Signal amplification based on a polymeric film decorated with nanocomposites for sensitive determination of propranolol in biological and pharmaceutical samples

2021 ◽  
pp. 1-1
Author(s):  
Fatemeh Mortazavi ◽  
Nastaran Arab ◽  
Lida Fotouhi
Keyword(s):  
Signal Amplification ◽  
Polymeric Film ◽  
Pharmaceutical Samples ◽  
Sensitive Determination

A ratiometric electrochemical strategy for sensitive determination of Furin activity based on dual signal amplification and antifouling nanosurfaces

The Analyst ◽  
2017 ◽  
Vol 142 (22) ◽  
pp. 4215-4220 ◽  
Author(s):  
Dazhi Yao ◽  
Wenqi Zhao ◽  
Limin Zhang ◽  
Yang Tian
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cell Surface ◽  
Signal Amplification ◽  
Accurate Method ◽  
Sensitive Determination ◽  
Dual Signal Amplification

Developing a sensitive and accurate method for Furin activity is still the bottleneck for understanding the role played by Furin in cell-surface systems and even in Alzheimer's disease.

scholarly journals Signal amplification for sumatriptan sensing based on polymeric surface decorated with Cu nanoparticles

2018 ◽  
Vol 83 (4) ◽  
pp. 449-462
Author(s):  
Ghasem Karim-Nezhad ◽  
Samane Khanaliloo ◽  
Zeynab Khorablou ◽  
Seyed Dorraji
Keyword(s):  
Signal Amplification ◽  
Biological Fluids ◽  
Differential Pulse ◽  
Cu Nanoparticles ◽  
Linear Calibration ◽  
Polymeric Surface ◽  
Sensitive Determination ◽  
Pulse Voltammetry ◽  
Uniform Deposition

A new nanocomposite, Cu NPs/poly-melamine, was deposited on a glassy carbon electrode by cyclic voltammetry. The uniform deposition of the nanocomposite was observed by the field emission scanning electron microscopy. The electron transfer characteristics of the drug sumatriptan (SUM), was greatly improved on the modified electrode. The prepared electrode was used for the sensitive determination of SUM by the differential pulse voltammetry. Linear calibration curve was obtained in the concentration ranges of 0.08?0.58 and 0.58?6.5 ?M, and the detection limit of 0.025 ?M. The proposed method was evaluated by the determination of SUM in human biological fluids such as urine and blood plasma with satisfactory results (recovery > 99 %).

Sign in / Sign up

Export Citation Format

Share Document