Are we overlooking the rural patient journey when it comes to sepsis diagnosis and management?

2021 ◽  
Author(s):  
Jordan Kirby
Keyword(s):  
Rural Patient ◽  
Patient Journey ◽  
Diagnosis And Management ◽  
Sepsis Diagnosis

Improving Recognition of Abnormal Vital Signs: A Key Area of Intervention for Earlier Sepsis Diagnosis and Management

2020 ◽  
Vol 21 (3) ◽  
pp. B22
Author(s):  
Zaib Khan ◽  
Zaib Khan ◽  
Shivani Chopra ◽  
Katerina Oikonomou ◽  
Daniel Gaballa ◽  
...  
Keyword(s):  
Vital Signs ◽  
Diagnosis And Management ◽  
Sepsis Diagnosis

scholarly journals Expert Perspectives on Hereditary Angioedema: Key Areas for Advancements in Care across the Patient Journey

2016 ◽  
Vol 7 (3) ◽  
pp. ar.2016.7.0165 ◽  
Author(s):  
Aleena Banerji ◽  
Murat Baş ◽  
Jonathan A. Bernstein ◽  
Isabelle Boccon-Gibod ◽  
Maria Bova ◽  
...  
Keyword(s):  
Health Care Providers ◽  
Hereditary Angioedema ◽  
Delayed Diagnosis ◽  
Scientific Data ◽  
Online Information ◽  
Care Providers ◽  
C1 Inhibitor Deficiency ◽  
Patient Journey ◽  
Diagnosis And Management ◽  
Awareness Campaigns

Background Published literature documents the substantial burden of hereditary angioedema (HAE) with C1 inhibitor deficiency on the quality of life and work productivity of patients. However, despite advances in the field and the availability of guidelines to advise health care providers (HCP) on the diagnosis and management of HAE, there are still many challenges to overcome. For example, delayed diagnosis and misdiagnosis are common, and treatment practices vary worldwide. Objective An international expert panel was convened to consider opportunities for improvements that would benefit patients with HAE. Methods Based on professional and personal experiences, the experts developed schematics to describe the journey of patients through the following stages: (1) onset of symptoms and initial evaluation; (2) referral/diagnosis; and (3) management of HAE. More importantly, the panel identified key areas in which it was possible to optimize the support provided to patients and HCPs along this journey. Results Overall, this approach highlighted the need for wider dissemination of algorithms and scientific data to more effectively educate HCPs from multiple disciplines and the need for more research to inform appropriate treatment decisions. Furthermore, HAE awareness campaigns, accurate online information, and referral to patient advocacy groups were all considered helpful approaches to support patients. Conclusion More detailed and widespread information on the diagnosis and management of HAE is needed and may lead to advancements in care throughout the journey of the patient with HAE.

scholarly journals How Can the Microbiologist Help in Diagnosing Neonatal Sepsis?

2012 ◽  
Vol 2012 ◽  
pp. 1-14 ◽  
Author(s):  
Michela Paolucci ◽  
Maria Paola Landini ◽  
Vittorio Sambri
Keyword(s):  
Blood Culture ◽  
Neonatal Sepsis ◽  
Gold Standard ◽  
Early Onset ◽  
Late Onset ◽  
Molecular Techniques ◽  
Diagnosis And Treatment ◽  
Diagnosis And Management ◽  
Sepsis Diagnosis ◽  
Expected Outcomes

Neonatal sepsis can be classified into two subtypes depending upon whether the onset of symptoms is before 72 hours of life (early-onset neonatal sepsis—EONS) or later (late-onset neonatal sepsis—LONS). These definitions have contributed greatly to diagnosis and treatment by identifying which microorganisms are likely to be responsible for sepsis during these periods and the expected outcomes of infection. This paper focuses on the tools that microbiologist can offer to diagnose and eventually prevent neonatal sepsis. Here, we discuss the advantages and limitation of the blood culture, the actual gold standard for sepsis diagnosis. In addition, we examine the utility of molecular techniques in the diagnosis and management of neonatal sepsis.

scholarly journals Delays to Diagnosis and Management of Upper Tract Urothelial Carcinoma

2019 ◽  
Vol 2 (3) ◽  
pp. e5-e11
Author(s):  
William S Taylor
Keyword(s):  
Urothelial Carcinoma ◽  
Renal Cancer ◽  
Incidental Finding ◽  
Day Treatment ◽  
Waiting Times ◽  
Upper Tract Urothelial Carcinoma ◽  
Patient Journey ◽  
Upper Tract ◽  
Diagnosis And Management ◽  
Carcinoma Of The Bladder

Background and Objective Upper tract urothelial carcinoma (UTUC) is rare in comparison to urothelial carcinoma of the bladder or renal cell carcinoma. UTUC may present with loin pain, haematuria or alternatively can be identified as an incidental finding on imaging. There are often delays to diagnosis as haematuria clinics are efficient for bladder and renal cancer but less effective for UTUC. The diagnosis and treatment of UTUC is more challenging, as it often requires two operations and multiple MDT discussions. Diagnosis must be certain to avoid unnecessary radical surgery.   We found that our patients were experiencing significant delays to definitive surgery. Our patients currently follow the pathway for bladder and renal cancer, as there is no UTUC pathway at or trust or published in the literature.  We audited our diagnostic pathway to see how we could tailor the pathway to be more effective for patients with UTUC. This will ensure that more patients will meet the NHS 62-day targets.   Materials and Methods A retrospective review of patients management pathway from December 2008 to December 2018. Patients were identified by the pathological code for UTUC.   Results A total of 62 patients underwent nephroureterectomy during a 10-year period. 48 patients were analysed. The median waiting time for haematuria clinic from referral was 21days, a further 73 days to ureterorenoscopy and biopsy, and then 14 days to definitive nephroureterectomy. Only one patient met the NHS 62-day treatment target.   Our waiting times are comparable with other published international series. We have implemented a new UTUC pathway to streamline the diagnosis and management of UTUC. Some patients with UTUC will still have inevitable delays as diagnosis can be very challenging but this new pathway should improve the patient journey and reduce the waiting times significantly.

scholarly journals Knowledge assessment of Sepsis Diagnosis and Management during COVID-19 pandemic among House Officers & Medical Officers in Ibrahim Malik Teaching Hospital in Khartoum State, Sudan, 2021

2021 ◽  
Author(s):  
ElMuiz Abdelrahman ◽  
Khabab Abbasher Hussien Mohamed Ahmed ◽  
Ibrahim Mahgoub ◽  
Mohammed Eltahier Abdalla Omer ◽  
Yassin Abdelrahim Abdalla ◽  
...  
Keyword(s):  
Medical Knowledge ◽  
Knowledge Score ◽  
P Value ◽  
Sepsis Management ◽  
Cross Sectional ◽  
Diagnosis And Management ◽  
Sepsis Diagnosis ◽  
Significant Difference ◽  
Life Threatening ◽  
The Mean

Abstract Background: Sepsis is life-threatening and frequently a final common pathway to death for many infectious diseases worldwide and may lead to death if left untreated. The objective is to assess the scientific medical knowledge upon sepsis among House officers and Medical officers in terms of diagnosis and management.Method: An observational cross sectional Hospital-based study was conducted through self-administered retrospective questionnaires based on the objective of the study. We enrolled 155 participants through Convenience sampling. The questionnaire contains parts of validated Sepsis criteria in terms of diagnosis and management. Analysis was done by using SPSS version 20. Data are presenter as frequencies and percentages using figures and tables. P value less than 0.05 considered significant Mann Whitney U test use to compare level of knowledge adherence between trained participants and non-trained participants.Results: The mean knowledge score about sepsis diagnosis was 2.6 out of 10 (SD= 1.8), and about sepsis management was 2.8 out of 8 (SD=1.8) the mean overall score was 5.5 out of 18.No significant difference found between participants who were trained upon diagnosis and management of sepsis and those who were not.Conclusion: Study findings illustrated that the capacity to perceive and manage sepsis among House Officers and Medical Officers doctors is poor and there are dangerous gaps in their investigation and management of such septic patients.

scholarly journals Advances in sepsis diagnosis and management: a paradigm shift towards nanotechnology

2021 ◽  
Vol 28 (1) ◽  
Author(s):  
Amit Pant ◽  
Irene Mackraj ◽  
Thirumala Govender
Keyword(s):  
Critical Role ◽  
Sepsis Management ◽  
Diagnosis And Management ◽  
Resistance Surface ◽  
Sepsis Diagnosis ◽  
Reactive Protein ◽  
Extracorporeal Blood Purification ◽  
Highly Sensitive ◽  
Life Threatening

AbstractSepsis, a dysregulated immune response due to life-threatening organ dysfunction, caused by drug-resistant pathogens, is a major global health threat contributing to high disease burden. Clinical outcomes in sepsis depend on timely diagnosis and appropriate early therapeutic intervention. There is a growing interest in the evaluation of nanotechnology-based solutions for sepsis management due to the inherent and unique properties of these nano-sized systems. This review presents recent advancements in nanotechnology-based solutions for sepsis diagnosis and management. Development of nanosensors based on electrochemical, immunological or magnetic principals provide highly sensitive, selective and rapid detection of sepsis biomarkers such as procalcitonin and C-reactive protein and are reviewed extensively. Nanoparticle-based drug delivery of antibiotics in sepsis models have shown promising results in combating drug resistance. Surface functionalization with antimicrobial peptides further enhances efficacy by targeting pathogens or specific microenvironments. Various strategies in nanoformulations have demonstrated the ability to deliver antibiotics and anti-inflammatory agents, simultaneously, have been reviewed. The critical role of nanoformulations of other adjuvant therapies including antioxidant, antitoxins and extracorporeal blood purification in sepsis management are also highlighted. Nanodiagnostics and nanotherapeutics in sepsis have enormous potential and provide new perspectives in sepsis management, supported by promising future biomedical applications included in the review.

Role of the allergist in diagnosis and management of patients with uveitis

JAMA ◽  
1966 ◽  
Vol 195 (3) ◽  
pp. 167-172 ◽  
Author(s):  
T. E. Van Metre
Keyword(s):  
Diagnosis And Management
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