scholarly journals Automated characterization of gene expression patterns with an atlas of the mouse brain

Author(s):  
J.P. Carson ◽  
T. Ju ◽  
C. Thaller ◽  
J. Warren ◽  
M. Bello ◽  
...  
Biomolecules ◽  
2020 ◽  
Vol 10 (2) ◽  
pp. 327 ◽  
Author(s):  
Qiang Zhang ◽  
Lan Shen ◽  
Deyong Ren ◽  
Jiang Hu ◽  
Li Zhu ◽  
...  

The chloroplast RNA splicing and ribosome maturation (CRM) domain-containing proteins regulate the expression of chloroplast or mitochondrial genes that influence plant growth and development. Although 14 CRM domain proteins have previously been identified in rice, there are few studies of these gene expression patterns in various tissues and under abiotic stress. In our study, we found that 14 CRM domain-containing proteins have a conservative motif1. Under salt stress, the expression levels of 14 CRM genes were downregulated. However, under drought and cold stress, the expression level of some CRM genes was increased. The analysis of gene expression patterns showed that 14 CRM genes were expressed in all tissues but especially highly expressed in leaves. In addition, we analyzed the functions of OsCFM2 and found that this protein influences chloroplast development by regulating the splicing of a group I and five group II introns. Our study provides information for the function analysis of CRM domain-containing proteins in rice.


2015 ◽  
Vol 112 (32) ◽  
pp. 9920-9925 ◽  
Author(s):  
Owen Marecic ◽  
Ruth Tevlin ◽  
Adrian McArdle ◽  
Eun Young Seo ◽  
Taylor Wearda ◽  
...  

The postnatal skeleton undergoes growth, remodeling, and repair. We hypothesized that skeletal progenitor cells active during these disparate phases are genetically and phenotypically distinct. We identified a highly potent regenerative cell type that we term the fracture-induced bone, cartilage, stromal progenitor (f-BCSP) in the fracture callus of adult mice. The f-BCSP possesses significantly enhanced skeletogenic potential compared with BCSPs harvested from uninjured bone. It also recapitulates many gene expression patterns involved in perinatal skeletogenesis. Our results indicate that the skeletal progenitor population is functionally stratified, containing distinct subsets responsible for growth, regeneration, and repair. Furthermore, our findings suggest that injury-induced changes to the skeletal stem and progenitor microenvironments could activate these cells and enhance their regenerative potential.


Methods ◽  
2010 ◽  
Vol 50 (2) ◽  
pp. 85-95 ◽  
Author(s):  
James Carson ◽  
Tao Ju ◽  
Musodiq Bello ◽  
Christina Thaller ◽  
Joe Warren ◽  
...  

2014 ◽  
Vol 220 (5) ◽  
pp. 2691-2703 ◽  
Author(s):  
Tao Zeng ◽  
Hanbo Chen ◽  
Ahmed Fakhry ◽  
Xiaoping Hu ◽  
Tianming Liu ◽  
...  

2010 ◽  
Vol 107 (44) ◽  
pp. 19049-19054 ◽  
Author(s):  
J. A. Morris ◽  
J. J. Royall ◽  
D. Bertagnolli ◽  
A. F. Boe ◽  
J. J. Burnell ◽  
...  

2005 ◽  
Vol 102 (29) ◽  
pp. 10357-10362 ◽  
Author(s):  
M. A. Zapala ◽  
I. Hovatta ◽  
J. A. Ellison ◽  
L. Wodicka ◽  
J. A. Del Rio ◽  
...  

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