Intradermal testing for autoimmune progesterone dermatitis: should we be basing our diagnosis on it?

2021 ◽  
Author(s):  
H. Geros ◽  
D. Maor ◽  
C. Higgins ◽  
H.R. Bala ◽  
R. Nixon
Keyword(s):  
Intradermal Testing

7 Cases of Drug Eruptions, in which Generalized Rashes were Induced by Intradermal Testing.

1991 ◽  
Vol 53 (4) ◽  
pp. 705-712
Author(s):  
Sumi SAITO ◽  
Zenro IKEZAWA ◽  
Junko OSAWA ◽  
Shizuo NAITO ◽  
Michiko AIHARA ◽  
...  
Keyword(s):  
Intradermal Testing ◽  
Drug Eruptions

Patch testing and aeroallergen intradermal testing in facial dermatitis

2000 ◽  
Vol 43 (2) ◽  
pp. 90-94 ◽  
Author(s):  
Lin-Feng Li ◽  
Jing Wang
Keyword(s):  
Patch Testing ◽  
Intradermal Testing ◽  
Facial Dermatitis

History of chemical sensitivity and diagnosis

2016 ◽  
Vol 31 (3) ◽  
Author(s):  
William J. Rea
Keyword(s):  
Natural Gas ◽  
Polluted Water ◽  
Controlled Environment ◽  
Chemical Sensitivity ◽  
Intradermal Testing ◽  
Prosthetic Implants ◽  
Metal Plates ◽  
History Of ◽  
Total Body ◽  
Exhaust Jet

AbstractHistories of mold, pollen, dust, food, chemicals, and electromagnetic field (EMF) sensitivities are the major categories of triggers for chemical sensitivity. They are tied together by the coherence phenomenon, where each has its own frequencies and identifiable EMF; therefore, they can be correlated. The diagnosis of chemical sensitivity can be done accurately in a less-polluted, controlled environment, as was done in these studies. The principles of diagnosis and treatment depend on total environmental and total body pollutant loads, masking or adaptation, bipolarity of response, and biochemical individuality, among others. These principles make less-polluted, controlled conditions necessary. The clinician has to use less-polluted water and organic food with individual challenges for testing, including dust, mold, pesticide, natural gas, formaldehyde, particulates, and EMF testing, which needs to be performed in less-polluted copper-screened rooms. The challenge tests for proof of chemical sensitivity include inhaled toxics within a clean booth that is chemical- and particulate-free at ambient doses in parts per million (ppm) or parts per billion (ppb). Individual foods, both organic and commercial (that are contaminated with herbicides and pesticides), are used orally. Water testing and intradermal testing are performed in a less-polluted, controlled environment. These include specific dose injections of molds, dust, and pollen that are preservative-free, individual organic foods, and individual chemicals, i.e. methane, ethane, propane, butane, hexane, formaldehyde, ethanol, car exhaust, jet fuel exhaust, and prosthetic implants (metal plates, pacemakers, mesh, etc.). Normal saline is used as a placebo. EMF testing is performed in a copper-screened room using a frequency generator. In our experience, 80% of the EMF-sensitive patients had chemical sensitivity when studied under less-polluted conditions for particulates, controlled natural gas, pesticides, and chemicals like formaldehyde.

Egg Hypersensitivity and Measles-Mumps-Rubella Vaccine Administration

PEDIATRICS ◽  
1991 ◽  
Vol 88 (5) ◽  
pp. 913-917
Author(s):  
Suzanne A. Beck ◽  
Larry W. Williams ◽  
M. Annette Shirrell ◽  
A. Wesley Burks
Keyword(s):  
Atopic Dermatitis ◽  
Skin Prick Testing ◽  
Skin Testing ◽  
Screening Method ◽  
Negative Control ◽  
Mmr Vaccine ◽  
Double Blind ◽  
Intradermal Testing ◽  
Vaccine Administration ◽  
History Of

Because reports have described egg-sensitive individuals in whom anaphylaxis developed after measles vaccination, current recommendations include delaying administration of egg-derived vaccines until skin testing can be performed. Specifically, the 1988 Red Book recommends skin testing via scratch, prick, or puncture with 1:10 dilution of the vaccine and, if the result is negative, intradermal testing is suggested. The purpose of this study was to evaluate the likelihood of reaction to measles-mumps-rubella (MMR) vaccine in patients with documented egg sensitivity and to delineate the efficacy of skin-prick testing (SPT) to MMR as a predictor of hypersensitivity to the vaccine. Egg sensitivity was documented by initial SPT to egg and then, if possible, double-blind placebo-controlled food challenge (DBPCFC). Patients with a positive DBPCFC to egg or a history of anaphylactic egg sensitivity had a SPT with the MMR vaccine and then were given the MMR vaccine. Additionally, children with atopic dermatitis who had been previously proven egg sensitive via DBPCFCs were evaluated retrospectively for sensitivity to the MMR vaccine. Sixteen children with a history of egg sensitivity underwent SPT to egg, with a positive result 3 mm greater than the negative control found in 12 patients. Eight of these children had a positive DBPCFC to egg. The SPT to MMR vaccine was negative in all 16 children; vaccine administration followed with no resultant systemic problems. Three children had a local reaction at the site of injection. Twelve additional children with atopic dermatitis and egg sensitivity were reviewed. Each child had a positive SPT and DBPCFC to egg. Ten of these children received the MMR vaccine prior to the time that their egg sensitivity was elucidated. Two other children were vaccinated elsewhere after they were documented egg sensitive. All 12 of these children tolerated the vaccine without incident. These results further substantiate the safety of MMR administration in egg-sensitive children and support routine vaccination of children who do not exhibit systemic allergic hypersensitivity to egg. It is suggested that SPT is an adequate screening method for children with anaphylactic egg sensitivity.

scholarly journals The Diagnosis of Acute Anaphylactoid Reactions to Anaesthetic Drugs

1981 ◽  
Vol 9 (3) ◽  
pp. 235-241 ◽  
Author(s):  
M. McD. Fisher
Keyword(s):  
Contrast Media ◽  
No Value ◽  
Anaphylactoid Reaction ◽  
Passive Transfer ◽  
Presumptive Diagnosis ◽  
Intradermal Testing ◽  
Anaphylactoid Reactions ◽  
Transfer Testing ◽  
Made In

Patients with a presumptive diagnosis of an acute anaphylactoid reaction to anaesthesia were investigated to determine the cause of the reaction and the drug responsible by intradermal testing, patch and prick testing, sequential complement measurement, passive transfer testing and challenge. The most valuable information was provided by intradermal testing and a diagnosis could be made in 150 of 165 patients. When anaphylactoid reactions to anaesthetic drugs occur, intradermal testing one month after the reaction and sequential complement measurements in the immediate post reaction period will enable the diagnosis to be established in the majority of cases. Intradermal testing is of no value for trivial reactions or reactions to colloid solutions or contrast media.

IgG Levels after Treatment with Antigen Vials Based on the Scratch Testing, Intradermal Testing, Modified RAST Testing

1986 ◽  
Vol 95 (3_part_1) ◽  
pp. 307-311 ◽  
Author(s):  
Richard J. Trevino
Keyword(s):  
Scratch Testing ◽  
Igg Antibody ◽  
Intradermal Testing ◽  
Blocking Antibody ◽  
Multiple Treatment ◽  
End Point ◽  
Specific Igg ◽  
Inhalant Allergens ◽  
Inhalant Allergy ◽  
Antibody Levels

In this study, there were three groups of patients—each group consisting of four patients. The first group had been skin tested by the scratch method, the second group was skin tested by the end point titration intradermal method, and the third group had been tested for inhalant allergy by the modified RAST technique. All of them had multiple treatment vials made, dependent on the type of testing they had, and the vials all included the ten inhalants that were tested for. All patients had been treated for a year with weekly immunotherapy injections. Specific IgG levels, blocking antibody levels to the ten inhalant allergens, were determined. The results were that the patients who had been scratch tested had the lowest levels of specific IgG blocking antibody—while both intradermal end point titration and modified RAST testing had much higher elevations of blocking IgG antibody, with the RAST having the highest. It is concluded that, since the treatment vials prepared after scratch testing of all the antigens are at the same concentration, there are many antigens that are not given in adequate amounts to cause a good IgG response whereas, by calibrating the concentrations of antigens in the intradermal titration and the modified RAST testing, all the antigens are being injected in sufficient quantities to get a good blocking antibody response.

OR061 Stratification of peanut-murine model into anaphylaxis severity risk groups using intradermal testing read by thermography

2017 ◽  
Vol 119 (5) ◽  
pp. S7-S8 ◽  
Author(s):  
B. Peppers ◽  
D. Jhaveri ◽  
R. Hostoffer ◽  
T. Bonfield
Keyword(s):  
Murine Model ◽  
Risk Groups ◽  
Intradermal Testing

Contamination of antigens with traces of other antigens as a cause of false positive reactions in intradermal testing

1942 ◽  
Vol 13 (4) ◽  
pp. 380-384 ◽  
Author(s):  
Willard S. Small ◽  
Roland C. Hawes ◽  
Hyman Miller ◽  
George Piness
Keyword(s):  
False Positive ◽  
Intradermal Testing ◽  
False Positive Reactions

Evaluation of the precision of intradermal injection of control substances for intradermal testing in clinically normal horses

2005 ◽  
Vol 66 (8) ◽  
pp. 1341-1347 ◽  
Author(s):  
David M. Wong ◽  
Virginia A. Buechner-Maxwell ◽  
Thomas O. Manning ◽  
Daniel L. Ward
Keyword(s):  
Intradermal Injection ◽  
Intradermal Testing ◽  
Clinically Normal

Association between results of diagnostic tests for bovine tuberculosis and Johne’s disease in cattle

2019 ◽  
Vol 185 (22) ◽  
pp. 693-693 ◽  
Author(s):  
Catalina Picasso-Risso ◽  
Ana Grau ◽  
Douwe Bakker ◽  
Jesus Nacar ◽  
Olga Mínguez ◽  
...  
Keyword(s):  
Bovine Tuberculosis ◽  
Diagnostic Tests ◽  
Conditional Logistic Regression ◽  
Johne's Disease ◽  
Johne’S Disease ◽  
Effective Control ◽  
Mixed Effect ◽  
Intradermal Testing ◽  
Herd Level ◽  
The Impact

BackgroundBovine tuberculosis (bTB) diagnosis is impaired by numerous factors including cross-reactivity with Mycobacterium avium subspecies paratuberculosis, which causes Johne’s disease (JD). In addition, the effect of repeated bTB-intradermal testing on the performance of JD diagnostic tests is not fully understood. This study aimed to evaluate the impact of repeated bTB-intradermal tests under field conditions in Spain on the JD serological status of cattle.MethodsbTB-positive herds (n=264) from Castilla-y-Leon region were selected and matched with officially tuberculosis-free control herds. The association between JD and bTB status at the herd level was assessed using conditional logistic regression and, in herds with both JD-positive and bTB-positive animals, a Bayesian hierarchical mixed-effect model was used for individual-level analysis.ResultsA significantly higher risk of being JD positive (OR: 1.48; 95 per cent CI: 1.01 to 2.15) was found for bTB-positive herds compared with controls. Individual results indicated that cattle tested more than three times per year, within the last 90 days and more than 12 months were more likely to be JD positive. A skin test-related boost in antibody response could be the cause of an apparent increase of the sensitivity of the JD-absorbed ELISA.ConclusionThe results demonstrate the interaction between bTB repeated testing and JD individual and herd-level results and this improved knowledge will facilitate the design of more effective control programmes in herds coinfected with two of the most important endemic diseases affecting cattle in Spain.

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