scholarly journals Enhanced local and systemic inflammatory cytokine mRNA expression in women with endometriosis evokes compensatory adaptive regulatory mRNA response that mediates immune suppression and impairs cytotoxicity

2020 ◽  
Vol 84 (4) ◽  
Author(s):  
Emma Björk ◽  
Marie‐Therese Vinnars ◽  
Ivan Nagaev ◽  
Olga Nagaeva ◽  
Eva Lundin ◽  
...  
Keyword(s):  
Mrna Expression ◽  
Immune Suppression ◽  
Inflammatory Cytokine ◽  
Cytokine Mrna ◽  
Cytokine Mrna Expression

scholarly journals 88. Insemination induces pro-inflammatory cytokine mRNA expression in the human cervix

2003 ◽  
Vol 15 (9) ◽  
pp. 88 ◽  
Author(s):  
David J. Sharkey ◽  
Melinda J. Jasper ◽  
Kelton P. Tremellen ◽  
Kristina Gemzell-Danielsson ◽  
Sarah A. Robertson
Keyword(s):  
Mrna Expression ◽  
Inflammatory Cytokine ◽  
Cytokine Mrna ◽  
Cytokine Mrna Expression ◽  
Human Cervix

scholarly journals Heterophils isolated from chickens resistant to extra-intestinal Salmonella enteritidis infection express higher levels of pro-inflammatory cytokine mRNA following infection than heterophils from susceptible chickens

2004 ◽  
Vol 132 (6) ◽  
pp. 1029-1037 ◽  
Author(s):  
PAMELA J. FERRO ◽  
CHRISTINA L. SWAGGERTY ◽  
PETE KAISER ◽  
IGAL Y. PEVZNER ◽  
MICHAEL H. KOGUT
Keyword(s):  
Mrna Expression ◽  
Real Time ◽  
Salmonella Enteritidis ◽  
Inflammatory Cytokine ◽  
Rt Pcr ◽  
Cytokine Mrna ◽  
Reciprocal Crosses ◽  
First Report ◽  
Cytokine Mrna Expression

Previous studies showed differences in in vitro heterophil function between parental (A>B) broilers and F1 reciprocal crosses (D>C). Our objectives were to (1) determine if in vitro variations translate to differences in resistance to Salmonella enteritidis (SE) and (2) quantitate cytokine mRNA in heterophils from SE-infected chicks. One-day-old chicks were challenged and organs were cultured for SE. Chicks with efficient heterophils (A and D) were less susceptible to SE compared to chicks with inefficient heterophils (B and C). Heterophils were isolated from SE-infected chicks and cytokine mRNA expression was evaluated using quantitative real-time RT–PCR. Pro-inflammatory cytokine mRNA was up-regulated in heterophils from SE-resistant chicks compared to susceptible chicks. This is the first report to quantitate cytokine mRNA in heterophils from SE-infected chicks. These data show a relationship between in vitro heterophil function, increased pro-inflammatory cytokine mRNA expression, and increased resistance to SE in 1-day-old chicks.

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