Congenital Ichthyosiform Erythroderma: Particulate Staining Pattern of TGK

1999 ◽  
Vol 26 (12) ◽  
pp. 791-796
Author(s):  
Ken Hashimoto ◽  
Kazuaki Tanaka ◽  
Indira Misra ◽  
Tor Shwayder ◽  
Ali Moiin
Keyword(s):  
Staining Pattern ◽  
Congenital Ichthyosiform Erythroderma

The staining pattern of the tropomyosin sequence is displayed in a new paracrystal

1986 ◽  
Vol 44 ◽  
pp. 150-151
Author(s):  
M.K. Lamvik ◽  
L.L. Klatt
Keyword(s):  
Amino Acid ◽  
Amino Acid Sequence ◽  
Staining Pattern ◽  
Banding Patterns ◽  
Mass Thickness ◽  
New Form

Tropomyosin paracrystals have been used extensively as test specimens and magnification standards due to their clear periodic banding patterns. The paracrystal type discovered by Ohtsuki1 has been of particular interest as a test of unstained specimens because of alternating bands that differ by 50% in mass thickness. While producing specimens of this type, we came across a new paracrystal form. Since this new form displays aligned tropomyosin molecules without the overlaps that are characteristic of the Ohtsuki-type paracrystal, it presents a staining pattern that corresponds to the amino acid sequence of the molecule.

scholarly journals COMPARATIVE STUDIES OF LIGHT MEROMYOSIN PARACRYSTALS DERIVED FROM RED, WHITE, AND CARDIAC MUSCLE MYOSINS

1971 ◽  
Vol 49 (3) ◽  
pp. 883-898 ◽  
Author(s):  
A. Nakamura ◽  
F. Sreter ◽  
J. Gergely
Keyword(s):  
Molecular Structure ◽  
Cardiac Muscle ◽  
Functional Properties ◽  
Comparative Studies ◽  
White Muscle ◽  
Staining Pattern ◽  
Uranyl Acetate ◽  
Positive Staining ◽  
Cardiac Muscles

Tryptic and chymotryptic light meromyosin paracrystals from red and cardiac muscles of rabbit show a negative and positive staining pattern with uranyl acetate and phosphotungstate that sharply differs from that of white muscle light meromyosin paracrystals. The main periodicity of about 430 A is the same regardless of the source of light meromyosin. The results are discussed in terms of the molecular structure and the functional properties of various myosins.

scholarly journals The staining pattern of collagen fibrils. Improved correlation with sequence data.

1979 ◽  
Vol 254 (21) ◽  
pp. 10710-10714
Author(s):  
K.M. Meek ◽  
J.A. Chapman ◽  
R.A. Hardcastle
Keyword(s):  
Sequence Data ◽  
Staining Pattern ◽  
Collagen Fibrils

scholarly journals Sinonasal FUS-ERG-Rearranged Ewing’s Sarcoma Mimicking Glomangiopericytoma

2020 ◽  
Vol 13 (3) ◽  
pp. 1393-1396
Author(s):  
Maggie Zhou ◽  
Yen Chen Kevin Ko ◽  
Gregory W. Charville ◽  
Kristen N. Ganjoo
Keyword(s):  
Ewing’S Sarcoma ◽  
Ewing's Sarcoma ◽  
Staining Pattern ◽  
Gene Arrangement ◽  
Round Cell ◽  
The Family ◽  
History Of ◽  
Blue Cell ◽  
Aggressive Tumor ◽  
Membranous Staining

Ewing’s sarcoma is a rare and aggressive tumor that typically arises in the long bones of the extremities. It belongs in the family of small round blue cell tumors and is characterized immunohistochemically by diffuse CD99 expression and molecularly by one of several oncogenic translocations, most commonly t(11;22)(q24;q12) between the <i>EWSR1</i> gene and the <i>FLI1</i> gene. Here we present a rare case of Ewing’s sarcoma in the sinonasal tract with <i>FUS-ERG</i> gene arrangement that was regarded for almost a decade as a sinonasal-type hemangiopericytoma (glomangiopericytoma). This case illustrates the surprisingly prolonged natural history of Ewing’s sarcoma that did not receive therapy for many years and the importance of considering alternative genetic translocations. Our experience suggests that the presence of diffuse CD99 membranous staining pattern in a small blue round cell tumor with morphology typical for Ewing’s sarcoma but FISH negative for <i>EWSR1</i> rearrangement should prompt consideration of <i>FUS-ERG</i> fusion.

Development of multiple non-melanoma skin carcinomas in a patient with non-bullous congenital ichthyosiform erythroderma

2010 ◽  
Vol 38 (8) ◽  
pp. 813-816 ◽  
Author(s):  
Şirin YAŞAR ◽  
Ayşe Tülin MANSUR ◽  
İkbal Esen AYDINGŎZ ◽  
Fatih GŎKTAY ◽  
Gamze Erfan TÜRKER ◽  
...  
Keyword(s):  
Congenital Ichthyosiform Erythroderma ◽  
Melanoma Skin

Structure, function, and expression of SEL-1, a negative regulator of LIN-12 and GLP-1 in C. elegans

Development ◽  
1997 ◽  
Vol 124 (3) ◽  
pp. 637-644 ◽  
Author(s):  
B. Grant ◽  
I. Greenwald
Keyword(s):  
Staining Pattern ◽  
Signal Sequence ◽  
Negative Regulator ◽  
Yeast Gene ◽  
Hydrophobic Region ◽  
C Elegans ◽  
Cell Ablation ◽  
New Information ◽  
Membrane Bound ◽  
Punctate Staining

Previous work indicated that sel-1 functions as a negative regulator of lin-12 activity, and predicted that SEL-1 is a secreted or membrane associated protein. In this study, we describe cell ablation experiments that suggest sel-1 mutations elevate lin-12 activity cell autonomously. We also use transgenic approaches to demonstrate that the predicted signal sequence of SEL-1 can direct secretion and is important for function, while a C-terminal hydrophobic region is not required for SEL-1 function. In addition, by analyzing SEL-1 localization using specific antisera we find that SEL-1 is localized intracellularly, with a punctate staining pattern suggestive of membrane bound vesicles. We incorporate these observations, and new information about a related yeast gene, into a proposal for a possible mechanism for SEL-1 function in LIN-12 turnover.

scholarly journals ABCA12-deficient Congenital Ichthyosiform Erythroderma in a Boy with an Intellectual Developmental Delay

2015 ◽  
Vol 95 (6) ◽  
pp. 747-749 ◽  
Author(s):  
Y Inoue ◽  
M Yamamoto ◽  
Y Sakaguchi ◽  
O Jitsukawa ◽  
K Hayano ◽  
...  
Keyword(s):  
Developmental Delay ◽  
Congenital Ichthyosiform Erythroderma
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