Review article: alcohol and gut microbiota - the possible role of gut microbiota modulation in the treatment of alcoholic liver disease

2015 ◽  
Vol 41 (10) ◽  
pp. 917-927 ◽  
Author(s):  
G. Vassallo ◽  
A. Mirijello ◽  
A. Ferrulli ◽  
M. Antonelli ◽  
R. Landolfi ◽  
...  
2020 ◽  
Vol 26 (4) ◽  
pp. 633-638
Author(s):  
Reiichiro Kondo ◽  
Yasuko Iwakiri

The lymphatic system plays vital roles in interstitial fluid balance and immune cell surveillance. The effect of alcohol on the lymphatic system is poorly understood. This review article explores the role of the lymphatic system in the pathogenesis of alcohol-related disease including alcoholic liver disease (ALD) and the therapeutic potential of targeting hepatic lymphatics for the treatment of ALD.


2019 ◽  
Vol 141 ◽  
pp. 521-529 ◽  
Author(s):  
Yufang Ding ◽  
Karin Yanagi ◽  
Clint Cheng ◽  
Robert C. Alaniz ◽  
Kyongbum Lee ◽  
...  

2016 ◽  
Vol 11 (3) ◽  
pp. 213-219 ◽  
Author(s):  
Emidio Scarpellini ◽  
Forlino Mariana ◽  
Lupo Marinella ◽  
Rasetti Carlo ◽  
Fava Giammarco ◽  
...  

2020 ◽  
Vol 10 (4) ◽  
Author(s):  
Sha Li ◽  
Ning Wang ◽  
Hor‐Yue Tan ◽  
Fan Chueng ◽  
Zhang‐Jin Zhang ◽  
...  

2021 ◽  
Author(s):  
Mei Ji ◽  
Cheng Fang ◽  
Wei Jia ◽  
Hai Du ◽  
Yan Xu

Ethanol (EtOH) is the main risk factor for alcoholic liver disease. However, fermented alcoholic beverages contain not only ethanol but also various volatile compounds. Currently, effects of volatile compounds in...


2020 ◽  
Vol 22 (1) ◽  
pp. 199
Author(s):  
Na Young Lee ◽  
Ki Tae Suk

Liver cirrhosis is one of the most prevalent chronic liver diseases worldwide. In addition to viral hepatitis, diseases such as steatohepatitis, autoimmune hepatitis, sclerosing cholangitis and Wilson’s disease can also lead to cirrhosis. Moreover, alcohol can cause cirrhosis on its own and exacerbate chronic liver disease of other causes. The treatment of cirrhosis can be divided into addressing the cause of cirrhosis and reversing liver fibrosis. To this date, there is still no clear consensus on the treatment of cirrhosis. Recently, there has been a lot of interest in potential treatments that modulate the gut microbiota and gut-liver axis for the treatment of cirrhosis. According to recent studies, modulation of the gut microbiome by probiotics ameliorates the progression of liver disease. The precise mechanism for relieving cirrhosis via gut microbial modulation has not been identified. This paper summarizes the role and effects of the gut microbiome in cirrhosis based on experimental and clinical studies on absorbable antibiotics, probiotics, prebiotics, and synbiotics. Moreover, it provides evidence of a relationship between the gut microbiome and liver fibrosis.


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