Highly Sensitive DNA Detection Beyond the Debye Screening Length using CMOS Field Effect Transistors

2021 ◽  
pp. 1-1
Author(s):  
Yi-Wei Chen ◽  
Michael S.-C. Lu
Nano Letters ◽  
2007 ◽  
Vol 7 (11) ◽  
pp. 3405-3409 ◽  
Author(s):  
Eric Stern ◽  
Robin Wagner ◽  
Fred J. Sigworth ◽  
Ronald Breaker ◽  
Tarek M. Fahmy ◽  
...  

2009 ◽  
Vol 2009 ◽  
pp. 1-5 ◽  
Author(s):  
Satyabrata Sahoo ◽  
Y. K. Ho

The plasma screening effect is found to uncover a Cooper minimum in the photoionization cross sections from the ground state of the Li atom embedded in Debye plasma environment. The variation of the location of this minimum with Debye screening length is discussed and analyzed in terms of the instability of the ground state.


Science ◽  
2018 ◽  
Vol 362 (6412) ◽  
pp. 319-324 ◽  
Author(s):  
Nako Nakatsuka ◽  
Kyung-Ae Yang ◽  
John M. Abendroth ◽  
Kevin M. Cheung ◽  
Xiaobin Xu ◽  
...  

Detection of analytes by means of field-effect transistors bearing ligand-specific receptors is fundamentally limited by the shielding created by the electrical double layer (the “Debye length” limitation). We detected small molecules under physiological high–ionic strength conditions by modifying printed ultrathin metal-oxide field-effect transistor arrays with deoxyribonucleotide aptamers selected to bind their targets adaptively. Target-induced conformational changes of negatively charged aptamer phosphodiester backbones in close proximity to semiconductor channels gated conductance in physiological buffers, resulting in highly sensitive detection. Sensing of charged and electroneutral targets (serotonin, dopamine, glucose, and sphingosine-1-phosphate) was enabled by specifically isolated aptameric stem-loop receptors.


2010 ◽  
Vol 22 (46) ◽  
pp. 5297-5300 ◽  
Author(s):  
Rory Stine ◽  
Jeremy T. Robinson ◽  
Paul E. Sheehan ◽  
Cy R. Tamanaha

Materials ◽  
2018 ◽  
Vol 11 (12) ◽  
pp. 2550 ◽  
Author(s):  
Konstantin Tretiakov ◽  
Paweł Pigłowski ◽  
Jakub Narojczyk ◽  
Mikołaj Bilski ◽  
Krzysztof Wojciechowski

Computer simulations using Monte Carlo method in the isobaric-isothermal ensemble were used to investigate the impact of nanoinclusions in the form of very narrow channels in the [ 111 ] -direction on elastic properties of crystals, whose particles interact via Yukawa potential. The studies were performed for several selected values of Debye screening length ( ( κ σ ) − 1 ). It has been observed that introduction of the nanoinclusions into the system reduces the negative value of Poisson’s ratio towards [ 110 ] [ 1 1 ¯ 0 ] , maintaining practically constant values of Poisson’s ratio in the directions [ 100 ] and [ 111 ] . These studies also show that concentration of particles forming the nanoinclusions in the system has a significant effect on the value of Poisson’s ratio in the [ 110 ] [ 1 1 ¯ 0 ] -direction. A strong (more than fourfold) decrease of Poisson’s ratio in this direction was observed, from − 0.147 ( 3 ) (system without inclusions) to − 0.614 ( 14 ) (system with nanoinclusions) at κ σ = 10 when the inclusion particles constituted about 10 percent of all particles. The research also showed an increase in the degree of auxeticity in the system with increasing concentration of nanoinclusion particles for all the screening lengths considered.


1978 ◽  
Vol 55 (2) ◽  
pp. 377-379 ◽  
Author(s):  
N. Radić ◽  
S. Marčelja

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