scholarly journals Online and offline effects of cerebellar transcranial direct current stimulation on motor learning in healthy older adults: a randomized double-blind sham-controlled study

2017 ◽  
Vol 45 (9) ◽  
pp. 1177-1185 ◽  
Author(s):  
Afshin Samaei ◽  
Fatemeh Ehsani ◽  
Maryam Zoghi ◽  
Mohaddese Hafez Yosephi ◽  
Shapour Jaberzadeh
Keyword(s):  
Older Adults ◽  
Motor Learning ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Controlled Study ◽  
Double Blind ◽  
Healthy Older Adults ◽  
Direct Current Stimulation

scholarly journals Transcranial Direct Current Stimulation Enhances Episodic Memory in Healthy Older Adults by Modulating Retrieval-Specific Activation

2020 ◽  
Vol 2020 ◽  
pp. 1-11
Author(s):  
Lijuan Huo ◽  
Zhiwei Zheng ◽  
Jia Huang ◽  
Rui Li ◽  
Jin Li ◽  
...  
Keyword(s):  
Older Adults ◽  
Prefrontal Cortex ◽  
Episodic Memory ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Anterior Cingulate ◽  
Controlled Study ◽  
Healthy Older Adults ◽  
Sham Stimulation ◽  
Direct Current Stimulation

Memory decline has become an issue of major importance in the aging society. Anodal transcranial direct current stimulation (atDCS) is a viable tool to counteract age-associated episodic memory deterioration. However, the underlying neural mechanisms are unclear. In this single-blind, sham-controlled study, we combined atDCS and functional magnetic resonance imaging to assess the behavioral and neural consequences of multiple-session atDCS in older adults. Forty-nine healthy older adults received either 10 sessions of anodal or sham stimulation over the left dorsolateral prefrontal cortex. Before and after stimulation, participants performed a source memory task in the MRI scanner. Compared to sham stimulation, atDCS significantly improved item memory performance. Additionally, atDCS significantly increased regional brain activity around the stimulation area in the prefrontal cortex and extended to the bilateral anterior cingulate cortex. Neural changes in the prefrontal cortex correlated with memory gains. Our findings therefore indicate that multiple-session offline atDCS may improve memory in older adults by inducing neural alterations.

scholarly journals Can Transcranial Direct Current Stimulation Enhance Functionality in Older Adults? A Systematic Review

2021 ◽  
Vol 10 (13) ◽  
pp. 2981
Author(s):  
Andrés Pino-Esteban ◽  
Álvaro Megía-García ◽  
David Martín-Caro Álvarez ◽  
Hector Beltran-Alacreu ◽  
Juan Avendaño-Coy ◽  
...  
Keyword(s):  
Systematic Review ◽  
Older Adults ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Randomized Clinical Trials ◽  
Scientific Evidence ◽  
Healthy Older Adults ◽  
Sham Stimulation ◽  
Direct Current Stimulation ◽  
Potential Benefits

Transcranial direct current stimulation (tDCS) is a non-invasive, easy to administer, well-tolerated, and safe technique capable of affecting brain excitability, both at the cortical and cerebellum levels. However, its effectiveness has not been sufficiently assessed in all population segments or clinical applications. This systematic review aimed at compiling and summarizing the currently available scientific evidence about the effect of tDCS on functionality in older adults over 60 years of age. A search of databases was conducted to find randomized clinical trials that applied tDCS versus sham stimulation in the above-mentioned population. No limits were established in terms of date of publication. A total of 237 trials were found, of which 24 met the inclusion criteria. Finally, nine studies were analyzed, including 260 healthy subjects with average age between 61.0 and 85.8 years. Seven of the nine included studies reported superior improvements in functionality variables following the application of tDCS compared to sham stimulation. Anodal tDCS applied over the motor cortex may be an effective technique for improving balance and posture control in healthy older adults. However, further high-quality randomized controlled trials are required to determine the most effective protocols and to clarify potential benefits for older adults.

scholarly journals Aging, sex and cognitive Theory of Mind: a transcranial direct current stimulation study

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Mauro Adenzato ◽  
Rosa Manenti ◽  
Elena Gobbi ◽  
Ivan Enrici ◽  
Danila Rusich ◽  
...  
Keyword(s):  
Social Cognition ◽  
Theory Of Mind ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Cognitive Abilities ◽  
Healthy Aging ◽  
Cognitive Theory ◽  
Controlled Study ◽  
Double Blind ◽  
Direct Current Stimulation

AbstractAging is accompanied by changes in cognitive abilities and a great interest is spreading among researchers about aging impact on social cognition skills, such as the Theory of Mind (ToM). Transcranial direct current stimulation (tDCS) has been used in social cognition studies founding evidence of sex-related different effects on cognitive ToM task in a young people sample. In this randomized, double-blind, sham-controlled study, we applied one active and one sham tDCS session on the medial prefrontal cortex (mPFC) during a cognitive ToM task, including both social (i.e., communicative) and nonsocial (i.e., private) intention attribution conditions, in sixty healthy aging individuals (30 males and 30 females). In half of the participants the anode was positioned over the mPFC, whereas in the other half the cathode was positioned over the mPFC. The results showed that: (i) anodal tDCS over the mPFC led to significant slower reaction times (vs. sham) for social intention attribution task only in female participants; (ii) No effects were found in both females and males during cathodal stimulation. We show for the first time sex-related differences in cognitive ToM abilities in healthy aging, extending previous findings concerning young participants.

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