Machine learning algorithms for accurate differential diagnosis of lymphocytosis based on cell population data

BackgroundA wide variety of benign and malignant processes can manifest as non-mass enhancement (NME) in breast MRI. Compared to mass lesions, there are no distinct features that can be used for differential diagnosis. The purpose is to use the BI-RADS descriptors and models developed using radiomics and deep learning to distinguish benign from malignant NME lesions.Materials and MethodsA total of 150 patients with 104 malignant and 46 benign NME were analyzed. Three radiologists performed reading for morphological distribution and internal enhancement using the 5th BI-RADS lexicon. For each case, the 3D tumor mask was generated using Fuzzy-C-Means segmentation. Three DCE parametric maps related to wash-in, maximum, and wash-out were generated, and PyRadiomics was applied to extract features. The radiomics model was built using five machine learning algorithms. ResNet50 was implemented using three parametric maps as input. Approximately 70% of earlier cases were used for training, and 30% of later cases were held out for testing.ResultsThe diagnostic BI-RADS in the original MRI report showed that 104/104 malignant and 36/46 benign lesions had a BI-RADS score of 4A–5. For category reading, the kappa coefficient was 0.83 for morphological distribution (excellent) and 0.52 for internal enhancement (moderate). Segmental and Regional distribution were the most prominent for the malignant group, and focal distribution for the benign group. Eight radiomics features were selected by support vector machine (SVM). Among the five machine learning algorithms, SVM yielded the highest accuracy of 80.4% in training and 77.5% in testing datasets. ResNet50 had a better diagnostic performance, 91.5% in training and 83.3% in testing datasets.ConclusionDiagnosis of NME was challenging, and the BI-RADS scores and descriptors showed a substantial overlap. Radiomics and deep learning may provide a useful CAD tool to aid in diagnosis.

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Application of machine learning algorithms for the differential diagnosis of peroxisomal disorders

The Journal of Biochemistry ◽

10.1093/jb/mvy085 ◽

2018 ◽

Vol 165 (1) ◽

pp. 67-73 ◽

Cited By ~ 1

Author(s):

Pammi Subhashini ◽

Sampangi Jaya Krishna ◽

Ganni Usha Rani ◽

Nooguri Sushma Chander ◽

Gummadi Maheshwar Reddy ◽

...

Keyword(s):

Machine Learning ◽

Differential Diagnosis ◽

Learning Algorithms ◽

Machine Learning Algorithms ◽

Peroxisomal Disorders

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Classifier Model Based on Machine Learning Algorithms: Application to Differential Diagnosis of Suspicious Thyroid Nodules via Sonography

American Journal of Roentgenology ◽

10.2214/ajr.15.15813 ◽

2016 ◽

Vol 207 (4) ◽

pp. 859-864 ◽

Cited By ~ 22

Author(s):

Hongxun Wu ◽

Zhaohong Deng ◽

Bingjie Zhang ◽

Qianyun Liu ◽

Junyong Chen

Keyword(s):

Machine Learning ◽

Differential Diagnosis ◽

Thyroid Nodules ◽

Learning Algorithms ◽

Machine Learning Algorithms ◽

Model Based

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Supplemental Material for One Model to Rule Them All? Using Machine Learning Algorithms to Determine the Number of Factors in Exploratory Factor Analysis

Psychological Methods ◽

10.1037/met0000262.supp ◽

2020 ◽

Keyword(s):

Machine Learning ◽

Factor Analysis ◽

Exploratory Factor Analysis ◽

Learning Algorithms ◽

Machine Learning Algorithms ◽

Number Of Factors

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Forecasting US movies box office performances in Turkey using machine learning algorithms

Journal of Intelligent & Fuzzy Systems ◽

10.3233/jifs-189120 ◽

2020 ◽

Vol 39 (5) ◽

pp. 6579-6590

Author(s):

Sandy Çağlıyor ◽

Başar Öztayşi ◽

Selime Sezgin

Keyword(s):

Machine Learning ◽

Global Economy ◽

Learning Algorithms ◽

Forecast Model ◽

Machine Learning Algorithms ◽

Gradient Boosting ◽

High Stakes ◽

Box Office ◽

Industry Forecast ◽

The Impact

The motion picture industry is one of the largest industries worldwide and has significant importance in the global economy. Considering the high stakes and high risks in the industry, forecast models and decision support systems are gaining importance. Several attempts have been made to estimate the theatrical performance of a movie before or at the early stages of its release. Nevertheless, these models are mostly used for predicting domestic performances and the industry still struggles to predict box office performances in overseas markets. In this study, the aim is to design a forecast model using different machine learning algorithms to estimate the theatrical success of US movies in Turkey. From various sources, a dataset of 1559 movies is constructed. Firstly, independent variables are grouped as pre-release, distributor type, and international distribution based on their characteristic. The number of attendances is discretized into three classes. Four popular machine learning algorithms, artificial neural networks, decision tree regression and gradient boosting tree and random forest are employed, and the impact of each group is observed by compared by the performance models. Then the number of target classes is increased into five and eight and results are compared with the previously developed models in the literature.

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Intelligent system of English composition scoring model based on improved machine learning algorithm

Journal of Intelligent & Fuzzy Systems ◽

10.3233/jifs-189235 ◽

2020 ◽

pp. 1-11

Author(s):

Jie Liu ◽

Lin Lin ◽

Xiufang Liang

Keyword(s):

Machine Learning ◽

Evaluation System ◽

Intelligent System ◽

Learning Algorithm ◽

Learning Algorithms ◽

Machine Learning Algorithms ◽

Assessment System ◽

English Composition ◽

Region Extraction ◽

Constraint Model

The online English teaching system has certain requirements for the intelligent scoring system, and the most difficult stage of intelligent scoring in the English test is to score the English composition through the intelligent model. In order to improve the intelligence of English composition scoring, based on machine learning algorithms, this study combines intelligent image recognition technology to improve machine learning algorithms, and proposes an improved MSER-based character candidate region extraction algorithm and a convolutional neural network-based pseudo-character region filtering algorithm. In addition, in order to verify whether the algorithm model proposed in this paper meets the requirements of the group text, that is, to verify the feasibility of the algorithm, the performance of the model proposed in this study is analyzed through design experiments. Moreover, the basic conditions for composition scoring are input into the model as a constraint model. The research results show that the algorithm proposed in this paper has a certain practical effect, and it can be applied to the English assessment system and the online assessment system of the homework evaluation system algorithm system.

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The Unlearnable Checkerboard Pattern

Communications of the Blyth Institute ◽

10.33014/issn.2640-5652.1.2.holloway.1 ◽

2019 ◽

Vol 1 (2) ◽

pp. 78-80

Author(s):

Eric Holloway

Keyword(s):

Machine Learning ◽

Learning Algorithms ◽

Machine Learning Algorithms ◽

Checkerboard Pattern ◽

Simple Task

Detecting some patterns is a simple task for humans, but nearly impossible for current machine learning algorithms. Here, the "checkerboard" pattern is examined, where human prediction nears 100% and machine prediction drops significantly below 50%.

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