Insight into the fracture evolution behavior of pre‐flawed hollow‐cylinder granite under multi‐stage increasing‐amplitude cyclic loads: A lab‐scale testing

Author(s):  
Yu Wang ◽  
Haonan Yang ◽  
Jianqiang Han ◽  
Chun Zhu
Sensor Review ◽  
2016 ◽  
Vol 36 (1) ◽  
pp. 1-6 ◽  
Author(s):  
Robert Bogue

Purpose – This paper aims to illustrate how sensors can be fabricated by combining nanomaterials with micro-electromechanical system (MEMS) technology and to give examples of recently developed devices arising from this approach. Design/methodology/approach – Following a short introduction, this paper first identifies the benefits of MEMS technology. It then discusses the techniques for integrating carbon nanotubes with MEMS and provides examples of physical and molecular sensors produced by these methods. Combining other gas-responsive nanomaterials with MEMS is then considered and finally techniques for producing graphene on silicon devices are discussed. Brief concluding comments are drawn. Findings – This shows that many physical and molecular sensors have been developed by combining nanomaterials with MEMS technology. These have been fabricated by a diverse range of techniques which are often complex and multi-stage, but significant progress has been made and some are compatible with standard CMOS processes, yielding fully integrated nanosensors. Originality/value – This provides an insight into how two key technologies are being combined to yield families of advanced sensors.


Author(s):  
G. L. Arnulfi ◽  
P. Giannattasio ◽  
C. Giusto ◽  
A. F. Massardo ◽  
D. Micheli ◽  
...  

This paper reports an experimental investigation on centrifugal compressor surge. The compression system consists of a four-stage blower with vaned diffusers and a large plenum discharging into the atmosphere through a throttle valve. Measurements of unsteady pressure and flow rate in the plant, and of instantaneous velocity in the diffusers of the first and fourth compressor stage are performed during deep surge, at several valve settings and three different rotation speeds. Additional tests have been carried out on a different system configuration, i.e., without plenum, in order to obtain the steady-state compressor characteristics and to collect reference data on stall in surge-free conditions. In this configuration, a fully developed rotating stall was detected in the compressor diffusers, while during surge it affects only a limited part of the surge cycle. The goal of the present experimental work was to get a deeper insight into unstable operating conditions of multi-stage centrifugal compressors and to validate a theoretical model of the system instability to be used for the design of dynamic control systems.


Author(s):  
Dieter E. Bohn ◽  
Ingo Balkowski ◽  
Hongwei Ma ◽  
Christian Tu¨mmers ◽  
Michael Sell

An important goal of the development of turbine bladings is to increase the efficiency for an optimized use of energy resources. This necessitates the most possible insight into the complex flow phenomena in multi-stage turbine bladings. This paper presents a combined numerical and experimental investigation of the flow field in a 2-stage axial turbine with shrouded blades, where the axial gap between the shroud and the endwall is varied between 1mm (closed cavities) and 5 mm (opened cavities). In the experimental setup at the Institute of Steam and Gas Turbines, Aachen University, the turbine is operated at a low pressure ratio of 1.4 with an inlet pressure of 3.2 bar. The rotating speed is adjusted by a water brake, which is integrated into a swing frame running in hydrostatic bearings. The rotor power dissipates in the water brake, which enables a very accurate angular momentum determination. The mass flow is measured through a calibrated nozzle installed upstream of the turbine inlet at an accuracy of better than 1%, from which stage efficiencies can be derived. For both geometric configurations (open and closed shroud cavities), the flow field at both inlet and outlet is measured using 5-hole probes as well as temperature probes at three operating conditions. The test rig is especially designed to investigate the influence of the cavity size. Therefore, the radial gaps between shroud and casing is held near zero in order to prevent an axial flow through the cavities. The experimental results are used as boundary conditions for corresponding numerical multi-stage calculations of the 3D flow through the 2-stage turbine, using the highly accurate steady Navier-Stokes inhouse computer code, CHT-Flow. The flow field measurements and the numerical simulations give deeper insight into some of the cavity-related flow field phenomena. The measurement results as well as the simulations indicate that the stator leading edge has little influence on the inlet flow field. The flow through the shroud cavities has a significant influence on the field and therefore on the machine’s performance.


2021 ◽  
pp. 1-21
Author(s):  
Chloe M. Barnes ◽  
Abida Ghouri ◽  
Peter R. Lewis

Abstract Understanding how evolutionary agents behave in complex environments is a challenging problem. Agents can be faced with complex fitness landscapes derived from multi-stage tasks, interaction with others, and limited environmental feedback. Agents that evolve to overcome these can sometimes access greater fitness, as a result of factors such as cooperation and tool use. However, it is often difficult to explain why evolutionary agents behave in certain ways, and what specific elements of the environment or task may influence the ability of evolution to find goal-achieving behaviours; even seemingly simple environments or tasks may contain features that affect agent evolution in unexpected ways. We explore principled simplification of evolutionary agent-based models, as a possible route to aiding their explainability. Using the River Crossing Task (RCT) as a case study, we draw on analysis in the Minimal River Crossing (RC-) Task testbed, which was designed to simplify the original task while keeping its key features. Using this method, we present new analysis concerning when agents evolve to successfully complete the RCT. We demonstrate that the RC- environment can be used to understand the effect that a cost to movement has on agent evolution, and that these findings can be generalised back to the original RCT. Then, we present new insight into the use of principled simplification in understanding evolutionary agents. We find evidence that behaviour dependent on features that survive simplification, such as problem structure, are amenable to prediction; while predicting behaviour dependent on features that are typically reduced in simplification, such as scale, can be invalid.


2022 ◽  
Author(s):  
Damien Beau Wilburn ◽  
Christy L Kunkel ◽  
Richard C Feldhoff ◽  
Pamela W Feldhoff ◽  
Brian C Searle

The proteomic composition of amphibian gametes is largely a molecular mystery, particularly for Urodeles (salamanders and newts) which have few genomic-scale resources. Lungless salamanders (family Plethodontidae) include approximately two thirds of all extant salamander species and are classic models of vertebrate mating behavior. As part of an extended, multi-stage courtship ritual, male plethodontid salamanders deliver rapidly evolving protein pheromones that modify female behavior and improve male reproductive success. Despite great interest in this set of pre-mating reproductive barriers, limited characterization of plethodontid gametes has prohibited investigation of post-mating pre-zygotic barriers such as sperm-egg recognition. In this study, we performed transcriptomic analyses of testis and ovary using long-read PacBio sequencing and proteomic analyses of sperm using mass spectrometry for two evolutionary divergent plethodontid species, Plethodon shermani and Desmognathus ocoee. In both species, many of the most abundant sperm proteins were paralogs of the courtship pheromones Plethodontid Receptivity Factor (PRF), Plethodontid Modulating Factor (PMF), and Sodefrin Precursor-like Factor (SPF). Sperm-specific paralogs of PMF and SPF are likely the most abundant secreted proteins in P. shermani and D. ocoee, respectively. In contrast, sperm PRF lacks a signal peptide and may be expressed in cytoplasm. PRF pheromone genes evolved independently multiple times through repeated gene duplication of sperm PRF genes and signal peptides recovered by recombination with PMF genes. Phylogenetic analysis of courtship pheromones and their sperm paralogs support that each protein family evolved for these two reproductive contexts at distinct evolutionary time points between 17 and 360 million years ago. As the first molecular characterization of salamander gametes, this study expands our knowledge of amphibian fertilization beyond frogs and provides novel insight into the evolutionary processes by which new, rapidly evolving reproductive proteins may evolve.


2017 ◽  
Vol 5 (43) ◽  
pp. 22576-22587 ◽  
Author(s):  
Valeryia Kasneryk ◽  
Maksym Opanasenko ◽  
Mariya Shamzhy ◽  
Zuzana Musilová ◽  
Yamini S. Avadhut ◽  
...  

Investigation of the kinetics of UOV germanosilicate alumination by X-ray diffraction, 27Al and 29Si MAS NMR, ICP/OES and FTIR spectroscopy showed the multi-stage mechanism of the process.


2021 ◽  
Vol 50 (Supplement_1) ◽  
Author(s):  
Anthony Webster

Abstract Background Since Armitage and Doll's publication of “a multi-stage theory of carcinogenesis” in 1954, the multi-stage model has underpinned our conceptual understanding of cancer. In the last few years the model has been applied to other diseases, such as Amyotrophic Lateral Sclerosis (Motor Neurone Disease), providing new insight into how the disease can arise and progress. Methods The multi-stage model is simplified and generalised. The result is a simple mathematical toolkit to describe carcinogenesis or other multi-stage models of disease, with simple formulae corresponding to pictorial diagrams of the multi-stage process. Important practical issues are described regarding the fitting of data and the use of multi-stage models to interpret results. Results Relationships between established cancer models are clarified, and derivations are simplified. We provide examples and highlight pitfalls of fitting multistage models to data. It is explained how genetic markers and the multi-stage paradigm can provide new insights into mechanisms of disease. Limitations of the model are discussed in the context of recent cancer research. Conclusions A simple mathematical recipe can convert biologically-motivated models for each step in a disease’s progression, into a mathematical model. The framework provides a mathematical toolkit to study the failure of complex systems, biological or otherwise, simplifying the formulation and interpretation of multi-stage models. Key messages Multi-stage models are increasingly easy to use and understand. When combined with big data and genetic markers for stratification, they offer a new tool for epidemiological studies.


2016 ◽  
Vol 49 (2) ◽  
pp. 311-333 ◽  
Author(s):  
R. Michael McGregor ◽  
Aaron A. Moore ◽  
Laura B. Stephenson

AbstractVoting behaviour in municipal elections is understudied in Canada. Existing research is limited by the type of data (aggregate instead of individual-level) and the cases evaluated (partisan when most contests are non-partisan). The objective of this study is to contribute to this literature by using individual-level data about a non-partisan election. To do so, we use data from the Toronto Election Study, conducted during the 2014 election. Our research goals are to evaluate whether a standard approach to understanding vote choice (the multi-stage explanatory model) is applicable in a non-partisan, municipal-level contest, and to determine the correlates of vote choice in the 2014 Toronto mayoral election in particular. Our analysis reveals that, although it was a formally non-partisan contest, voters tended to view the mayoral candidates in both ideological and partisan terms. We also find that a standard vote choice model provides valuable insight into voter preferences at the municipal level.


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