Stratification by obesity class, rather than age, can identify a higher percent of children at risk for non‐alcoholic fatty liver disease and metabolic dysfunction

2021 ◽  
Author(s):  
Aurelia Radulescu ◽  
Adam J. Dugan ◽  
Mary Killian ◽  
Suzanna L. Attia ◽  
Marialena Mouzaki ◽  
...  
2021 ◽  
Vol 4 (2) ◽  
pp. 99-102
Author(s):  
Hiroshi Bando

The problems among obesity, diabetes mellitus (DM), fatty liver, metabolic dysfunction have been prevalent, and diagnostic criteria as non-alcoholic fatty liver disease (NAFLD) has been used in practice. When diagnosing NAFLD, to exclude other related liver diseases was necessary, including excessive alcohol intake. The international experts proposed the proper term from NAFLD to metabolic associated fatty liver disease (MAFLD). MAFLD criteria include the evidence of the presence of hepatic steatosis associated with three situations. They are obesity/overweight, presence of Type 2 DM (T2DM), or metabolic impaired function, which were studied in the light of pathophysiology, epidemiology, diagnosis and pharmacotherapy.


2021 ◽  
pp. 1-3
Author(s):  
Elizondo Martín ◽  
◽  
Rey Romina and Gerona Solange ◽  

Introduction: Non-alcoholic fatty liver disease affects 1/3 to ¼ of the world’s population. Currently this pathology is being redefined by using the acronym MALFD (Metabolic Dysfunction-Associated Fatty Liver Disease) and the possibility of new criteria for its diagnosis is being discussed. Methodology: Prospective and descriptive studies carried out between July 2018 and June 2020 where the applicability of the new criteria in MAFLD diagnosis were valued. Patients with NAFLD (Non-alcoholic fatty liver disease) were enrolled in clinics specialized in this pathology. Results: Out of 172 patients enrolled, 96.4% (this represents a total of 165 patients) presented obesity, were over weighted and or presented Diabetes Mellitus. The rest of the patients (a total of 7) presented high blood pressure and or dyslipidemia. Moreover, it was observed that the higher the obesity index the higher the prevalence of Diabetes Mellitus. Conclusions: The criteria for the diagnosis of MAFLD are adaptable in patients with a diagnosis of NAFLD from the first consultation and allow the assessment of prognostic elements of the disease. This would allow us to intervene at very early stages which could impact patient’s prognosis


2018 ◽  
Vol 38 (10) ◽  
pp. 1832-1838 ◽  
Author(s):  
Jane I. Grove ◽  
Prarthana Thiagarajan ◽  
Stuart Astbury ◽  
Rebecca Harris ◽  
Toby Delahooke ◽  
...  

2016 ◽  
Vol 233 (23-24) ◽  
pp. 3947-3952 ◽  
Author(s):  
María José Morlán-Coarasa ◽  
María Teresa Arias-Loste ◽  
Víctor Ortiz-García de la Foz ◽  
Obdulia Martínez-García ◽  
Carmen Alonso-Martín ◽  
...  

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