scholarly journals The tomato UV-damaged DNA-binding protein-1 (DDB1) is implicated in pathogenesis-related (PR) gene expression and resistance to Agrobacterium tumefaciens

2011 ◽  
Vol 13 (2) ◽  
pp. 123-134 ◽  
Author(s):  
JIKAI LIU ◽  
HANJING LI ◽  
MIN MIAO ◽  
XIAOFENG TANG ◽  
JIM GIOVANNONI ◽  
...  
Keyword(s):  
Gene Expression ◽  
Agrobacterium Tumefaciens ◽  
Dna Binding ◽  
Binding Protein ◽  
Dna Binding Protein ◽  
Pathogenesis Related ◽  
Pr Gene Expression ◽  
Damaged Dna

scholarly journals A novel DNA-binding protein regulates sexual differentiation in malaria parasites and is essential for transmission

2020 ◽  
Author(s):  
Riward Campelo Morillo ◽  
Xinran Tong ◽  
Wei Xie ◽  
Todd Lenz ◽  
Gayani Batugedara ◽  
...  
Keyword(s):  
Gene Expression ◽  
Dna Binding ◽  
Sexual Differentiation ◽  
Binding Protein ◽  
Dna Binding Protein ◽  
Homeodomain Protein ◽  
Mosquito Vector ◽  
Malaria Parasites ◽  
Membrane Complex ◽  
Inner Membrane Complex

ABSTRACTTransmission of Plasmodium falciparum and other malaria parasites requires their differentiation from asexual blood stages into gametocytes, the non-replicative sexual stage necessary for transmission to the mosquito vector. This transition involves changes in gene expression and chromatin reorganization mediating the silencing and activation of stage-specific genes. However, malaria parasites have been noted for their dearth of transcriptional and chromatin regulators and the molecular mediators of these changes remain largely unknown. We identified Homeodomain protein 1 (HDP1) as a novel chromatin-associated DNA-binding protein that drives changes in chromatin structure and gene expression during early sexual differentiation. This discovery of a homeodomain-like DNA-binding protein marks a new class of transcriptional regulator in malaria parasites outside of the better-characterized ApiAP2 family. In this study, we demonstrate that HDP1 is required for gametocyte maturation and parasite transmission by driving the necessary upregulation of inner membrane complex components in early gametocytes.

scholarly journals Gene D5 product of bacteriophage T5: DNA-binding protein affecting DNA replication and late gene expression.

1979 ◽  
Vol 29 (1) ◽  
pp. 322-327 ◽  
Author(s):  
D J McCorquodale ◽  
J Gossling ◽  
R Benzinger ◽  
R Chesney ◽  
L Lawhorne ◽  
...  
Keyword(s):  
Gene Expression ◽  
Dna Replication ◽  
Dna Binding ◽  
Binding Protein ◽  
Dna Binding Protein ◽  
Late Gene ◽  
Late Gene Expression ◽  
Bacteriophage T5

scholarly journals Damaged DNA Binding Protein 2 Plays a Role in Breast Cancer Cell Growth

PLoS ONE ◽  
2008 ◽  
Vol 3 (4) ◽  
pp. e2002 ◽  
Author(s):  
Zilal Kattan ◽  
Sophie Marchal ◽  
Emilie Brunner ◽  
Carole Ramacci ◽  
Agnès Leroux ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Growth ◽  
Dna Binding ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Binding Protein ◽  
Dna Binding Protein ◽  
Cancer Cell Growth ◽  
Breast Cancer Cell Growth ◽  
Damaged Dna
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