Multivariate classification of earthquake survivors with post‐traumatic stress disorder based on large‐scale brain networks

2020 ◽  
Vol 141 (3) ◽  
pp. 285-298 ◽  
Author(s):  
H. Zhu ◽  
M. Yuan ◽  
C. Qiu ◽  
Z. Ren ◽  
Y. Li ◽  
...  
Keyword(s):  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Large Scale ◽  
Stress Disorder ◽  
Brain Networks ◽  
Post Traumatic Stress ◽  
Multivariate Classification ◽  
Post Traumatic ◽  
Earthquake Survivors

The Association between COMT Val158Met Polymorphism and the Post-Traumatic Stress Disorder Risk: A Meta-Analysis

2021 ◽  
pp. 1-14
Author(s):  
Mi Su ◽  
Yongyan Song
Keyword(s):  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Large Scale ◽  
Stress Disorder ◽  
Meta Analysis ◽  
Cochrane Library ◽  
Post Traumatic Stress ◽  
Val158met Polymorphism ◽  
Post Traumatic ◽  
The Impact

<b><i>Background:</i></b> Genetic factors were suggested to have influence on the development of post-traumatic stress disorder (PTSD). The possible association between catechol-O-methyltransferase (<i>COMT</i>) Val158Met polymorphism and PTSD has been evaluated in several studies. But the results were still controversial. Therefore, we conduct this meta-analysis to address these issues. <b><i>Methods:</i></b> The PubMed, EMBASE, Cochrane Library, and Web of Science databases were searched for eligible studies. The pooled odds ratio (OR) with 95% confidence interval (CI) was calculated to estimate the association between <i>COMT</i> Val158Met polymorphism and PTSD. <b><i>Results:</i></b> Five articles including 6 studies with 893 cases and 968 controls were finally included in the present meta-analysis. The pooled analyses did not demonstrate a significant association between the <i>COMT</i> Val158Met polymorphism and PTSD in any of the selected genetic models: allele model (OR = 1.13, 95% CI: 0.97–1.31), dominant model (OR = 1.17, 95% CI: 0.93–1.46), recessive model (OR = 1.44, 95% CI: 0.78–2.66), and additive model (OR = 1.54, 95% CI: 0.85–2.80). Subgroup analyses suggested that the Hardy-Weinberg equilibrium status of genotype distributions could influence the relationship of <i>COMT</i> Val158Met polymorphism and PTSD. <b><i>Conclusions:</i></b> The present meta-analysis suggested that the <i>COMT</i> Val158Met polymorphism may not be associated with the PTSD risk. Further large-scale and population-representative studies are warranted to evaluate the impact of the <i>COMT</i> Val158Met polymorphism on the risk of PTSD.

scholarly journals ‘Military Munchausen's’: assessment of factitious claims of military service in psychiatric patients

1998 ◽  
Vol 22 (3) ◽  
pp. 153-154 ◽  
Author(s):  
Martin Baggaley
Keyword(s):  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Military Service ◽  
Stress Disorder ◽  
Psychiatric Patients ◽  
Post Traumatic Stress ◽  
Military Experience ◽  
Simple Classification ◽  
Post Traumatic

Thirteen per cent of referrals of ex-servicemen to a military psychiatric centre for the treatment of combat-related post-traumatic stress disorder (PTSD) in a 12-month period have proved to be factitious. A simple classification of factitious combat-related PTSD into those with no military service and those with military service but with false claims of combat is described. The possible causes of this behaviour are discussed and a guide to the detection of factitious claims for psychiatrists without military experience is given.

Serum total oxidant and antioxidant status in earthquake survivors with post-traumatic stress disorder

2015 ◽  
Vol 27 (3) ◽  
pp. 153-158 ◽  
Author(s):  
Pinar Guzel Ozdemir ◽  
İbrahim Kaplan ◽  
Cem Uysal ◽  
Mahmut Bulut ◽  
Abdullah Atli ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Antioxidant Status ◽  
Stress Disorder ◽  
Total Antioxidant Status ◽  
Post Traumatic Stress ◽  
Total Antioxidant ◽  
Post Traumatic ◽  
Earthquake Survivors

ObjectiveOxidative stress has been shown to play an important role in the pathogenesis of post-traumatic stress disorder (PTSD). Although there are some studies on oxidative stress and PTSD, there is no report available on the serum total oxidant and antioxidant status in earthquake survivors with PTSD. Therefore, this study aimed to investigate the serum total oxidant and antioxidant status in earthquake survivors with chronic PTSD.Material and MethodsThe study group included 45 earthquake survivors with PTSD and 40 earthquake survivors without PTSD. The oxidative status was determined using the total antioxidant status and total oxidant status (TOS) measurements and by calculating the oxidative stress index (OSI).ResultsThere were no statistically significant differences in the total antioxidant status, TOS, or OSI when comparing individuals with and without PTSD (all,p>0.05). There were no correlations between Clinician-Administered PTSD Scale scores and oxidant and antioxidant stress markers (all,p>0.05).ConclusionsOur results suggest that the total oxidant and antioxidant status may not affect earthquake survivors with PTSD. This is the first study to evaluate the oxidative status in earthquake survivors with PTSD. Further studies are necessary to confirm these findings.

Plasma brain-derived neurotrophic factor in earthquake survivors with full and partial post-traumatic stress disorder

2013 ◽  
Vol 67 (5) ◽  
pp. 363-364 ◽  
Author(s):  
Paolo Stratta ◽  
Roberto L. Bonanni ◽  
Patrizia Sanità ◽  
Stefano de Cataldo ◽  
Adriano Angelucci ◽  
...  
Keyword(s):  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Neurotrophic Factor ◽  
Stress Disorder ◽  
Brain Derived Neurotrophic Factor ◽  
Post Traumatic Stress ◽  
Post Traumatic ◽  
Earthquake Survivors

scholarly journals Post-traumatic stress disorder and resilience among flood affected farmers of Kerala, India

2021 ◽  
Vol 8 (4) ◽  
pp. 1842
Author(s):  
Manu Jose ◽  
Jessy Fenn
Keyword(s):  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Large Scale ◽  
Stress Disorder ◽  
Significant Negative Correlation ◽  
Post Traumatic Stress ◽  
Resilience Scale ◽  
Post Traumatic ◽  
Extreme Flooding ◽  
The Relationship

Background: In mid-August 2018, Kerala witnessed the worst floods since 1924 due to abnormally high rainfall and simultaneous release of water from its dams, resulting in extreme flooding in 13 of the 14 districts in the State. The large-scale flooding impacted millions of people and caused nearly 400 deaths as well as immense damage to property. This was followed by flooding yet again in August 2019, thereby triggering further damage. Farmers whose crops got completely wiped out were one group that were severely affected. This study investigated the presence of post-traumatic stress disorder (PTSD) in farmers and also checked the relationship between PTSD and resilience. Methods: The sample consisted of 100 farmers from the Alappuzha and Pattanamtitta districts of Kerala which were severely affected by the flood. Data was collected through the PTSD-8, Brief Resilience Scale (BRS) along with sociodemographic data and flood related information.Results: 74% of the farmers scored high on the test indicating the presence of PTSD. The farmers of interior Pathanamthitta had significantly higher incidence (84%) of PTSD than coastal Alappuzha farmers (66%). The level of damage due to the flood did not have significant correlation with PTSD.  There was significant negative correlation between PTSD and resilience (r=-0.64).Conclusions: There was high incidence of PTSD among the farmers of central Kerala post the 2018 and 2019 floods and it was higher in interior Pathanamthitta than in coastal Alappuzha which is more used to the vagaries of the waters. Resilience helps to combat PTSD. 

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