MusiKeys: Investigating Auditory-Physical Feedback Replacement Technique for Mid-air Typing

Author(s):  
Alexander Krasner ◽  
Joseph L. Gabbard ◽  
Gary Burnett
Author(s):  
Robert A. Grant ◽  
Laura L. Degn ◽  
Wah Chiu ◽  
John Robinson

Proteolytic digestion of the immunoglobulin IgG with papain cleaves the molecule into an antigen binding fragment, Fab, and a compliment binding fragment, Fc. Structures of intact immunoglobulin, Fab and Fc from various sources have been solved by X-ray crystallography. Rabbit Fc can be crystallized as thin platelets suitable for high resolution electron microscopy. The structure of rabbit Fc can be expected to be similar to the known structure of human Fc, making it an ideal specimen for comparing the X-ray and electron crystallographic techniques and for the application of the molecular replacement technique to electron crystallography. Thin protein crystals embedded in ice diffract to high resolution. A low resolution image of a frozen, hydrated crystal can be expected to have a better contrast than a glucose embedded crystal due to the larger density difference between protein and ice compared to protein and glucose. For these reasons we are using an ice embedding technique to prepare the rabbit Fc crystals for molecular structure analysis by electron microscopy.


1993 ◽  
Vol 06 (02) ◽  
pp. 85-92 ◽  
Author(s):  
G. L. Coetzee

SummaryThe immediate postoperative biomechanical properties of an “underand-over” cranial cruciate ligament (CCL) replacement technique consisting of fascia lata and the lateral onethird of the patellar ligament, were compared with that of a modified intra- and extracapsular “under-and-over-the-top” (UOTT) method. The right CCL in twelve adult dogs was dissected out and replaced with an autograft. The contralateral, intact CCL served as the control. In group A, the graft was secured to the lateral femoral condyle with a spiked washer and screw. In group B the intracapsular graft was secured to the lateral femoro-fabellar ligament, and the remainder to the patellar tendon. Both CCL replacement techniques exhibited a 2.0 ± 0.5 mm anterior drawer immediately after the operation. After skeletonization of the stifles, the length and cross-sectional area of the intact CCL and CCL substitutes were determined. Each bone-ligament unit was tested in linear tension to failure at a fixed distraction rate of 15 mm/s with the stifle in 120° flexion. Data was processed to obtain the corresponding material parameters (modulus, stress and strain in the linear loading region, and energy absorption to maximum load).The immediate postoperative structural and material properties of the “under-and-over” cranial cruciate ligament replacement technique with autogenous fascia lata, were compared to that of a modified intra- and extracapsular “under-and-over-the-top” (UOTT) method. The combined UOT T technique was slightly stronger (6%), but allowed 2.8 ± 0.9 mm more cranial tibial displacement at maximum linear force.


1981 ◽  
Vol 52 (2) ◽  
pp. 359-362 ◽  
Author(s):  
Frederick J. Klopfer ◽  
Thomas T. Jackson

In a rejoinder, Kuethe (1980) criticized an article by Jackson and Klopfer (1977) which found no differences in the replacement accuracy of human and non-human figures on the Felt Figure Replacement Technique. The present reply gives primarily an analysis of those studies suggested by Kuethe as supporting his position and shows weak or non-existent support. This reply also examines the supposed ignoring of ordinal data patterns and finds no support for such criticism. The sensory-perceptual explanation supported by Jackson and Klopfer (1977) and others remains a viable alternative to the social-perceptual explanation provided by Kuethe.


2014 ◽  
Vol 128 (12) ◽  
pp. 1050-1055 ◽  
Author(s):  
M Malhotra ◽  
S Varshney ◽  
R Malhotra

AbstractObjective:To develop an autologous total ossicular replacement prosthesis with sustainable hearing results.Methods:The ears of 40 patients, who had chronic otitis media with absent suprastructure of the stapes and long process of the incus, were repaired using the autologous total ossicular replacement technique. Post-operative results were evaluated after 6 and 12 months on the basis of average pure tone air conduction and average air–bone gap measured at 0.5, 1, 2 and 3 kHz.Results:Successful rehabilitation of pure tone average to 30 dB or less was achieved in 75 per cent of patients, and air–bone gap to 20 dB or less was attained in 82.5 per cent of patients. Overall mean improvement in air–bone gap was 23.9 ± 8.5 dB (p < 0.001). Mean improvements in air–bone gap were significantly greater (p < 0.05) in the tympanoplasty only group (27.3 ± 6.6 dB) and the intact canal wall tympanoplasty group (25.9 ± 6.3 dB) than in the canal wall down tympanoplasty group (16.3 ± 8.9 dB).Conclusion:This paper describes an autologous total ossicular replacement prosthesis that is biocompatible, stable, magnetic resonance imaging compatible and, above all, results in sustainable hearing improvement.


2013 ◽  
Vol 845 ◽  
pp. 403-407
Author(s):  
Natesan Dhandapani ◽  
A. Gnanavelbabu ◽  
M. Sivasankar

In this changing global scenario, modification, transplantation, and replacement can be the eternal solution for most of the problems in the medical field. Hence replacement technique finds a very prominent place in medicine as a remedy having closely tied up with biomechanics. One of the most important joints in the human body is the hip joint, the big and complex joint. Many researches were conducted and many are in progress, but most of these works use simplified models with either 2D or 3D approaches. The hip joint is formed by four components like femoral head cortical bone, stem, and neck. In this system we can find orthotropic and isotropic materials working together. The main objective of this research is to develop a three dimensional surface and solid finite element model of the hip joint to predict stresses in its individual components. This model is a geometric non-linear model, which helps us understand its structural mechanical behavior, seeming to suggest with advanced research in the future new hip joint prosthesis, as well as to prove the prosthesis joint interaction before being implanted in the patient. This research explains a complete human hip joint model without cartilaginous tissue, using ANSYS 10.0 Multiphysics Analysis for nine different postures in hip joint using three different materials (CoCr, Ti6Al4V, and UHMWPE) to calculate fatigue life. The result obtained from the analysis of surface model and solid model serve to help in predicting the life cycle, surface characteristics, shear stress in XY plane, stress concentration and areas that are prone to failure. Von Mises stress on the surface of our model facilitates us to equip and design an optimized prosthesis device having unique materials composition , with a highly bio-compatible and durable alloy at a low cost could be produced. In this way, a first important step towards the structural characterization of human hip joint has been developed.


2017 ◽  
Vol 41 (4) ◽  
pp. 610-617 ◽  
Author(s):  
Gianpaolo Carrafiello ◽  
Andrea Coppola ◽  
Giuseppe De Marchi ◽  
Federico Fontana ◽  
Filippo Piacentino ◽  
...  

2018 ◽  
Vol 162 ◽  
pp. 01020 ◽  
Author(s):  
Nahla Salim ◽  
Kawther Al-Soudany ◽  
Nora Jajjawi

All structures built on soft soil may experience uncontrollable settlement and critical bearing capacity. This may not meet the design requirements for the geotechnical engineer. Soil stabilization is the change of these undesirable properties in order to meet the requirements. Traditional methods of stabilizing or through in-situ ground improvement such as compaction or replacement technique is usually costly. Now a safe and economic disposal of industrial wastes and development of economically feasible ground improvement techniques are the important challenges being faced by the engineering community. This work focuses on improving the soft soil brought from Baghdad by utilizing the local waste material for stabilization of soil, such as by using “Nylon carry bag’s by product” with the different percentage and corresponding to 1 %, 3% and 5% (the portion of stabilizer matters to soil net weight) of dried soil. The results indicated that as Nylon’s fiber content increases, the liquid limit decreases while the plastic limit increases, so the plasticity index decreases. Furthermore, the maximum dry density decreases while, the optimum moisture content increases as the Nylon’s fiber percentage increases. The compression index (decreases as the Nylon’s fiber increases and provides a maximum of 43% reduction by adding 5% nylon waste material. In addition, the results indicated that, the undrained shear strength increases as the nylon fiber increases.


2005 ◽  
Vol 12C (3) ◽  
pp. 331-338
Author(s):  
Byung Ryong Kim ◽  
Ki Chang Kim

2014 ◽  
Vol 46 (6) ◽  
pp. 944-951 ◽  
Author(s):  
Denis A. Berdajs ◽  
Mirza Muradbegovic ◽  
Daniel Haselbach ◽  
Reto Kofmehl ◽  
Johann Steurer ◽  
...  

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