Prognostic significance of apical lymph node metastasis in patients with node-positive rectal cancer

The sentinel node procedure is an adequate tool to identify lymph node metastasis in breast cancer. Sentinel nodes are generally examined with greater attention mainly to exclude, as reliably as possible, lymph node metastasis. To achieve this, many protocols are used, resulting in different rates of micrometastasis or isolated tumor cells encountered. Since the prognostic significance of isolated tumor cells or micrometastasis in the sentinel nodes, and the risk of further axillary lymph node involvement in patients with isolated tumor cells, is uncertain and at most limited, these findings may pose difficulties for clinicians in clinical decision making. Protocols that identify lymph node metastasis, from which the clinical relevance is known, are warranted. Unnecessary lymph node dissections should be avoided.

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Prognostic significance of lymph node metastasis and bone, major vessel, or nerve involvement in adults with high-grade soft tissue sarcomas

Cancer ◽

10.1002/1097-0142(19880901)62:5<999::aid-cncr2820620527>3.0.co;2-n ◽

1988 ◽

Vol 62 (5) ◽

pp. 999-1006 ◽

Cited By ~ 37

Author(s):

Wlodzimierz Ruka ◽

Lawrence J. Emrich ◽

Deborah L. Driscoll ◽

Constantine P. Karakousis

Keyword(s):

Lymph Node ◽

Soft Tissue ◽

Lymph Node Metastasis ◽

Prognostic Significance ◽

Soft Tissue Sarcomas ◽

High Grade ◽

Node Metastasis ◽

Nerve Involvement ◽

Major Vessel

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The prognostic significance of lymph node metastasis and intrapancreatic perineural invasion in pancreatic cancer after curative resection

Surgery Today ◽

10.1007/bf02482964 ◽

1999 ◽

Vol 29 (1) ◽

pp. 16-22 ◽

Cited By ~ 100

Author(s):

Hideo Ozaki ◽

Takehisa Hiraoka ◽

Ryuji Mizumoto ◽

Seiki Matsuno ◽

Yoshiro Matsumoto ◽

...

Keyword(s):

Pancreatic Cancer ◽

Lymph Node ◽

Lymph Node Metastasis ◽

Curative Resection ◽

Perineural Invasion ◽

Prognostic Significance ◽

Node Metastasis

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Vas deferens invasion: A neglected issue in the sampling of radical prostatectomy materials

Canadian Urological Association Journal ◽

10.5489/cuaj.1802 ◽

2014 ◽

Vol 8 (7-8) ◽

pp. 554 ◽

Cited By ~ 3

Author(s):

Nuri Yigit ◽

Yildirim Karslioglu ◽

Bulent Kurt

Keyword(s):

Lymph Node ◽

Radical Prostatectomy ◽

Lymph Node Metastasis ◽

Vas Deferens ◽

Prognostic Significance ◽

Seminal Vesicles ◽

Node Metastasis ◽

Increased Risk ◽

Staging Systems ◽

Independent Prognostic Significance

A radical prostatectomy affects the prostate, bilateral seminal vesicles (SV), and the distal parts of the bilateral vasa deferentia (VD). SV invasion (SVI) is associated with an increased risk of lymph node metastasis and recurrence. However, the significance of VD invasion (VDI), either with or without the involvement of their surgical margins, has not been fully appreciated. We think VDI might have an independent prognostic significance, as does SVI, and should be incorporated into the pathology guidelines and the staging systems of prostatic adenocarcinoma. Our case illustrates this.

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