scholarly journals The impact of volume substitution on post‐operative atrial fibrillation

Author(s):  
Sebastian Schnaubelt ◽  
Arnold Pilz ◽  
Lorenz Koller ◽  
Niema Kazem ◽  
Felix Hofer ◽  
...  
2015 ◽  
Vol 22 (11) ◽  
pp. 1438-1442
Author(s):  
Ghulam Hussain ◽  
Naseem Ahmad ◽  
Sara Zaheer ◽  
Mirza Ahmad Raza Baig

Atrial fibrillation is the most common arrhythmia observed following CoronaryArtery Bypass Graft surgery. Objectives: To determine the incidence of post-operative atrialfibrillation in patients undergoing coronary artery bypass grafting. Materials and Methods:Study Design: Non-randomized prospective. Setting: Cardiac Surgery Department ofMultan Institute of Cardiology, Multan. Period: 20-1-2014 to 01-05-2015. A total number offour hundred and ninety (490) patients having age more than 40 years undergoing isolatedcoronary artery bypass graft surgery were included in the study. Data was analyzed in SPSSV20 software. Frequency and percentages were used for Atrial Fibrillation. To see the impact ofAF on morbidity, patients developing AF was compared with those who do not develop AtrialFibrillation post-operatively using independent sample t-test for quantitative variables. Chisquaretest and Fischer’s Exact test (whenever appropriate) was used to compare qualitativevariables. Results: A total number of four hundred and ninety (490) patients were included inthis study. There were more 431 males (88.0%) in this study. of the patients 71.6% were in LVGrade I before surgery. Incidence of post-operative atrial fibrillation was 13.5%. In 4.5% patientsIABP was inserted due to hemodynamic instability. Ventilation time and hospital stay time wassignificantly higher in patients with AF postoperatively (p value 0.03 and 0.02 respectively).But duration of inotropic support, post-op CKMB levels and IABP use were not significantlydifferent in both groups. Conclusion: The incidence of post-operative Atrial Fibrillation is 13.5%according to this study. And these patients were associated with increased risk of morbidity.


2020 ◽  
Vol 28 ◽  
Author(s):  
Valeria Visco ◽  
Germano Junior Ferruzzi ◽  
Federico Nicastro ◽  
Nicola Virtuoso ◽  
Albino Carrizzo ◽  
...  

Background: In the real world, medical practice is changing hand in hand with the development of new Artificial Intelligence (AI) systems and problems from different areas have been successfully solved using AI algorithms. Specifically, the use of AI techniques in setting up or building precision medicine is significant in terms of the accuracy of disease discovery and tailored treatment. Moreover, with the use of technology, clinical personnel can deliver a very much efficient healthcare service. Objective: This article reviews AI state-of-the-art in cardiovascular disease management, focusing on diagnostic and therapeutic improvements. Methods: To that end, we conducted a detailed PubMed search on AI application from distinct areas of cardiology: heart failure, arterial hypertension, atrial fibrillation, syncope and cardiovascular rehabilitation. Particularly, to assess the impact of these technologies in clinical decision-making, this research considers technical and medical aspects. Results: On one hand, some devices in heart failure, atrial fibrillation and cardiac rehabilitation represent an inexpensive, not invasive or not very invasive approach to long-term surveillance and management in these areas. On the other hand, the availability of large datasets (big data) is a useful tool to predict the development and outcome of many cardiovascular diseases. In summary, with this new guided therapy, the physician can supply prompt, individualised, and tailored treatment and the patients feel safe as they are continuously monitored, with a significant psychological effect. Conclusion: Soon, tailored patient care via telemonitoring can improve the clinical practice because AI-based systems support cardiologists in daily medical activities, improving disease detection and treatment. However, the physician-patient relationship remains a pivotal step.


2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
A Chikata ◽  
T Kato ◽  
K Ududa ◽  
S Fujita ◽  
K Otowa ◽  
...  

Abstract Introduction Pulmonary vein isolation (PVI) affects ganglionated plexi (GP) around the atrium, leading to a modification of the intrinsic cardiac autonomic system (ANS). In animal models, GP ablation has a potential risk of QT prolongation and ventricular arrhythmias. However, the impact of PVI on QT intervals in humans remains unclear. Purpose This study aims to evaluate the Impact of PVI on QT interval in patients with paroxysmal atrial fibrillation. Methods We analyzed consecutive 117 PAF patients for their first PVI procedures. 12-lead ECG was evaluated at baseline, 4 hr, day 1, 1 month, and 3 months after ablation. Only patients with sinus rhythm on 12-lead ECG at each evaluation point without antiarrhythmic drugs were included. Results Heart rate significantly increased at 4 hr, day 1, and 1 month. Raw QT interval prolonged at 4 hr (417.1±41.6 ms, P<0.001) but shortened at day 1 (376.4±34.1 ms, P<0.001), 1 month (382.2±31.5 ms, P<0.001), and 3 months (385.1±32.8 ms, P<0.001) compared to baseline (391.6±31.4 ms). Bazett- and Fridericia- corrected QTc intervals significantly prolonged at 4hr (Bazett: 430.8±27.9 ms, P<0.001; Fridericia: 425.8±27.4 ms, P<0.001), day1 (Bazett: 434.8±22.3 ms, P<0.001; Fridericia: 414.1±23.7 ms, P<0.001), 1M (Bazett: 434.8±22.3 ms, P<0.001; Fridericia: 408.2±21.0 ms, P<0.05), and 3M (Bazett: 420.1±21.8 ms, P<0.001; Fridericia: 407.8±21.1 ms, P<0.05) compared to baseline (Bazett: 404.9±25.2 ms; Fridericia: 400.0±22.6 ms). On the other hand, Framingham- and Hodges- corrected QTc interval significantly prolonged only at 4hr (Framingham: 424.1±26.6 ms, P<0.001; Hodges: 426.8±28.4 ms, P<0.001) and at day1 (Framingham: 412.3±29.3 ms, P<0.01; Hodges: 410.6±40.2 ms, P<0.05) compared to baseline (Framingham: 399.2±22.7 ms; Hodges: 400.7±22.8 ms). At 4 hr after ablation, raw QT and QTc of all formulas significantly prolonged than baseline. Raw QT and QTc prolongation at 4hr after ablation were more frequently observed in female patients. Multiple regression analysis revealed that female patient is a significant predictor of raw QT and QTc interval prolongation of all formulas 4hr after PVI. Conclusions Raw QT and QTc prolonged after PVI, especially in the acute phase. Female patient is a risk factor for QT prolongation in the acute phase after PVI. Funding Acknowledgement Type of funding source: None


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