The relationship between presystolic wave and subclinical left ventricular dysfunction assessed by myocardial performance ındex in patients with polycystic ovary syndrome

2021 ◽  
Author(s):  
Faysal Saylik ◽  
Tayyar Akbulut
2013 ◽  
Vol 62 (18) ◽  
pp. C177
Author(s):  
Ercan Erdoğan ◽  
Mehmet Akkaya ◽  
Ahmet Bacaksız ◽  
Abdurrahman Tasal ◽  
Seref Kul ◽  
...  

2015 ◽  
Vol 10 (1) ◽  
pp. 3-6
Author(s):  
Samsun Nahar ◽  
Choudhury Meshkat Ahmed ◽  
Md Abu Siddique ◽  
Tanjima Parveen ◽  
Shiblee Sadeque Shakil ◽  
...  

In diabetes mellitus (DM) patients, left ventricular dysfunction is widely evaluated and established by conventional diagnostic methods, whereas right ventricular (RV) function is not sufficiently evaluated. The aim of this study was to assess the right ventricular function in type 2 diabetic patients by myocardial performance index (MPI) . In this cross-sectional study, 49 diabetic patients and 49 non-diabetic healthy volunteers were studied who were devoid of any other conditions that may influence the both systolic and diastolic function of the RV. In addition to 2D and M-mode evaluation, standard Doppler, pulsed tissue Doppler of both ventricles were performed. MPI was significantly (p<0.05) higher in diabetic patients compared to control group . Right ventricular early diastolic velocity (E‘) and late diastolic velocity (A‘), E‘/A‘ were significantly (p<0.05) lower in DM compared to control group. Myocardial performance index is a useful noninvasive tool for the detection of early right ventricular systolic and diastolic dysfunction in diabetic patients .University Heart Journal Vol. 10, No. 1, January 2014; 3-6


2005 ◽  
Vol 60 (4) ◽  
pp. 415-420 ◽  
Author(s):  
Mustafa OZKAN ◽  
Mehmet UZUN ◽  
Kursad ERINC ◽  
Cem KOZ ◽  
Oben BAYSAN ◽  
...  

Author(s):  
Zora Lazúrová ◽  
Jana Figurová ◽  
Beáta Hubková ◽  
Jana Mašlanková ◽  
Ivica Lazúrová

Abstract Objectives There is a growing evidence indicating an impact of endocrine distrupting chemicals such as bisphenol A (BPA) on human reproduction. Its higher levels in serum or urine have been documented in women with polycystic ovary syndrome (PCOS), however the relationship to ovarian steroidogenesis remains unclear. Aim of the study was to compare urinary BPA (U-BPA) concentrations among PCOS women and control group. Second aim was to assess the relationship of U-BPA to ovarian steroidogenesis in the group with PCOS. Methods Eighty six Caucasian women (age 28.5 ± 5.1 years) diagnosed with PCOS and 32 controls of age 24.9 ± 4.4 years were included in the study. Fasting blood samples were analyzed for biochemical parameters and steroid hormones. U-BPA was measured in the morning urine sample using high pressure liquid chromatography. Results PCOS women had significantly higher U-BPA as compared with control group (p=0.0001). Those with high levels of U-BPA (U-BPA ≥2.14 ug/g creatinine) demonstrated higher serum insulin (p=0.029) and HOMA IR (p=0.037), lower serum estrone (p=0.05), estradiol (p=0.0126), FSH (p=0.0056), and FAI (p=0.0088), as compared with low-BPA group (U- BPA <2.14 ug/g creatinine). In PCOS women, U-BPA positively correlated with age (p=0.0026; R2=0.17), negatively with estradiol (p=0.0001, R2=0.5), testosterone (p=0.0078, R2=0.15), free-testosterone (p=0.0094, R2=0.12) and FAI (p=0.0003, R2=0.32), respectively. Conclusions PCOS women have significantly higher U-BPA concentrations than healthy controls. U-BPA positively correlates with age and negatively with ovarian steroid hormones suggesting a possible suppressive effect of bisphenol A on ovarian steroidogenesis.


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