Serum uric acid levels correlate with benign paroxysmal positional vertigo

2013 ◽  
Vol 21 (1) ◽  
pp. 79-85 ◽  
Author(s):  
A. Celikbilek ◽  
Z. K. Gencer ◽  
L. Saydam ◽  
G. Zararsiz ◽  
N. Tanik ◽  
...  
Keyword(s):  
Uric Acid ◽  
Serum Uric Acid ◽  
Benign Paroxysmal Positional Vertigo ◽  
Positional Vertigo ◽  
Paroxysmal Positional Vertigo

scholarly journals Low Antioxidant Status of Serum Uric Acid, Bilirubin, Albumin, and Creatinine in Patients With Benign Paroxysmal Positional Vertigo

2020 ◽  
Vol 11 ◽  
Author(s):  
Ke-Hang Xie ◽  
Ling-Ling Liu ◽  
Chu-Yin Su ◽  
Xiao-Feng Huang ◽  
Bao-Xing Wu ◽  
...  
Keyword(s):  
Uric Acid ◽  
Serum Uric Acid ◽  
Antioxidant Status ◽  
Operating Characteristic ◽  
Benign Paroxysmal Positional Vertigo ◽  
Serum Levels ◽  
Stepwise Logistic Regression ◽  
Positional Vertigo ◽  
Paroxysmal Positional Vertigo ◽  
New Onset

Objective: To investigate the roles of serum uric acid (UA), bilirubin (BIL), albumin (ALB), and creatinine (CRE) as major intravascular antioxidants, in benign paroxysmal positional vertigo (BPPV).Methods: The serum levels of UA, BIL, ALB, and CRE were retrospectively analyzed in 70 patients with new-onset idiopathic BPPV and 140 age- and sex-matched healthy controls (HCs).Results: Serum UA, BIL, ALB, and CRE levels were significantly lower in the BPPV group than the HC group. Furthermore, serum levels of BIL and ALB were significantly lower in the BPPV group when compared by sex. Multiple stepwise logistic regression revealed that a reduction in serum ALB was independently related to BPPV (odds ratio = 0.688; 95% confidence interval = 0.607– 0.780). Receiver operating characteristic analyses revealed a cut-off value of 45.15 g/L for ALB with a sensitivity of 74.29% (62.97– 83.07%) and specificity of 73.57% (65.71– 80.18%).Conclusions: Serum levels of UA, BIL, ALB, and CRE were lower in BPPV patients, indicating a lower antioxidant status. Furthermore, a reduction in serum ALB was independently associated with BPPV. These results provide insights into the possible roles of oxidative stress in the pathogenesis of BPPV.

scholarly journals THE RELATIONSHIP BETWEEN URIC ACID LEVELS AND THE OCCURRENCE OF BENIGN PAROXYSMAL POSITIONAL VERTIGO

2020 ◽  
Vol 7 (7) ◽  
pp. 35-41
Keyword(s):  
Uric Acid ◽  
Significant Relationship ◽  
Benign Paroxysmal Positional Vertigo ◽  
Patient Characteristics ◽  
Chi Square ◽  
Positional Vertigo ◽  
Gelatinous Matrix ◽  
Chi Square Test ◽  
The Relationship ◽  
Paroxysmal Positional Vertigo

Background: Benign Paroxysmal Positional Vertigo (BPPV) is associated with a fundamental condition that causes the release of large amounts of otoconia, due to deficits in the structure of the interotoconial filament matrix which implants otoconia in the gelatinous matrix. Increased uric acid levels cause an inflammatory response in the gelatinous matrix so that it can cause BPPV attacks. Objective: To determine the relationship between uric acid levels with BPPV events Research Methods: This research uses a case control design. Sampling was conducted at H. Adam Malik General Hospital Medan and RS. University of Sumatera Utara. The research sample consisted of 36 BPPV cases and 36 non BPPV cases. subject on a consecutive basis. Anamnesis and physical examination are performed to diagnose BPPV and examination of uric acid levels for hyperuricemia status. Data analysis using chi-square test Results: The majority of BPPV patient characteristics were found in women (63,9%), age range 41-50 years (36,1%), high school education level (33,3%), working as a housewife (30,6%), and Batak ethnicity (69,4%). The distribution of uric acid levels in BPPV patients was 6.59 (± 1.30) mg / dl. The distribution of hyperuricemia of BPPV patients was 58.3%. There is a significant relationship between uric acid levels with BPPV events. (p = 0.033; OR = 3.18). Conclusion: there is a significant relationship between uric acid levels with BPPV.

Clinical Implications of the Center of Balance for a Veteran with Traumatic Brain Injury

2015 ◽  
pp. 280-289
Keyword(s):  
Traumatic Brain Injury ◽  
Case Report ◽  
Brain Injury ◽  
Benign Paroxysmal Positional Vertigo ◽  
Medical Center ◽  
Treatment Plan ◽  
Successful Outcome ◽  
Model Case ◽  
Positional Vertigo ◽  
Paroxysmal Positional Vertigo

Background: It is known that traumatic brain injury (TBI), even of the mild variety, can cause diffuse multisystem neurological damage. Coordination of sensory input from the visual, vestibular and somatosensory pathways is important to obtain proper balance and stabilization in the visual environment. This coordination of systems is potentially disrupted in TBI leading to visual symptoms and complaints of dizziness and imbalance. The Center of Balance (COB) at the Northport Veterans Affairs Medical Center (VAMC) is an interprofessional clinic specifically designed for patients with such complaints. An evaluation entails examination by an optometrist, audiologist and physical therapist and is concluded with a comprehensive rehabilitative treatment plan. The clinical construct will be described and a case report will be presented to demonstrate this unique model. Case Report: A combat veteran with a history of a gunshot wound to the skull, blunt force head trauma and exposure to multiple explosions presented with complaints of difficulty reading and recent onset dizziness. After thorough evaluation in the COB, the patient was diagnosed with and treated for severe oculomotor dysfunction and benign paroxysmal positional vertigo. Conclusion: Vision therapy was able to provide a successful outcome via improvement of oculomotor efficiency and control. Physical therapy intervention was able to address the benign paroxysmal positional vertigo. The specific evaluation and management as pertains to the aforementioned diagnoses, as well as the importance of an interprofessional rehabilitative approach, will be outlined.

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