scholarly journals Enhanced osseointegration in osteogenic nanofibrous coated titanium implant in rabbit - a pilot study

2018 ◽  
Vol 29 ◽  
pp. 127-127
Author(s):  
Kanchan Dholam ◽  
Sandeep Gurav
Keyword(s):  
2010 ◽  
Vol 36 (5) ◽  
pp. 357-362 ◽  
Author(s):  
Young-Seok Park ◽  
Seung-Pyo Lee ◽  
Chong-Hyun Han ◽  
Joo Hyun Kwon ◽  
Young-Chul Jung

Abstract This study was undertaken to evaluate the effect of microthread geometry of scalloped design implant on marginal bone resorption. Four types of scalloped design titanium implant specimens were prepared. The type 1 implant had a machined scalloped collar, type 2 had a sandblasted and acid-etched scalloped collar, type 3 had horizontal microthreads, and type 4 had parabolic microthreads, which are parallel with the scalloped conical margin. Two implants of a type were randomly installed immediately after extraction in the mandible of a beagle dog. Definitive prostheses were delivered immediately after surgery. After 12 weeks of healing, the dog was sacrificed and microtomography was performed. Type 4 specimens showed a marginal bone loss pattern definitively analogous to the scalloped margin. In this preliminary study, microthread geometry affected the marginal bone resorption pattern of scalloped design implants. However, additional specimens and more controlled conditions should be applied in future studies to confirm these results.


2019 ◽  
Vol 21 (6) ◽  
pp. 1175-1180
Author(s):  
Guilherme dos Santos Trento ◽  
Rubens Spin‐Neto ◽  
Ana Paula Farnezi Bassi ◽  
Roberta Okamoto ◽  
Marisa Aparecida Cabrini Gabrielli ◽  
...  

2012 ◽  
Vol 21 (6) ◽  
pp. 454-460 ◽  
Author(s):  
Luca Gobbato ◽  
Emilio Arguello ◽  
Ignacio Sanz Martin ◽  
Charles E. Hawley ◽  
Terrence J. Griffin

2014 ◽  
Vol 29 (2) ◽  
pp. 338-343 ◽  
Author(s):  
Yeliz Cavusoglu ◽  
Kıvanç Akça ◽  
Rıza Gürbüz ◽  
Murat Cavit Cehreli

2012 ◽  
Vol 2012 ◽  
pp. 1-9 ◽  
Author(s):  
Ester Orsini ◽  
Stefano Salgarello ◽  
Désirée Martini ◽  
Beatrice Bacchelli ◽  
Marilisa Quaranta ◽  
...  

In the present pilot study, the authors morphologically investigated sandblasted, acid-etched surfaces (SLA) at very early experimental times. The tested devices were titanium plate-like implants with flattened wide lateral sides and jagged narrow sides. Because of these implant shape and placement site, the device gained a firm mechanical stability but the largest portion of the implant surface lacked direct contact with host bone and faced a wide peri-implant space rich in marrow tissue, intentionally created in order to study the interfacial interaction between metal surface and biological microenvironment. The insertion of titanium devices into the proximal tibia elicited a sequence of healing events. Newly formed bone proceeded through an early distance osteogenesis, common to both surfaces, and a delayed contact osteogenesis which seemed to follow different patterns at the two surfaces. In fact, SLA devices showed a more osteoconductive behavior retaining a less dense blood clot, which might be earlier and more easily replaced, and leading to a surface-conditioning layer which promotes osteogenic cell differentiation and appositional new bone deposition at the titanium surface. This model system is expected to provide a starting point for further investigations which clarify the early cellular and biomolecular events occurring at the metal surface.


2015 ◽  
Vol 2015 ◽  
pp. 1-11 ◽  
Author(s):  
Nam-Ho Kim ◽  
So-Hyoun Lee ◽  
Jae-Jun Ryu ◽  
Kyung-Hee Choi ◽  
Jung-Bo Huh

This study was conducted to evaluate effects of rhBMP-2 applied at different concentrations to sandblasted and acid etched (SLA) implants on osseointegration and bone regeneration in a bone defect of beagle dogs as pilot study using split-mouth design.Methods. For experimental groups, SLA implants were coated with different concentrations of rhBMP-2 (0.1, 0.5, and 1 mg/mL). After assessment of surface characteristics and rhBMP-2 releasing profile, the experimental groups and untreated control groups (n= 6 in each group, two animals in each group) were placed in split-mouth designed animal models with buccal open defect. At 8 weeks after implant placement, implant stability quotients (ISQ) values were recorded and vertical bone height (VBH, mm), bone-to-implant contact ratio (BIC, %), and bone volume (BV, %) in the upper 3 mm defect areas were measured.Results. The ISQ values were highest in the 1.0 group. Mean values of VBH (mm), BIC (%), and BV (%) were greater in the 0.5 mg/mL and 1.0 mg/mL groups than those in 0.1 and control groups in buccal defect areas.Conclusion. In the open defect area surrounding the SLA implant, coating with 0.5 and 1.0 mg/mL concentrations of rhBMP-2 was more effective, compared with untreated group, in promoting bone regeneration and osseointegration.


Author(s):  
J. E. Laffoon ◽  
R. L. Anderson ◽  
J. C. Keller ◽  
C. D. Wu-Yuan

Titanium (Ti) dental implants have been used widely for many years. Long term implant failures are related, in part, to the development of peri-implantitis frequently associated with bacteria. Bacterial adherence and colonization have been considered a key factor in the pathogenesis of many biomaterial based infections. Without the initial attachment of oral bacteria to Ti-implant surfaces, subsequent polymicrobial accumulation and colonization leading to peri-implant disease cannot occur. The overall goal of this study is to examine the implant-oral bacterial interfaces and gain a greater understanding of their attachment characteristics and mechanisms. Since the detailed cell surface ultrastructure involved in attachment is only discernible at the electron microscopy level, the study is complicated by the technical problem of obtaining titanium implant and attached bacterial cells in the same ultra-thin sections. In this study, a technique was developed to facilitate the study of Ti implant-bacteria interface.Discs of polymerized Spurr’s resin (12 mm x 5 mm) were formed to a thickness of approximately 3 mm using an EM block holder (Fig. 1). Titanium was then deposited by vacuum deposition to a film thickness of 300Å (Fig. 2).


1973 ◽  
Vol 37 (11) ◽  
pp. 27-31 ◽  
Author(s):  
G Salvendy ◽  
WM Hinton ◽  
GW Ferguson ◽  
PR Cunningham

Sign in / Sign up

Export Citation Format

Share Document