Machine learning algorithm to predict coronary artery calcification in asymptomatic healthy population

Author(s):  
Kranthi K Kolli ◽  
Sung Hak Park ◽  
James K. Min ◽  
Hyuk-Jae Chang ◽  
Donghee Han ◽  
...  
RSC Advances ◽  
2020 ◽  
Vol 10 (7) ◽  
pp. 4014-4022
Author(s):  
Young Woo Kim ◽  
Hee-Jin Yu ◽  
Jung-Sun Kim ◽  
Jinyong Ha ◽  
Jongeun Choi ◽  
...  

A two-step machine learning (ML) algorithm for coronary artery decision making is introduced, to increase the data quality by providing flow characteristics and biometric features by aid of computational fluid dynamics (CFD).


Antioxidants ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 1132
Author(s):  
Youjin Kim ◽  
Yunsoo Kim ◽  
Jiyoung Hwang ◽  
Tim J. van den Broek ◽  
Bumjo Oh ◽  
...  

Oxidative stress aggravates the progression of lifestyle-related chronic diseases. However, knowledge and practices that enable quantifying oxidative stress are still lacking. Here, we performed a proof-of-concept study to predict the oxidative stress status in a healthy population using retrospective cohort data from Boramae medical center in Korea (n = 1328). To obtain binary performance measures, we selected healthy controls versus oxidative disease cases based on the “health space” statistical methodology. We then developed a machine learning algorithm for discrimination of oxidative stress status using least absolute shrinkage and selection operator (LASSO)/elastic net regression with 10-fold cross-validation. A proposed fine-tune model included 16 features out of the full spectrum of diverse and complex data. The predictive performance was externally evaluated by generating receiver operating characteristic curves with area under the curve of 0.949 (CI 0.925 to 0.974), sensitivity of 0.923 (CI 0.879 to 0.967), and specificity of 0.855 (CI 0.795 to 0.915). Moreover, the discrimination power was confirmed by applying the proposed diagnostic model to the full dataset consisting of subjects with various degrees of oxidative stress. The results provide a feasible approach for stratifying the oxidative stress risks in the healthy population and selecting appropriate strategies for individual subjects toward implementing data-driven precision nutrition.


2018 ◽  
Vol 45 (5) ◽  
pp. 901-910 ◽  
Author(s):  
Shaik Mohammad Naushad ◽  
Tajamul Hussain ◽  
Bobbala Indumathi ◽  
Khatoon Samreen ◽  
Salman A. Alrokayan ◽  
...  

2018 ◽  
Author(s):  
C.H.B. van Niftrik ◽  
F. van der Wouden ◽  
V. Staartjes ◽  
J. Fierstra ◽  
M. Stienen ◽  
...  

Author(s):  
Kunal Parikh ◽  
Tanvi Makadia ◽  
Harshil Patel

Dengue is unquestionably one of the biggest health concerns in India and for many other developing countries. Unfortunately, many people have lost their lives because of it. Every year, approximately 390 million dengue infections occur around the world among which 500,000 people are seriously infected and 25,000 people have died annually. Many factors could cause dengue such as temperature, humidity, precipitation, inadequate public health, and many others. In this paper, we are proposing a method to perform predictive analytics on dengue’s dataset using KNN: a machine-learning algorithm. This analysis would help in the prediction of future cases and we could save the lives of many.


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