A high detection efficiency BGO, flow-through, coincidence detection system for arterial blood sampling with PET: application and dispersion correction for small animal PET studies

2002 ◽  
Author(s):  
H. Tadokoro ◽  
K. Yoshida ◽  
A. Takami ◽  
K. Shimada ◽  
S. Kitsukawa ◽  
...  
Keyword(s):  
Detection Efficiency ◽  
Detection System ◽  
Small Animal ◽  
Coincidence Detection ◽  
Small Animal Pet ◽  
Dispersion Correction ◽  
Arterial Blood ◽  
High Detection ◽  
High Detection Efficiency ◽  
Flow Through

scholarly journals Simulation study of a coincidence detection system for non-invasive determination of arterial blood time-activity curve measurements

2020 ◽  
Author(s):  
Yassine Toufique ◽  
Othmane Bouhali ◽  
Pauline Negre ◽  
Jim O Doherty
Keyword(s):  
Activity Concentration ◽  
Detection Efficiency ◽  
Detection System ◽  
Coincidence Detection ◽  
Time Activity ◽  
Time Activity Curve ◽  
Non Invasive ◽  
Arterial Blood ◽  
Arterial Sampling ◽  
Activity Curve

Abstract Background : Arterial sampling in PET studies for the purposes of kinetic modeling remains an invasive, time intensive and expensive procedure. Alternatives to derive the blood time-activity curve (BTAC) non-invasively are either reliant on large vessels in the field of view or are laborious to implement and analyse as well as being prone to many processing errors. An alternative method is proposed in this work by the simulation of a non-invasive coincidence detection unit. Results: We utilized GATE simulations of a human forearm phantom with a blood flow model, as well as a model for dynamic radioactive bolus activity concentration based on clinical measurements. A fixed configuration of 14, and also separately, 8 detectors were employed around the phantom, and simulations performed to investigate signal detection parameters. BGO crystals proved to show the highest detection efficiency and sensitivity to a simulated BTAC with a maximum coincidence rate of 575 cps. Repeatable location of the blood vessels in the forearm allowed a half-ring design with only 8 detectors. Using this configuration, maximum coincident rates of 250 cps and 42 cps were achieved with simulation of activity concentration determined from 15 O and 18 F arterial blood sampling. NECR simulated in a water phantom at 3 different vertical positions inside the 8-detector system (Y=-1 cm, Y=-2 cm and Y=-3 cm) was 8360 cps, 13041 cps and 20476 cps at an activity of 3.5 MBq. Addition of extra axial detection planes to the half-ring configuration provided increases in system sensitivity by a factor of approximately 10. Conclusions: Initial simulations demonstrated that the configuration of a single half-ring 8 detector of monolithic BGO crystals could describe the a simulated BTAC in a clinically relevant forearm phantom with good signal properties, and an increased number of axial detection planes can provide increased sensitivity of the system. The system would find use in the derivation of the BTAC for use in the application of kinetic models without physical arterial sampling or reliance on image-based techniques.

High detection efficiency neutron sensitive microchannel plate

2013 ◽  
Vol 8 (01) ◽  
pp. P01015-P01015 ◽  
Author(s):  
J Pan ◽  
Y Yang ◽  
Y Tian ◽  
M Zeng ◽  
T Deng ◽  
...  
Keyword(s):  
Detection Efficiency ◽  
Microchannel Plate ◽  
High Detection ◽  
High Detection Efficiency

scholarly journals First measurements with the new 3He-filled Monoblock Aluminium Multitube neutron detector developed at the ILL for ANSTO PLATYPUS reflectometer

2020 ◽  
pp. 1-15
Author(s):  
Luis Abuel ◽  
Friedl Bartsch ◽  
Andrew Berry ◽  
Jean-Claude Buffet ◽  
Sylvain Cuccaro ◽  
...  
Keyword(s):  
Research Collaboration ◽  
Detection Efficiency ◽  
Mechanical Design ◽  
Performance Parameters ◽  
Detector Performance ◽  
High Detection ◽  
Neutron Wavelength ◽  
High Detection Efficiency ◽  
Main Detector ◽  
Characterisation Methods

A detector upgrade was carried out on the PLATYPUS instrument dedicated to neutron reflectometry at the Australian Nuclear Science and Technology Organisation (ANSTO). The new detector, developed in the framework of a research collaboration between the ILL and ANSTO, is based on the Monoblock Aluminium Multi-tube (MAM) detector design already in use on several reflectometers and SANS instruments at the ILL. This article provides a technical description of the mechanical design and read-out electronics of the PLATYPUS detector and its commissioning on the PLATYPUS instrument. The main detector performance parameters have been measured and are presented here as well as the characterisation methods and the results of several reflectometry measurements. These measurements show an improvement in experimental data quality resulting from high positional resolution, high detection efficiency and reduced neutron scattering background in the 2.5–19 Å neutron wavelength range used in PLATYPUS instrument.

scholarly journals Potentialities of the future technical improvements in the search of rare nuclear decays by bolometers

2018 ◽  
Vol 33 (09) ◽  
pp. 1843003 ◽  
Author(s):  
Fabio Bellini
Keyword(s):  
Nuclear Physics ◽  
Detection Efficiency ◽  
Neutrinoless Double Beta Decay ◽  
Double Beta Decay ◽  
Particle Identification ◽  
X Ray ◽  
High Detection ◽  
High Detection Efficiency ◽  
Hybrid Devices ◽  
Excellent Energy Resolution

Bolometers are cryogenic calorimeters which feature excellent energy resolution, low energy threshold, high detection efficiency, flexibility in choice of materials, particle identification capability if operated as hybrid devices. After 30 years of rapid progresses, they represent nowadays a leading technology in several fields: particle and nuclear physics, X-ray astrophysics, cosmology. However, further and substantial developments are required to increase the sensitivity to the levels envisioned by future researches. A review of the challenges to be addressed and potentialities of bolometers in the search for rare nuclear decays is given, with particular emphasis to the neutrinoless double beta decay physics case.

Movements of mottled sculpins (Cottus bairdii) in a Michigan stream: how restricted are they?

2009 ◽  
Vol 66 (1) ◽  
pp. 31-41 ◽  
Author(s):  
Matthew J. Breen ◽  
Carl R. Ruetz ◽  
Kurt J. Thompson ◽  
Steven L. Kohler
Keyword(s):  
Home Range ◽  
Standard Error ◽  
Small Proportion ◽  
Detection Efficiency ◽  
Maximum Displacement ◽  
Passive Integrated Transponder ◽  
Seasonal Movement ◽  
High Detection ◽  
High Detection Efficiency ◽  
Movement Distance

We monitored 94 mottled sculpins ( Cottus bairdii ) marked with passive integrated transponder (PIT) tags to examine seasonal movement patterns. High detection efficiency (mean ± standard error = 0.76 ± 0.03) of PIT-tagged fish was obtained with a portable antenna. Nighttime searches were more effective than daytime relocations in summer, and smaller fish (<65 mm) were detected more readily than larger fish (≥65 mm). Sculpins used erosional habitats more than depositional habitats, particularly during summer and nighttime. Search attempts within a 150 m reach showed that displacement, mean movement distance, and home range did not differ significantly between summer and winter, suggesting that season did not strongly influence movement. Additionally, movement metrics were unrelated to sculpin size. However, supplementary searches of a larger reach (700 m) showed that 16% of PIT-tagged fish moved more than 100 m over 1 year, with a maximum displacement of 511 m, and mobile fish typically displayed upstream bias. Although most mottled sculpins in our system were relatively sedentary, a small proportion of individuals moved further than previously reported for other systems.

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