A mild hand cleanser, alkyl ether sulphate supplemented with alkyl ether carboxylic acid and alkyl glucoside, improves eczema on the hand and prevents the growth ofStaphylococcus aureuson the skin surface

2016 ◽  
Vol 38 (6) ◽  
pp. 599-606 ◽  
Author(s):  
S. Fukui ◽  
T. Morikawa ◽  
M. Hirahara ◽  
Y. Terada ◽  
M. Shimizu ◽  
...  
Keyword(s):  
Carboxylic Acid ◽  
Skin Surface ◽  
Alkyl Ether ◽  
Alkyl Glucoside

Enzymatic Determination of Hydroxysteroids in Human Skin Surface Lipids1

1963 ◽  
Vol 41 (5) ◽  
pp. 265-268 ◽  
Author(s):  
Thomas J Cook ◽  
Allan L Lorincz ◽  
Alan R Spector
Keyword(s):  
Human Skin ◽  
Skin Surface ◽  
Enzymatic Determination

Fibrinolytic Activity of Cerebro-Spinal Fluid and the Development of Artificial Cerebral Haematomas in Dogs

1969 ◽  
Vol 21 (02) ◽  
pp. 294-303 ◽  
Author(s):  
H Mihara ◽  
T Fujii ◽  
S Okamoto
Keyword(s):  
Cerebrospinal Fluid ◽  
Carboxylic Acid ◽  
Fibrinolytic Activity ◽  
Clinical Implications ◽  
Trans Form ◽  
Plate Method ◽  
Blood Samples ◽  
Fibrin Plate ◽  
The Brain

SummaryBlood was injected into the brains of dogs to produce artificial haematomas, and paraffin injected to produce intracerebral paraffin masses. Cerebrospinal fluid (CSF) and peripheral blood samples were withdrawn at regular intervals and their fibrinolytic activities estimated by the fibrin plate method. Trans-form aminomethylcyclohexane-carboxylic acid (t-AMCHA) was administered to some individuals. Genera] relationships were found between changes in CSF fibrinolytic activity, area of tissue damage and survival time. t-AMCHA was clearly beneficial to those animals given a programme of administration. Tissue activator was extracted from the brain tissue after death or sacrifice for haematoma examination. The possible role of tissue activator in relation to haematoma development, and clinical implications of the results, are discussed.

Validation and inter-rater reliability of inexpensive, mini, no-touch infrared surface thermometry devices as an assessment tool for prediction of wound-related deep and surrounding infection

WCET Journal ◽  
2019 ◽  
pp. 18-22
Author(s):  
Hiske Smart ◽  
Eman Al Al Jahmi ◽  
Ebrahim Buhiji ◽  
Sally-Anne Smart
Keyword(s):  
Temperature Difference ◽  
Assessment Tool ◽  
Predictive Ability ◽  
Skin Surface ◽  
Infrared Thermometry ◽  
Health Care Clinics ◽  
Primary Health ◽  
Wound Assessment ◽  
The Times ◽  
Assessment Modality

Industrial infrared thermometry devices are large and, despite being less expensive than the current gold standard Exergen Dermatemp medical infrared thermometer, are still not affordable enough to ensure unrestricted and consistent use of this assessment modality in regular wound-related day-to-day practice. An increased skin surface temperature differentiation of 3°F associated with a wound has a positive predictive ability to detect deep or surrounding wound infection. This study hypothesised that inexpensive, pen- or pocket-sized, no-touch surface infrared thermometry devices will be equal in ability to detect a 3oF increased skin temperature compared to the Exergen Dermatemp infrared device and be reliable in the hands of any wound assessor. The odds of the control and other thermometers to detect a 3oF temperature difference, irrespective of the raters, were achieved in all five of the mini thermometers tested, with a correct temperature difference prediction that occurred in 90.933% of the times (odds determined 9/10). As a result of this study mini, no-touch infrared thermometry, to detect a 3oF temperature difference in wound assessment to determine tendency, could be implemented into primary health care clinics, rural clinics, day-to-day hospital practice and standard outpatients departments at a small financial cost, regardless of which thermometer is put to use.

Analysis of Skin Surface Lipids

1975 ◽  
Vol 37 (6) ◽  
pp. 909-917 ◽  
Author(s):  
Tokuji HIROWATARI
Keyword(s):  
Skin Surface ◽  
Surface Lipids ◽  
Skin Surface Lipids

The Possible Function of sIgA on the Skin Surface in Vivo.

1995 ◽  
Vol 57 (1) ◽  
pp. 52-54 ◽  
Author(s):  
Takako GOTO ◽  
Takahiro GYOTOKU ◽  
Shuhei IMAYAMA ◽  
Yoshiaki HORI
Keyword(s):  
Skin Surface

Stereospecific, Palladium-catalyzed C(sp3)–H Alkenylation and Alkynylation of a Proline Derivative Enabled by 8-Aminoquinoline as a Directing Group

2020 ◽  
Author(s):  
Aleksandra Balliu ◽  
Aaltje Roelofje Femmigje Strijker ◽  
Michael Oschmann ◽  
Monireh Pourghasemi Lati ◽  
Oscar Verho
Keyword(s):  
Carboxylic Acid ◽  
Building Blocks ◽  
Wide Range ◽  
Palladium Catalyzed ◽  
Directing Group ◽  
High Yields ◽  
Vinyl Iodides ◽  
Initial Results

<p>In this preprint, we present our initial results concerning a stereospecific Pd-catalyzed protocol for the C3 alkenylation and alkynylation of a proline derivative carrying the well utilized 8‑aminoquinoline directing group. Efficient C–H alkenylation was achieved with a wide range of vinyl iodides bearing different aliphatic, aromatic and heteroaromatic substituents, to furnish the corresponding C3 alkenylated products in good to high yields. In addition, we were able show that this protocol can also be used to install an alkynyl group into the pyrrolidine scaffold, when a TIPS-protected alkynyl bromide was used as the reaction partner. Furthermore, two different methods for the removal of the 8-aminoquinoline auxiliary are reported, which can enable access to both <i>cis</i>- and <i>trans</i>-configured carboxylic acid building blocks from the C–H alkenylation products.</p>

Ketones from Nickel-Catalyzed Decarboxylative, Non-Symmetric Cross-Electrophile Coupling of Carboxylic Acid Esters

2019 ◽  
Author(s):  
Jiang Wang ◽  
Brian P. Cary ◽  
Peyton Beyer ◽  
Samuel H. Gellman ◽  
Daniel Weix
Keyword(s):  
Carboxylic Acid ◽  
Solid Support ◽  
Reaction Conditions ◽  
Decarboxylative Coupling ◽  
New Strategy ◽  
The Cross ◽  
Acyl Donors ◽  
Acid Esters

A new strategy for the synthesis of ketones is presented based upon the decarboxylative coupling of N-hydroxyphthalimide (NHP) esters with S-2-pyridyl thioesters. The reactions are selective for the cross-coupled product because NHP esters act as radical donors and the thioesters act as acyl donors. The reaction conditions are general and mild, with over 40 examples presented, including larger fragments and the 20-mer peptide Exendin(9-39) on solid support.

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