scholarly journals Are high-care nursing home residents at greater risk of unplanned hospital admission than other elderly patients when exposed to Beers potentially inappropriate medications?

2013 ◽  
Vol 14 (4) ◽  
pp. 934-941 ◽  
Author(s):  
Sylvie D Price ◽  
C D'Arcy J Holman ◽  
Frank M Sanfilippo ◽  
Jon D Emery
Pharmaceutics ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 266
Author(s):  
Mathilde Bories ◽  
Guillaume Bouzillé ◽  
Marc Cuggia ◽  
Pascal Le Corre

Drug–drug interactions (DDI) occurring with potentially inappropriate medications (PIM) are additional risk factors that may increase the inappropriate character of PIM. The aim of this study was (1) to describe the prevalence and severity of DDI in patients with PIM and (2) to evaluate the DDI specifically regarding PIM. This systematic review is based on a search carried out on PubMed and Web-of-Science from inception to June 30, 2020. We extracted data of original studies that assessed the prevalence of both DDI and PIM in elderly patients in primary care, nursing home and hospital settings. Four hundred and forty unique studies were identified: 91 were included in the qualitative analysis and 66 were included in the quantitative analysis. The prevalence of PIM in primary care, nursing home and hospital were 19.1% (95% confidence intervals (CI): 15.1–23.0%), 29.7% (95% CI: 27.8–31.6%) and 44.6% (95% CI: 28.3–60.9%), respectively. Clinically significant severe risk-rated DDI averaged 28.9% (95% CI: 17.2–40.6), in a hospital setting; and were approximately 7-to-9 lower in primary care and nursing home, respectively. Surprisingly, only four of these studies investigated DDI involving specifically PIM. Hence, given the high prevalence of severe DDI in patients with PIM, further investigations should be carried out on DDI involving specifically PIM which may increase their inappropriate character, and the risk of adverse drug reactions.


2020 ◽  
pp. 016327871990065 ◽  
Author(s):  
Marko Stojanović ◽  
Milica Vuković ◽  
Milan Jovanović ◽  
Srđan Dimitrijević ◽  
Miroslav Radenković

There is currently limited information on the comparative effectiveness of the European Union(7)-potentially inappropriate medication (EU(7)-PIM) list and the Beers criteria for screening PIMs, of which PIMs are a significant concern, in the geriatric population of nursing home residents. This study aims to determine and compare the rates of PIMs detected with the Beers criteria (five sections of which the first is a list of inappropriate medications in older adults) and the EU(7)-PIM list (based on the first section of the Beers criteria). The study, conducted in Gerontology Center Belgrade ( n = 427), is retrospective and observational. The EU(7)-PIM list detected 876 PIMs, while the first section of the Beers criteria detected 782 PIMs (1,803 with all five sections). The majority of PIMs belong to psychotropic drugs (benzodiazepines being the most common). The EU(7)-PIM list detected significantly more PIMs than the first section of the Beers criteria (2.03 ± 1.63 vs. 1.83 ± 1.27; p = .0005). The number of detected PIMs with both criteria correlates with age, the number of chronic illnesses, the number of medication prescribed, and the comorbidity status. Ultimately, the EU(7)-PIM list detected more PIMs compared to the first section of the Beers criterion.


2016 ◽  
Vol 38 (5) ◽  
pp. 1103-1111 ◽  
Author(s):  
Filipa Alves da Costa ◽  
Catarina Periquito ◽  
Maria Clara Carneiro ◽  
Pedro Oliveira ◽  
Ana Isabel Fernandes ◽  
...  

Pharmacy ◽  
2019 ◽  
Vol 7 (1) ◽  
pp. 26 ◽  
Author(s):  
Kjell Halvorsen ◽  
Sinan Kucukcelik ◽  
Beate Garcia ◽  
Kristian Svendsen

Background: Nursing home residents often have several conditions that necessitate the use of multiple medicines. This study investigates the prevalence of potentially inappropriate medications (PIMs) and its associations with sex, age, number of medicines, and study location (rural/urban). Methods: A cross-sectional study of long-term care residents from six nursing homes. Data was collected from medical records. We identified PIMs by applying the NORGEP-NH criteria. We conducted a Poisson regression analysis to investigate the association between the number of PIMs and sex, age, number of medicines, and study location. Results: We included 103 (18.4%) of 559 residents (68.0% women; mean age 83.2 years, mean number of daily used medicines 7.2 (SD = 3.6)). We identified PIMs in 56% of the residents (mean number = 1.10, SD = 1.26). In adjusted analyses, residents ≥80 years had 0.43 fewer PIMs compared to residents <80 years (p < 0.05). Residents using 4–6, 7–9, and 10+ medicines had on average 0.73, 1.06, and 2.11 more PIMs compared to residents using 0–3 medicines (p < 0.001), respectively. Conclusion: PIM use is prevalent among nursing home residents and is significantly associated with age and number of medicines. Our findings suggest a modest decrease in residents using PIMs compared to previous studies. Nevertheless, prescribing quality in nursing home residents in both urban and rural areas is still of great concern.


Drugs & Aging ◽  
2020 ◽  
Vol 37 (12) ◽  
pp. 917-924
Author(s):  
Anne Fournier ◽  
Pauline Anrys ◽  
Jean-Baptiste Beuscart ◽  
Olivia Dalleur ◽  
Séverine Henrard ◽  
...  

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