Increased technetium-99 m hydroxy diphosphonate soft tissue uptake on bone scintigraphy in chronic kidney disease patients with secondary hyperparathyroidism: correlation with hyperphosphataemia

2015 ◽  
Vol 37 (2) ◽  
pp. 131-136 ◽  
Author(s):  
Lotte Hahn Enevoldsen ◽  
James Heaf ◽  
Liselotte Højgaard ◽  
Bo Zerahn ◽  
Philip Hasbak
2020 ◽  
Vol 8 (3) ◽  
pp. e001197
Author(s):  
Elzbieta Barczak ◽  
Erin O'Connell ◽  
Jeremy R Mortier

A nine-month-old female entire Rottweiler was presented for further investigation of progressive, symmetric facial swelling over the maxilla of four weeks duration. Biochemistry revealed severe azotaemia with hyperphosphataemia. CT revealed poor mineralisation of the facial and calvarial bones. The maxillary and palatine bones were replaced by proliferative, heterogeneous tissue of mixed soft tissue and granular mineral attenuating material. On ultrasound, parathyroid glands were enlarged and renal lesions suggestive of juvenile nephropathy were observed. Due to poor long-term prognosis, the owner elected euthanasia. Necropsy confirmed generalised osteopenia and chronic kidney disease. Renal secondary hyperparathyroidism was diagnosed and should be considered a differential for bilateral facial swelling in young dogs.


Author(s):  
Flavia Ramos de Siqueira ◽  
Karin Carneiro de Oliveira ◽  
Wagner Vasques Dominguez ◽  
César Augusto Madid Truyts ◽  
Rosa Maria Affonso Moysés ◽  
...  

2017 ◽  
Vol 10 (10) ◽  
pp. 1073-1084 ◽  
Author(s):  
Andrea Galassi ◽  
Antonio Bellasi ◽  
Paola Ciceri ◽  
Francesca Pivari ◽  
Ferruccio Conte ◽  
...  

2019 ◽  
Vol 6 (2) ◽  
pp. 271
Author(s):  
Vishnu Shankar H. ◽  
Mahendra Kumar K. ◽  
Jagadeesan M. ◽  
Kannan R. ◽  
Chitrambalam P. ◽  
...  

Background: Secondary hyperparathyroidism (SHPT) is one of the less recognized complications in patients with chronic kidney disease (CKD). The prevalence of SHPT in various stages of CKD was evaluated by measuring the levels of intact parathyroid hormone (iPTH).Methods: This cross-sectional study was carried out in 100 CKD patients. Serum creatinine, calcium, phosphorous and iPTH levels were measured and statistical analysis was carried out using the SPSS software (IBM, NY, USA).Results: Among the 100 participants, the mean age (SD) was 59.3 (7.8) years. In our study population, 52% were men and the rest were females. Hypertension (75%) was the most common chronic morbidity. Prevalence of hyperparathyroidism among chronic kidney disease patients was 22% (95% CI: 14.7-30.9%). The prevalence of secondary hyperparathyroidism among dialysis and non-dialysis patients were 30% and 14% respectively which was statistically significant.Conclusions: SHPT is an important complication which is often underdiagnosed. Secondary hyperparathyroidism starts to develop when eGFR falls below 60ml/min. PTH levels starts to rise as the disease progress. Hence it is important for the treating physicians to monitor the PTH levels early in the course of CKD to prevent and treat bone mineral disease.


Author(s):  
Giovanni FM Strippoli ◽  
Allison Tong ◽  
Suetonia C Palmer ◽  
Grahame J Elder ◽  
Jonathan C Craig

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