. In general, high HRV values are expected in healthy individuals; otherwise, low values are indicative of organism dysfunction. Studies conducted in healthy humans show that HRV suffers reduction with ageing and that there is autonomic immaturity in neonates. The aim of this study was to describe the characteristic pattern of cardiac autonomic behavior in healthy dogs in different age groups through short-term HRV analysis.Materials, Methods & Results: A total of 87 healthy dogs were studied. HRV was analyzed in time and frequency domain, using Holter and heart rate monitor. It was observed that puppies (below one year old) presented a lower parasympathetic predominance and, consequently, lower HRV values on time domain (SDNN, PNN50% e RMSSD) compared to the other 2 groups and on frequency domain (LF, HF and LF/HF) compared to the adult animals group (between 1 and 7-year-old), which presented higher HRV values when compared to the other groups. Elderly dogs (over 8-year-old) exhibited a natural tendency to decrease cardiac parasympathetic HRV indexes.Discussion: The use of the HRV method as a prognostic index and as an arrhythmogenic marker for various canine heart diseases presents interesting perspectives. However, before it may be employed for these purposes, a better understanding should be established regarding the physiological behavior of autonomic cardiac modulation in different age groups to serve as a basis for future analyses. This study observed that puppies presented higher values for HR and, therefore, shorter RR intervals than the other groups (adult and elderly dogs), what was observed on Holter and heart rate monitor methods (HRM). There were significant differences between puppies and the other 2 groups (adults and elderly) for all time-domain variables using both methods (Holter and HRM methods). SDNN was significantly lower in puppies compared to adults and elderly dogs. In addition, both RMSSD and PNN50%, which were more reliable over shorter periods of time, also presented means and medians that were significantly lower in puppies. Regarding frequency-domain HRV parameters observed on Holter method, these indexes were decreased on the elderly group compared to adult dogs, which is a possible effect of aging. Also, puppies revealed lower frequency-domain HRV parameters on both methods when compared to adult dogs. The influence of age on HRV is possibly related to the stage of development of an individual, starting at conception up to the maturity in relation to the mechanisms that cause variations in HR. There are studies in humans that suggest a gradual increase in parasympathetic activity during childhood, followed by a steady decrease as aging occur. The present study observed the same pattern in dogs. The balance between sympathetic and parasympathetic systems is influenced by age in dogs, which alters HRV values in the short-term. The HRV method´s analysis is relatively simple and non-invasive for assessing cardiac autonomic function; also, it is widely used in human medicine as a risk measure for sudden cardiac death. The 24-hour HRV analysis is highly challenging, as it is time-consuming, expensive, delays diagnosis, and has a large number of artifacts; in this way, standards for its short-term analysis were developed. Keywords: cardiology, autonomic nervous system, heart rate monitor, Holter.

scholarly journals Daily Food Insecurity and Heart Rate Variability Among Healthy Low-Income Adults: A Longitudinal Pilot Study Over Two Seasonal Months

2021 ◽  
Vol 5 (Supplement_2) ◽  
pp. 118-118
Author(s):  
Nan Dou ◽  
Muzi Na
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Pilot Study ◽  
Food Insecurity ◽  
Frequency Domain ◽  
Low Income ◽  
Time Domain ◽  
Time Varying ◽  
Short Term ◽  
Stress Vulnerability

Abstract Objectives Food insecurity (FI) is prevalent among low-income adults and is related to increased stress. Heart rate variability (HRV) is associated with adverse health and a known indicator for stress vulnerability. However, the relationship between FI and HRV is unclear. Our study aims to study the associations between FI and ultra-short-term HRV (5 minutes) at daily basis. Methods A total of 22 healthy low-income adults were recruited in fall 2019 and 18 were followed up in winter 2020. Data on FI and HRV were collected over a 3-week-long wave in each surveyed month (2nd – 4th week). Daily FI was assessed using the adapted USDA adult module on the provided smartphones. Each day, a 5-minute heart rate was recorded using the Polar H7 sensor, yielding a number of HRV metrics in two domains. SDNN, Rmssd, and pNN50 are time-domain metrics quantifying the amount of variability in interbeat interval (the higher the ‘better’). LF/HF Ratio is a frequency-domain metrics estimating the distribution of power into frequency bands (the lower the ‘better’). The Time Varying Effect Models were used to estimate the association between daily FI and ultra-short-term HRV metrics as a function of study day. Results A total of 606 person-days (response rate = 72.1%) of data in FI and HRV was collected. In fall, higher FI score was significantly associated with lower lnRmssd at day 19 (b = −0.13) and 20 (b = −0.12), lower Pnn50 at day 20 (b = −0.13), and higher LF/HF ratio from day 1 to 5 (b ranges 0.29–0.88). In winter, higher FI score was related to lower lnRmssd at day 18 (b = −0.24) and 19 (b = −0.27), lower Pnn50 from day 17 to 19 (b ranges −10.99 to −7.79), and higher LF/HF ratio from day 9 to 11 (b ranges 0.78–1.22) and day 18 to 20 (b ranges 1.17–2.40). Conclusions Across the 2 months spanning two seasons, our pilot study found that daily FI was significantly and consistently associated with suboptimal time-domain HRV metrics in the last few days of the study months. Results for the frequency-domain also support a time-varying impact of FI on HRV. The preliminary results support a potential more profound impact of FI on stress vulnerability, particularly by the end of the months. Funding Sources The National Center for Advancing Translational Sciences, National Institutes of Health (UL1TR002014) and the Broadhurst Career Development Professorship for the Study of Health Promotion and Disease Prevention.

scholarly journals Diet-Induced Metabolic Syndrome Reduced Heart Rate Variability and Increased Irregularity and Complexity of Short-Term RR Time Series in Rabbits

Animals ◽  
2019 ◽  
Vol 9 (8) ◽  
pp. 572 ◽  
Author(s):  
Wilson Lozano ◽  
Conrado Calvo ◽  
Oscar Arias-Mutis ◽  
Ana Díaz ◽  
Luis Such-Miquel ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Heart Rate ◽  
Time Series ◽  
Heart Rate Variability ◽  
Frequency Domain ◽  
Time Domain ◽  
Rabbit Model ◽  
Low Frequency ◽  
Nonlinear Analyses ◽  
Short Term

Metabolic syndrome (MetS) has been linked to a higher prevalence of sudden cardiac death (SCD), but the mechanisms are not well understood. One possible underlying mechanism may be an abnormal modulation of autonomic activity, which can be quantified by analyzing heart rate variability (HRV). Our aim was to investigate the modifications of short-term HRV in an experimental rabbit model during the time-course of MetS development. NZW rabbits were randomly assigned to a control (n = 10) or a MetS group (n = 13), fed 28 weeks with control or high-fat, high-sucrose diets. After anesthesia, a 15-min ECG recording was acquired before diet administration and at weeks 14 and 28. We analyzed short RR time series using time-domain, frequency-domain and nonlinear analyses. A mixed-model factorial ANOVA was used for statistical analysis. Time-domain analysis showed a 52.4% decrease in the standard deviation of heart rate in animals from the MetS group at week 28, but no changes in the rest of parameters. In the frequency domain, we found a 9.7% decrease in the very low frequency and a 380.0% increase of the low frequency bands in MetS animals at week 28, whereas high frequency remained unchanged. Nonlinear analyses showed increased complexity and irregularity of the RR time series in MetS animals.

Algogen-induced vasosensory reflexes modulate short-term heart rate variability parameters in experimental rat models

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Ravindran Revand ◽  
Sanjeev K. Singh
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Frequency Domain ◽  
Time Domain ◽  
Inflammatory Mediators ◽  
Saline Control ◽  
Short Term ◽  
Rat Models ◽  
Reflex Responses

Abstract Objectives The present work was designed to study the modulatory effects of algogen-induced vasosensory reflex responses on short-term heart rate variability (HRV) parameters in naïve and vagotomized rat models. Methods In this study, vasosensory reflex responses were elicited by instilling algogens (bradykinin/histamine), a component of inflammatory mediators into a local segment of medium-sized peripheral blood vessel (femoral artery) while a continuous electrocardiogram (ECG) was recorded. Short-term (5 min) ECG segments obtained from original recordings were examined in detail and relevant data of HRV parameters were pooled. Time domain and frequency domain analyses were performed using dedicated software (LabChart 8, AD Instruments®, Australia) and results were analyzed. Results Bradykinin-induced vasosensory reflexes caused significant alterations in both time domain and frequency domain HRV parameters as compared to the time-matched saline control group. Instillation of bradykinin caused a transient increase in NN interval, RMSSD, TSP, HF power (HFP) along with a decrease in the standard deviation of all normal NN intervals (SDNN), SDNN/RMSSD, LF power (LFP), LFP/HFP. Histamine produced a similar pattern of responses, but HRV alterations were less pronounced compared to those with bradykinin. Further analysis revealed that algogen-induced vasosensory reflex responses caused an increase in the parasympathetic influence on the heart accompanied by a decrease in sympathetic influence. In addition, HRV modulation by algogen-induced vasosensory reflexes was significantly attenuated in vagotomized rats, illustrating the principal role of vagus in the reflex HRV modulation. Conclusions The present study proposes a novel hypothesis regarding the cardio-protective role of inflammatory mediators during acute stress, by potentiating the vagal impact and attenuating the sympathetic impact on the heart.

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