scholarly journals Alcohol Induced Gut Microbiota Modulation: The Role of Probiotics, Pufas, and Vitamin E in Management of Alcoholic Liver Disease

2021 ◽  
Vol 05 (13) ◽  
Author(s):  
Faruqui AA
2019 ◽  
Vol 141 ◽  
pp. 521-529 ◽  
Author(s):  
Yufang Ding ◽  
Karin Yanagi ◽  
Clint Cheng ◽  
Robert C. Alaniz ◽  
Kyongbum Lee ◽  
...  

2015 ◽  
Vol 41 (10) ◽  
pp. 917-927 ◽  
Author(s):  
G. Vassallo ◽  
A. Mirijello ◽  
A. Ferrulli ◽  
M. Antonelli ◽  
R. Landolfi ◽  
...  

2016 ◽  
Vol 11 (3) ◽  
pp. 213-219 ◽  
Author(s):  
Emidio Scarpellini ◽  
Forlino Mariana ◽  
Lupo Marinella ◽  
Rasetti Carlo ◽  
Fava Giammarco ◽  
...  

2020 ◽  
Vol 10 (4) ◽  
Author(s):  
Sha Li ◽  
Ning Wang ◽  
Hor‐Yue Tan ◽  
Fan Chueng ◽  
Zhang‐Jin Zhang ◽  
...  

2021 ◽  
Author(s):  
Mei Ji ◽  
Cheng Fang ◽  
Wei Jia ◽  
Hai Du ◽  
Yan Xu

Ethanol (EtOH) is the main risk factor for alcoholic liver disease. However, fermented alcoholic beverages contain not only ethanol but also various volatile compounds. Currently, effects of volatile compounds in...


2020 ◽  
Vol 22 (1) ◽  
pp. 199
Author(s):  
Na Young Lee ◽  
Ki Tae Suk

Liver cirrhosis is one of the most prevalent chronic liver diseases worldwide. In addition to viral hepatitis, diseases such as steatohepatitis, autoimmune hepatitis, sclerosing cholangitis and Wilson’s disease can also lead to cirrhosis. Moreover, alcohol can cause cirrhosis on its own and exacerbate chronic liver disease of other causes. The treatment of cirrhosis can be divided into addressing the cause of cirrhosis and reversing liver fibrosis. To this date, there is still no clear consensus on the treatment of cirrhosis. Recently, there has been a lot of interest in potential treatments that modulate the gut microbiota and gut-liver axis for the treatment of cirrhosis. According to recent studies, modulation of the gut microbiome by probiotics ameliorates the progression of liver disease. The precise mechanism for relieving cirrhosis via gut microbial modulation has not been identified. This paper summarizes the role and effects of the gut microbiome in cirrhosis based on experimental and clinical studies on absorbable antibiotics, probiotics, prebiotics, and synbiotics. Moreover, it provides evidence of a relationship between the gut microbiome and liver fibrosis.


2021 ◽  
Author(s):  
Giuseppe Ancona ◽  
Laura Alagna ◽  
Andrea Lombardi ◽  
Emanuele Palomba ◽  
Valeria Castelli ◽  
...  

Liver transplantation (LT) is a life-saving strategy for patients with end-stage liver disease, hepatocellular carcinoma and acute liver failure. LT success can be hampered by several short-term and long-term complications. Among them, bacterial infections, especially due to multidrug-resistant germs, are particularly frequent with a prevalence between 19 and 33% in the first 100 days after transplantation. In the last decades, a number of studies have highlighted how gut microbiota (GM) is involved in several essential functions to ensure the intestinal homeostasis, becoming one of the most important virtual metabolic organs. GM works through different axes with other organs, and the gut-liver axis is among the most relevant and investigated ones. Any alteration or disruption of GM is defined as dysbiosis. Peculiar phenotypes of GM dysbiosis have been associated to several liver conditions and complications, such as chronic hepatitis, fatty liver disease, cirrhosis and hepatocellular carcinoma. Moreover, there is growing evidence of the crucial role of GM in shaping the immune response, both locally and systemically, against pathogens. This paves the way to the manipulation of GM as a therapeutic instrument to modulate the infectious risk and outcome. In this minireview we provide an overview of the current understanding on the interplay between gut microbiota and the immune system in liver transplant recipients and the role of the former in infections.


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