The role of açaí ( Euterpe oleracea Mart. 1824) as a chemoprotective agent in the evaluation of antioxidant defence, oxidative damage and histology of juvenile shrimp Litopenaeus vannamei (BOONE, 1931) exposed to ammonia

2020 ◽  
Vol 51 (4) ◽  
pp. 1551-1566
Author(s):  
Grecica Mariana Colombo ◽  
Cleber dos Santos Simião ◽  
Marcos Josué Schmitz ◽  
Virgínia Fonseca Pedrosa ◽  
Luis Alberto Romano ◽  
...  

2020 ◽  
Vol 65 ◽  
pp. 103726 ◽  
Author(s):  
Matheus Henrique Romão ◽  
Graziele Freitas de Bem ◽  
Izabelle Barcellos Santos ◽  
Ricardo de Andrade Soares ◽  
Dayane Teixeira Ognibene ◽  
...  


2018 ◽  
Vol 19 (12) ◽  
pp. 4045 ◽  
Author(s):  
Martin Hönig ◽  
Lucie Plíhalová ◽  
Alexandra Husičková ◽  
Jaroslav Nisler ◽  
Karel Doležal

Cytokinins modulate a number of important developmental processes, including the last phase of leaf development, known as senescence, which is associated with chlorophyll breakdown, photosynthetic apparatus disintegration and oxidative damage. There is ample evidence that cytokinins can slow down all these senescence-accompanying changes. Here, we review relationships between the various mechanisms of action of these regulatory molecules. We highlight their connection to photosynthesis, the pivotal process that generates assimilates, however may also lead to oxidative damage. Thus, we also focus on cytokinin induction of protective responses against oxidative damage. Activation of antioxidative enzymes in senescing tissues is described as well as changes in the levels of naturally occurring antioxidative compounds, such as phenolic acids and flavonoids, in plant explants. The main goal of this review is to show how the biological activities of cytokinins may be related to their chemical structure. New links between molecular aspects of natural cytokinins and their synthetic derivatives with antisenescent properties are described. Structural motifs in cytokinin molecules that may explain why these molecules play such a significant regulatory role are outlined.



2012 ◽  
Vol 385 (12) ◽  
pp. 1199-1209 ◽  
Author(s):  
Cristiane Aguiar da Costa ◽  
Paola Raquel Braz de Oliveira ◽  
Graziele Freitas de Bem ◽  
Lenize Costa Reis Marins de Cavalho ◽  
Dayane Teixeira Ognibene ◽  
...  


2014 ◽  
Vol 32 (2) ◽  
pp. 161-168 ◽  
Author(s):  
Ewa Sadowska-Krępa ◽  
Barbara Kłapcińska ◽  
Tomasz Podgórski ◽  
Bartłomiej Szade ◽  
Katarzyna Tyl ◽  
...  


2017 ◽  
Vol 57 (2) ◽  
pp. 817-832 ◽  
Author(s):  
Viviane da Silva Cristino Cordeiro ◽  
Graziele Freitas de Bem ◽  
Cristiane Aguiar da Costa ◽  
Izabelle Barcellos Santos ◽  
Lenize Costa Reis Marins de Carvalho ◽  
...  






2020 ◽  
Vol 21 (5) ◽  
pp. 477-498
Author(s):  
Yongfeng Chen ◽  
Xingjing Luo ◽  
Zhenyou Zou ◽  
Yong Liang

Reactive oxygen species (ROS), an important molecule inducing oxidative stress in organisms, play a key role in tumorigenesis, tumor progression and recurrence. Recent findings on ROS have shown that ROS can be used to treat cancer as they accelerate the death of tumor cells. At present, pro-oxidant drugs that are intended to increase ROS levels of the tumor cells have been widely used in the clinic. However, ROS are a double-edged sword in the treatment of tumors. High levels of ROS induce not only the death of tumor cells but also oxidative damage to normal cells, especially bone marrow hemopoietic cells, which leads to bone marrow suppression and (or) other side effects, weak efficacy of tumor treatment and even threatening patients’ life. How to enhance the killing effect of ROS on tumor cells while avoiding oxidative damage to the normal cells has become an urgent issue. This study is a review of the latest progress in the role of ROS-mediated programmed death in tumor treatment and prevention and treatment of oxidative damage in bone marrow induced by ROS.



2014 ◽  
Vol 4 (3) ◽  
pp. 224-228
Author(s):  
Elaine Lima ◽  
Edna Santos ◽  
Robert Smith ◽  
Armando Sabaa-Srur


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