The burden of ischemic heart disease and type 2 diabetes mellitus attributable to diet high in sugar‐sweetened beverages in China: An analysis for the Global Burden of Disease Study 2017

2020 ◽  
Author(s):  
Man Li ◽  
Xiaojie Li ◽  
Yanfang Zhao ◽  
Lu Zhang ◽  
Jing Yang ◽  
...  
2021 ◽  
Vol 12 ◽  
Author(s):  
Ying Wu ◽  
Rongguo Fu ◽  
Chen Lei ◽  
Yujiao Deng ◽  
Weiyang Lou ◽  
...  

BackgroundEpidemiological trends of type 2 diabetes mellitus attributable to fine particulate matter (PM2.5) pollution remain unclear. Here, we estimated spatiotemporal trends of type 2 diabetes mellitus burden attributable to PM2.5 pollution, including ambient particulate matter pollution (APMP) and household air pollution (HAP), from 1990–2019.MethodsData were obtained from the Global Burden of Disease Study 2019 and were analyzed by age, sex, year, and location. Joinpoint regression analysis was applied in the analysis of temporal trends in type 2 diabetes mellitus burden over the 30 years.ResultsGlobally, PM2.5 pollution contributed to 292.5 thousand deaths and 13 million disability-adjusted life-years (DALYs) in 2019. APMP ranked third among all risk factors, causing an increase in type 2 diabetes mellitus burden from 1990, whereas the impact of HAP significantly fell during the same period. Both APMP and HAP contributed the most to deaths and DALYs of type 2 diabetes mellitus among older people. However, the age-standardized death and DALY rates of type 2 diabetes mellitus attributable to APMP were greater among males and people in the middle socio-demographic index countries, especially in Southern Sub-Saharan Africa. For HAP, type 2 diabetes mellitus burden was modestly higher in females and was highest in Oceania, which was the only region with an increase from 1990.ConclusionsPM2.5 pollution resulted in substantial and increasing type 2 diabetes mellitus burden worldwide. Hence, governments and health systems should take steps to reduce air pollution to mitigate this increasing burden.


PLoS ONE ◽  
2021 ◽  
Vol 16 (2) ◽  
pp. e0246635
Author(s):  
Juyoung Kim ◽  
Seok-Jun Yoon ◽  
Min-Woo Jo

Background The burden of diabetes is considerable not only globally but also nationally within Korea. The Global Burden of Disease study derived the disability-adjusted life years (DALYs) of diabetes depending on its complications as individual severity using prevalence-based approach from 2017. Conversely, the Korean National Burden of Disease study based on an incidence-based approach does not incorporate the severity of diseases. This study aimed to simulate incidence-based DALYs of type 2 diabetes mellitus (T2DM), given diabetic complications as disease severity using a Markov model. Methods We developed a model with six Markov states, including incident and existing prevalent cases of diabetes and its complications and death. We assumed that diabetes and its complications would not be cured. The cycle length was one year, and the endpoint of the simulation was 100 years. A 5% discount rate was adopted in the analysis. Transition cases were counted by 5-year age groups above 30 years of age. Age- and sex-specific transition probabilities were calculated based on the incident rate. Results The total DALY estimates of T2DM were 5,417 and 3,934 per 100,000 population in men and women, respectively. The years of life lost in men were relatively higher than those in women in most age groups except the 80–84 age group. The distribution of years lived with disability by gender and age group showed a bell shape, peaking in the 55–59 age group in men and 65–69 age group in women. Conclusions The burden of T2DM considering its complications was larger compared to the outcomes from previous studies, with more precise morbid duration using the Markov model.


2012 ◽  
Vol 15 (1) ◽  
pp. 19-24
Author(s):  
Natalya Ivanovna Volkova ◽  
Andrey Vladimirovich Kharakhashyan ◽  
Yulia Alekseevna Sorokina ◽  
Il'ya Yur'evich Davidenko

Aims. Development of assessment model for type 2 diabetes mellitus (DM) patient stratification for painless ischemic heart disease(IHD). Materials and methods. 258 patients with DM type 2 participated in this study (109 male and 149 female) of mean age 58.4?8.5 withDM experience of 7.9?6.1 years. All participants were subdivided into three groups: first - DM type 2 without history of painless IHD(138 individuals); second - DM type 2 with diagnosed painless IHD (50 individuals); third - DM type 2 with painful myocardialischemia. We assessed "classic" risk factors for IHD, immediately connected with DM comorbidity, as well as "additional" risk factors,potentially capable of provoking both painless and painful IHD. In addition, we screened our patients for structural abnormalitiesof heart by means of echocardiography. Painless IHD was diagnosed by treadmill-tests or Holter monitoring with submaximal exercise.Accumulated data was statistically processed with the use of Spearman's rank correlation, as well as binary logistic regression method.Results were deemed statistically significant at р


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