3D‐printed bone models for planning and training in oral and cranio‐maxillofacial surgery‐ a systematic review

Abstract Aim This systematic review aimed to evaluate the use of three-dimensional (3D) printed bone models for training, simulating and/or planning interventions in oral and cranio-maxillofacial surgery. Materials and methods A systematic search was conducted using PubMed® and SCOPUS® databases, up to March 10, 2019, by following the Preferred Reporting Items for Systematic reviews and Meta-Analysis (PRISMA) protocol. Study selection, quality assessment (modified Critical Appraisal Skills Program tool) and data extraction were performed by two independent reviewers. All original full papers written in English/French/Italian and dealing with the fabrication of 3D printed models of head bone structures, designed from 3D radiological data were included. Multiple parameters and data were investigated, such as author’s purpose, data acquisition systems, printing technologies and materials, accuracy, haptic feedback, variations in treatment time, differences in clinical outcomes, costs, production time and cost-effectiveness. Results Among the 1157 retrieved abstracts, only 69 met the inclusion criteria. 3D printed bone models were mainly used as training or simulation models for tumor removal, or bone reconstruction. Material jetting printers showed best performance but the highest cost. Stereolithographic, laser sintering and binder jetting printers allowed to create accurate models with adequate haptic feedback. The cheap fused deposition modeling printers exhibited satisfactory results for creating training models. Conclusion Patient-specific 3D printed models are known to be useful surgical and educational tools. Faced with the large diversity of software, printing technologies and materials, the clinical team should invest in a 3D printer specifically adapted to the final application.

Download Full-text

Clinical efficacy and effectiveness of 3D printing: a systematic review

BMJ Open ◽

10.1136/bmjopen-2017-016891 ◽

2017 ◽

Vol 7 (12) ◽

pp. e016891 ◽

Cited By ~ 47

Author(s):

Laura E Diment ◽

Mark S Thompson ◽

Jeroen H M Bergmann

Keyword(s):

Systematic Review ◽

3D Printing ◽

Clinical Efficacy ◽

Musculoskeletal System ◽

Preoperative Planning ◽

Maxillofacial Surgery ◽

Oral And Maxillofacial Surgery ◽

Level Of Evidence ◽

Standard Clinical Practice ◽

3D Printed

ObjectiveTo evaluate the clinical efficacy and effectiveness of using 3D printing to develop medical devices across all medical fields.DesignSystematic review compliant with Preferred Reporting Items for Systematic Reviews and Meta-Analyses.Data sourcesPubMed, Web of Science, OVID, IEEE Xplore and Google Scholar.MethodsA double-blinded review method was used to select all abstracts up to January 2017 that reported on clinical trials of a three-dimensional (3D)-printed medical device. The studies were ranked according to their level of evidence, divided into medical fields based on the International Classification of Diseases chapter divisions and categorised into whether they were used for preoperative planning, aiding surgery or therapy. The Downs and Black Quality Index critical appraisal tool was used to assess the quality of reporting, external validity, risk of bias, risk of confounding and power of each study.ResultsOf the 3084 abstracts screened, 350 studies met the inclusion criteria. Oral and maxillofacial surgery contained 58.3% of studies, and 23.7% covered the musculoskeletal system. Only 21 studies were randomised controlled trials (RCTs), and all fitted within these two fields. The majority of RCTs were 3D-printed anatomical models for preoperative planning and guides for aiding surgery. The main benefits of these devices were decreased surgical operation times and increased surgical accuracy.ConclusionsAll medical fields that assessed 3D-printed devices concluded that they were clinically effective. The fields that most rigorously assessed 3D-printed devices were oral and maxillofacial surgery and the musculoskeletal system, both of which concluded that the 3D-printed devices outperformed their conventional comparators. However, the efficacy and effectiveness of 3D-printed devices remain undetermined for the majority of medical fields. 3D-printed devices can play an important role in healthcare, but more rigorous and long-term assessments are needed to determine if 3D-printed devices are clinically relevant before they become part of standard clinical practice.

Download Full-text

SURGICAL OUTCOMES OF 3D PRINTED MUSCULOSKELETAL METAL IMPLANTS: A SYSTEMATIC REVIEW

Journal of Musculoskeletal Research ◽

10.1142/s0218957718400018 ◽

2018 ◽

Vol 21 (03n04) ◽

pp. 1840001

Author(s):

C. Dion ◽

M. Pollock ◽

J. Howard ◽

L. Somerville ◽

B. Lanting

Keyword(s):

Systematic Review ◽

3D Printing ◽

Surgical Outcomes ◽

Maxillofacial Surgery ◽

Case Series ◽

Free Form ◽

Bibliographic Databases ◽

Surgical Practice ◽

Metal Implants ◽

3D Printed

Introduction: Additive manufacturing, also known as 3D printing (3DP), is becoming increasingly available to surgeons throughout the world due to recent advancements in technology. 3D printing can produce complex free-form structures that would be impossible using conventional subtractive manufacturing. This offers the possibility to create implants that are better suited to the irregular anatomic shapes found in the human body. The present study aims to examine the surgical outcomes associated with the use of 3D printed metal implants and uncover the value of 3D printing in musculoskeletal surgery. Methods: A systematic review of published literature was performed in June 2017 using the PRISMA protocol. Online bibliographic databases such as MEDLINE, Embase, Scopus, CINAHL, and Cochrane were used to identify studies involving surgical implantation of 3D printed metal implants in musculoskeletal surgery. References from relevant studies were scanned for additional articles. Two reviewers independently screened results. Full-text articles were analyzed for eligibility. A total of 24 studies were included for data abstraction. Results were collected and qualitatively analyzed. Results: Of the 25 articles included, there were 17 case reports, 4 case series, 2 retrospective cohorts and 3 prospective cohorts. Of these articles, the majority of 3DP was done with electron beam melting (EBM) with Ti6Al4V. Orthopaedic, neurosurgical, plastic, and maxillofacial surgery articles were included in the review. All studies concluded that 3D printed implants had favourable post-operative outcomes. Some advantages included the reduction of operative time, improved osseointegration through custom implant porosity, improved fixation, decreased stress shielding, better cosmetic appearance, improved functional outcome, and limb salvage. Additional cost and time required to design and print the implants were reported as potential drawbacks to 3D printing. Discussion/Conclusions. The applications of 3D printing in musculoskeletal surgery are promising and have the potential to alter future surgical practice. However, there is a lack of quality research in the literature assessing the use of 3D printed implants. Further research is needed to evaluate the use of 3D printing in musculoskeletal surgery to understand its potential effects on surgical practice.

Download Full-text

Motor Performance in Male Youth Soccer Players: A Systematic Review of Longitudinal Studies

Sports ◽

10.3390/sports9040053 ◽

2021 ◽

Vol 9 (4) ◽

pp. 53

Author(s):

Maryam Abarghoueinejad ◽

Adam D. G. Baxter-Jones ◽

Thayse Natacha Gomes ◽

Daniel Barreira ◽

José Maia

Keyword(s):

Systematic Review ◽

Longitudinal Data ◽

Motor Performance ◽

Longitudinal Design ◽

Soccer Players ◽

Male Youth ◽

European Continent ◽

Young Males ◽

Performance Improvements ◽

And Training

The aim of this systematic review was to identify and synthesize the available information regarding longitudinal data addressing young soccer players’ motor performance changes. Following the Preferred Reporting Items for Systematic and Meta-analyses (PRISMA) statement, literature searches were performed in three databases: PubMed, ISI Web of Science and SCOPUS. The following descriptors were used: football, soccer, youth, young, player, athlete, physical performance, motor performance, longitudinal. The inclusion criteria were original articles in English with longitudinal data of young males (aged 10–18 years), with the aim to investigate motor performance serial changes. The initial search returned 211 records, and the final sample comprised 32 papers. These papers covered the European continent, and used mixed and pure longitudinal design with variation in sample size and age range. The reviewed studies tended to use different tests to assess the motor performance and aimed to identify changes in motor performance in several ways. In general, they indicated motor performance improvements with age, with a marked influence of biological maturity, body composition, and training stimuli. This review highlights the need for coaches and stakeholders to consider players’ motor performance over time whilst considering biological maturation, biological characteristics, and training stimuli.

Download Full-text

Main Approaches to the Use of Biomaterials in Oral and Maxillofacial Surgery: A Brief Systematic Review

MedNEXT Journal of Medical and Health Sciences ◽

10.34256/mdnt2127 ◽

2021 ◽

pp. 42-48

Author(s):

Henrique Esteves Magalhães ◽

Priscilla Janaína de Lima Borelli Bovo ◽

Luciano Rodrigues Neves ◽

Marcelo Henrique Batista Santos ◽

Rogério Luiz de Araújo Vian ◽

...

Keyword(s):

Systematic Review ◽

Bone Tissue ◽

Dental Implants ◽

Bone Growth ◽

Maxillofacial Surgery ◽

Oral And Maxillofacial Surgery ◽

Success Rates ◽

Dental Implantation ◽

Regeneration Of Bone Tissue ◽

Regeneration Of Bone

Introduction: In recent years, procedures with the use of dental implants have increased worldwide, reaching approximately one million dental implants per year. In recent years, a platelet concentrate called FRP (fibrin-rich plasma) has been the subject of clinical studies. Associated with this, the biomaterial Bio-Oss® (Geistlich), as it is biodegradable, biocompatible, non-toxic, and has low immunogenicity, and bio stimulators can act in the regeneration of bone tissue, as it establishes with the cells the appropriate biological niche (favorable microenvironment) for bone growth. Objective: Therefore, the present study aimed to evaluate, through a brief systematic review, the results that involve bone formation for dental implantation, with the use of biomaterials such as fibrin-rich plasma and Bio-Oss®. Methods: The model used for the review was PRISMA. Was used databases such as Scopus, Scielo, Lilacs, Google Scholar, PubMed. Results: Fibrin-rich plasma (FRP) as an autologous biomaterial for use in oral and maxillofacial surgery presents most leukocytes, platelets, and growth factors, forming a fibrin matrix, with three-dimensional architecture. The Bio-Oss® biomaterial (Geistlich), as it is biodegradable, biocompatible, non-toxic, and has low immunogenicity and bio stimulators can act in the regeneration of bone tissue, since it establishes with the adenomatous mesenchymal stem cells the appropriate biological niche for bone growth and, thus, allowing the dental implant to be as effective as possible. Conclusion: The use of FRP associated with Bio-Oss® seems to illustrate high success rates with minimal costs, which may reduce the amount of bone graft needed to fill the sinus cavity, reducing the costs of the procedure.

Download Full-text

A Systematic Review of Differences Between Conventional Orthoses and 3D-Printed Orthoses

Advances in Manufacturing, Production Management and Process Control - Lecture Notes in Networks and Systems ◽

10.1007/978-3-030-80462-6_7 ◽

2021 ◽

pp. 53-60

Author(s):

Ana Cláudia Tavares Rodrigues ◽

Letícia Vasconcelos Morais Garcez ◽

Fausto Orsi Medola ◽

Luciana Ramos Baleotti ◽

Frode Eika Sandnes ◽

...

Keyword(s):

Systematic Review ◽

3D Printed

Download Full-text

Antibiotic prophylaxis in oral and maxillofacial surgery: a systematic review

British Journal of Oral and Maxillofacial Surgery ◽

10.1016/j.bjoms.2020.09.020 ◽

2020 ◽

Author(s):

Tihana Milic ◽

Priyanka Raidoo ◽

Dieter Gebauer

Keyword(s):

Systematic Review ◽

Antibiotic Prophylaxis ◽

Maxillofacial Surgery ◽

Oral And Maxillofacial Surgery

Download Full-text

In Vitro Mechanical and Biological Properties of 3D Printed Polymer Composite and β-Tricalcium Phosphate Scaffold on Human Dental Pulp Stem Cells

Materials ◽

10.3390/ma13143057 ◽

2020 ◽

Vol 13 (14) ◽

pp. 3057 ◽

Cited By ~ 2

Author(s):

Shuaishuai Cao ◽

Jonghyeuk Han ◽

Neha Sharma ◽

Bilal Msallem ◽

Wonwoo Jeong ◽

...

Keyword(s):

Stem Cells ◽

Tricalcium Phosphate ◽

Dental Pulp ◽

Chemical Elements ◽

Maxillofacial Surgery ◽

3D Structure ◽

Dental Pulp Stem Cells ◽

Oral And Maxillofacial Surgery ◽

Human Dental Pulp ◽

3D Printed

3D printed biomaterials have been extensively investigated and developed in the field of bone regeneration related to clinical issues. However, specific applications of 3D printed biomaterials in different dental areas have seldom been reported. In this study, we aimed to and successfully fabricated 3D poly (lactic-co-glycolic acid)/β-tricalcium phosphate (3D-PLGA/TCP) and 3D β-tricalcium phosphate (3D-TCP) scaffolds using two relatively distinct 3D printing (3DP) technologies. Conjunctively, we compared and investigated mechanical and biological responses on human dental pulp stem cells (hDPSCs). Physicochemical properties of the scaffolds, including pore structure, chemical elements, and compression modulus, were characterized. hDPSCs were cultured on scaffolds for subsequent investigations of biocompatibility and osteoconductivity. Our findings indicate that 3D printed PLGA/TCP and β-tricalcium phosphate (β-TCP) scaffolds possessed a highly interconnected and porous structure. 3D-TCP scaffolds exhibited better compressive strength than 3D-PLGA/TCP scaffolds, while the 3D-PLGA/TCP scaffolds revealed a flexible mechanical performance. The introduction of 3D structure and β-TCP components increased the adhesion and proliferation of hDPSCs and promoted osteogenic differentiation. In conclusion, 3D-PLGA/TCP and 3D-TCP scaffolds, with the incorporation of hDPSCs as a personalized restoration approach, has a prospective potential to repair minor and critical bone defects in oral and maxillofacial surgery, respectively.

Download Full-text

A Systematic Review of the Clinical Value and Applications of Three-Dimensional Printing in Renal Surgery

Journal of Clinical Medicine ◽

10.3390/jcm8070990 ◽

2019 ◽

Vol 8 (7) ◽

pp. 990 ◽

Cited By ~ 8

Author(s):

Catalina Lupulescu ◽

Zhonghua Sun

Keyword(s):

Systematic Review ◽

3D Printing ◽

Renal Disease ◽

User Satisfaction ◽

Surgical Simulation ◽

Case Reports ◽

Time Duration ◽

Printing Process ◽

Estimated Blood Loss ◽

3D Printed

The purpose of this systematic review is to collate and analyse the current literature which examines clinical applications of 3D printing for renal disease, alongside cost and time duration factors associated with the printing process. A comprehensive search of the literature was performed across five different databases to identify studies that qualitatively and quantitatively assessed the value of 3D-printed kidney models for renal disease. Twenty-seven studies met the selection criteria for inclusion in the review. Twenty-five were original studies, and two were case reports. Of the 22 studies reporting a qualitative evaluation, the analysis of findings demonstrated the value of the 3D-printed models in areas of clinician and patient education, and pre-surgical simulation for complex cases of renal disease. Of five studies performing a quantitative analysis, the analysis of results displayed a high level of spatial and anatomical accuracy amongst models, with benefits including reducing estimated blood loss and risk of intra-operative complications. Fourteen studies evaluated manufacturing costs and time duration, with costs ranging from USD 1 to 1000 per model, and time duration ranging from 15 min to 9 days. This review shows that the use of customised 3D-printed models is valuable in the education of junior surgeons as well as the enhancement of operative skills for senior surgeons due to a superior visualisation of anatomical networks and pathologic morphology compared to volumetric imaging alone. Furthermore, 3D-printed kidney models may facilitate interdisciplinary communication and decision-making regarding the management of patients undergoing operative treatment for renal disease. It cannot be suggested that a more expensive material constitutes a higher level of user-satisfaction and model accuracy. However, higher costs in the manufacturing of the 3D-printed models reported, on average, a slightly shorter time duration for the 3D-printing process and total manufacturing time.

Download Full-text