Effects of dietary pyridoxine on the skin immunity, tight junctions, antioxidants and apoptosis of grass carp ( Ctenopharyngodon idella ) infected with Aeromonas hydrophila

2021 ◽  
Author(s):  
Xin Zheng ◽  
Wei‐Dan Jiang ◽  
Lin Feng ◽  
Pei Wu ◽  
Yang Liu ◽  
...  
Keyword(s):  
Tight Junctions ◽  
Aeromonas Hydrophila ◽  
Grass Carp ◽  
Ctenopharyngodon Idella ◽  
Skin Immunity ◽  
Grass Carp Ctenopharyngodon Idella

scholarly journals Caffeine supplementation in diet mitigates Aeromonas hydrophila-induced impairment of the gill phosphotransfer network in grass carp Ctenopharyngodon idella

2019 ◽  
Vol 136 ◽  
pp. 103710 ◽  
Author(s):  
Matheus D. Baldissera ◽  
Carine de Freitas Souza ◽  
Juliane B. Dias ◽  
Aleksandro S. Da Silva ◽  
Bernardo Baldisserotto
Keyword(s):  
Aeromonas Hydrophila ◽  
Grass Carp ◽  
Ctenopharyngodon Idella ◽  
Grass Carp Ctenopharyngodon Idella

scholarly journals Effects of Dietary Zearalenone on Oxidative Stress, Cell Apoptosis, and Tight Junction in the Intestine of Juvenile Grass Carp (Ctenopharyngodon idella)

Toxins ◽  
2019 ◽  
Vol 11 (6) ◽  
pp. 333 ◽  
Author(s):  
Ya-Li Wang ◽  
Xiao-Qiu Zhou ◽  
Wei-Dan Jiang ◽  
Pei Wu ◽  
Yang Liu ◽  
...  
Keyword(s):  
Tight Junctions ◽  
Grass Carp ◽  
Structural Integrity ◽  
Ctenopharyngodon Idella ◽  
Related Factor ◽  
Distal Intestine ◽  
Fish Intestine ◽  
Mitogen Activated Protein ◽  
Grass Carp Ctenopharyngodon Idella ◽  
Proximal Intestine

Zearalenone (ZEA) is a prevalent mycotoxin with high toxicity in animals. In order to study its effect on juvenile grass carp (Ctenopharyngodon idella), six diets supplemented with different levels of ZEA (0, 535, 1041, 1548, 2002, and 2507 μg/kg diet) for 10 weeks were studied to assess its toxicity on intestinal structural integrity and potential mechanisms of action. Our report firstly proved that ZEA led to growth retardation and body deformity, and impaired the intestinal structural integrity of juvenile grass carp, as revealed by the following findings: (1) ZEA accumulated in the intestine and caused histopathological lesions; (2) ZEA resulted in oxidative injury, apoptosis, and breached tight junctions in the fish intestine, which were probably associated with Nuclear factor-erythroid 2-related factor 2 (Nrf2), p38 mitogen activated protein kinases (p38MAPK), and myosin light chain kinase (MLCK) signaling pathways, respectively. ZEA had no influence on the antioxidant gene levels of Kelch-like ECH associating protein 1 (Keap1)b (rather than Keap1a), glutathione-S-transferase (GST)P1, GSTP2 (not in the distal intestine (DI)), tight junctions occludin, claudin-c (not in the proximal intestine (PI)), or claudin-3c (not in the mid intestine (MI) or DI).

Bactericidal activity of grass carp Ctenopharyngodon idella C9-deficient serum against Aeromonas hydrophila

2011 ◽  
Vol 79 (7) ◽  
pp. 2083-2086 ◽  
Author(s):  
C. Ji ◽  
A. H. Li ◽  
J. Xie ◽  
D. F. Zhang ◽  
J. Y. Liu
Keyword(s):  
Bactericidal Activity ◽  
Aeromonas Hydrophila ◽  
Grass Carp ◽  
Ctenopharyngodon Idella ◽  
Grass Carp Ctenopharyngodon Idella

Molecular characterization of an interleukin-4/13B homolog in grass carp ( Ctenopharyngodon idella ) and its role in fish against Aeromonas hydrophila infection

2016 ◽  
Vol 57 ◽  
pp. 136-147 ◽  
Author(s):  
Zhi-Jing Yang ◽  
Chang-Hong Li ◽  
Jie Chen ◽  
Hao Zhang ◽  
Ming-Yun Li ◽  
...  
Keyword(s):  
Molecular Characterization ◽  
Aeromonas Hydrophila ◽  
Grass Carp ◽  
Ctenopharyngodon Idella ◽  
Interleukin 4 ◽  
Grass Carp Ctenopharyngodon Idella

scholarly journals Mannan Oligosaccharides Application: Multipath Restriction From Aeromonas hydrophila Infection in the Skin Barrier of Grass Carp (Ctenopharyngodon idella)

2021 ◽  
Vol 12 ◽  
Author(s):  
Zhiyuan Lu ◽  
Lin Feng ◽  
Wei-Dan Jiang ◽  
Pei Wu ◽  
Yang Liu ◽  
...  
Keyword(s):  
Signaling Pathway ◽  
Aeromonas Hydrophila ◽  
Grass Carp ◽  
Barrier Function ◽  
Pathogenic Bacteria ◽  
Skin Barrier ◽  
Ctenopharyngodon Idella ◽  
Skin Barrier Function ◽  
Grass Carp Ctenopharyngodon Idella ◽  
Mannan Oligosaccharides

The objective of this study was to evaluate the efficacy of dietary Mannan oligosaccharides (MOS) supplementation on skin barrier function and the mechanism of on-growing grass carp (Ctenopharyngodon idella). Five hundred forty grass carp were fed for 60 days from the growing stage with six different levels of MOS diets (0, 200, 400, 600, 800, and 1,000 mg kg-1). At the end of the growth trial, the 14-day Aeromonas hydrophila challenge experiment has proceeded. The obtained data indicate that MOS could (1) decline skin lesion morbidity after being challenged by the pathogenic bacteria; (2) maintain physical barrier function via improving antioxidant ability, inhibiting excessive apoptosis, and strengthening the tight junction between the epithelial cell and the related signaling pathway (Nrf2/Keap1, p38MAPK, and MLCK); and (3) regulate immune barrier function by modulating the production of antimicrobial compound and expression of involved cytokines and the related signaling pathway (TOR and NFκB). Finally, we concluded that MOS supplementation reinforced the disease resistance and protected the fish skin barrier function from Aeromonas hydrophila infection.

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