Temporal and spatial gene expression patterns after experimental stroke in a rat model and characterization of PC4, a potential regulator of transcription

The chloroplast RNA splicing and ribosome maturation (CRM) domain-containing proteins regulate the expression of chloroplast or mitochondrial genes that influence plant growth and development. Although 14 CRM domain proteins have previously been identified in rice, there are few studies of these gene expression patterns in various tissues and under abiotic stress. In our study, we found that 14 CRM domain-containing proteins have a conservative motif1. Under salt stress, the expression levels of 14 CRM genes were downregulated. However, under drought and cold stress, the expression level of some CRM genes was increased. The analysis of gene expression patterns showed that 14 CRM genes were expressed in all tissues but especially highly expressed in leaves. In addition, we analyzed the functions of OsCFM2 and found that this protein influences chloroplast development by regulating the splicing of a group I and five group II introns. Our study provides information for the function analysis of CRM domain-containing proteins in rice.

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Different Temporal and Spatial Gene Expression Patterns Occur during Anther Development.

The Plant Cell ◽

10.1105/tpc.2.12.1201 ◽

1990 ◽

pp. 1201-1224 ◽

Cited By ~ 389

Author(s):

A. M. Koltunow ◽

J. Truettner ◽

K. H. Cox ◽

M. Wallroth ◽

R. B. Goldberg

Keyword(s):

Gene Expression ◽

Expression Patterns ◽

Anther Development ◽

Gene Expression Patterns ◽

Temporal And Spatial

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Identification and characterization of an injury-induced skeletal progenitor

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.1513066112 ◽

2015 ◽

Vol 112 (32) ◽

pp. 9920-9925 ◽

Cited By ~ 54

Author(s):

Owen Marecic ◽

Ruth Tevlin ◽

Adrian McArdle ◽

Eun Young Seo ◽

Taylor Wearda ◽

...

Keyword(s):

Gene Expression ◽

Progenitor Cells ◽

Expression Patterns ◽

Gene Expression Patterns ◽

Cell Type ◽

Fracture Callus ◽

Adult Mice ◽

Induced Changes ◽

Identification And Characterization

The postnatal skeleton undergoes growth, remodeling, and repair. We hypothesized that skeletal progenitor cells active during these disparate phases are genetically and phenotypically distinct. We identified a highly potent regenerative cell type that we term the fracture-induced bone, cartilage, stromal progenitor (f-BCSP) in the fracture callus of adult mice. The f-BCSP possesses significantly enhanced skeletogenic potential compared with BCSPs harvested from uninjured bone. It also recapitulates many gene expression patterns involved in perinatal skeletogenesis. Our results indicate that the skeletal progenitor population is functionally stratified, containing distinct subsets responsible for growth, regeneration, and repair. Furthermore, our findings suggest that injury-induced changes to the skeletal stem and progenitor microenvironments could activate these cells and enhance their regenerative potential.

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