scholarly journals Short-term survival and long-term mortality ofAcacia drepanolobiumafter a controlled burn

2008 ◽  
Vol 46 (3) ◽  
pp. 395-401 ◽  
Author(s):  
B. D. Okello ◽  
T. P. Young ◽  
C. Riginos ◽  
D. Kelly ◽  
T. G. O’Connor
Keyword(s):  
Short Term ◽  
Term Survival ◽  
Controlled Burn ◽  
Long Term Mortality ◽  
Short Term Survival

scholarly journals Parenteral Nutrition and Oxidant Load in Neonates

Nutrients ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 2631
Author(s):  
Kandeepan Karthigesu ◽  
Robert F. Bertolo ◽  
Robert J. Brown
Keyword(s):  
Parenteral Nutrition ◽  
Storage Temperature ◽  
Oral Feeding ◽  
Published Data ◽  
Short Term ◽  
Antioxidant Defences ◽  
Term Survival ◽  
Nutrient Sources ◽  
Short Term Survival

Neonates with preterm, gastrointestinal dysfunction and very low birth weights are often intolerant to oral feeding. In such infants, the provision of nutrients via parenteral nutrition (PN) becomes necessary for short-term survival, as well as long-term health. However, the elemental nutrients in PN can be a major source of oxidants due to interactions between nutrients, imbalances of anti- and pro-oxidants, and environmental conditions. Moreover, neonates fed PN are at greater risk of oxidative stress, not only from dietary sources, but also because of immature antioxidant defences. Various interventions can lower the oxidant load in PN, including the supplementation of PN with antioxidant vitamins, glutathione, additional arginine and additional cysteine; reduced levels of pro-oxidant nutrients such as iron; protection from light and oxygen; and proper storage temperature. This narrative review of published data provides insight to oxidant molecules generated in PN, nutrient sources of oxidants, and measures to minimize oxidant levels.

Physicians’ predictions of long-term survival and functional outcomes do not influence the decision to admit patients with advanced disease to intensive care: A prospective study

2020 ◽  
pp. 026921632096393
Author(s):  
Monica Escher ◽  
Mathieu Nendaz ◽  
Fabienne Scherer ◽  
Stéphane Cullati ◽  
Thomas Perneger
Keyword(s):  
Intensive Care ◽  
Functional Outcomes ◽  
Advanced Disease ◽  
Short Term ◽  
Term Survival ◽  
Admission Decisions ◽  
Long Term Prognosis ◽  
A Prospective Study ◽  
Short Term Survival

Background: Long-term survival and functional outcomes should influence admission decisions to intensive care, especially for patients with advanced disease. Aim: To determine whether physicians’ predictions of long-term prognosis influenced admission decisions for patients with and without advanced disease. Design: A prospective study was conducted. Physicians estimated patient survival with intensive care and with care on the ward, and the probability of 4 long-term outcomes: leaving hospital alive, survival at 6 months, recovery of functional status, and recovery of cognitive status. Patient mortality at 28 days was recorded. We built multivariate logistic regression models using admission to the intensive care unit (ICU) as the dependent variable. Setting/participants: ICU consultations for medical inpatients at a Swiss tertiary care hospital were included. Results: Of 201 evaluated patients, 105 (52.2%) had an advanced disease and 140 (69.7%) were admitted to the ICU. The probability of admission was strongly associated with the expected short-term survival benefit for patients with or without advanced disease. In contrast, the predicted likelihood that the patient would leave the hospital alive, would be alive 6 months later, would recover functional status, and would recover initial cognitive capacity was not associated with the decision to admit a patient to the ICU. Even for patients with advanced disease, none of these estimated outcomes influenced the admission decision. Conclusions: ICU admissions of patients with advanced disease were determined by short-term survival benefit, and not by long-term prognosis. Advance care planning and developing decision-aid tools for triage could help limit potentially inappropriate admissions to intensive care.

Abstract 1279: Proteomics signature of long-term versus short-term survival in glioblastoma

2012 ◽  
Author(s):  
Jill Barnholtz-Sloan ◽  
Giridharan Gokulrangan ◽  
Yanwen Chen ◽  
Elizabeth Yohannes ◽  
Jaime Vengoechea ◽  
...  
Keyword(s):  
Short Term ◽  
Term Survival ◽  
Short Term Survival

scholarly journals Correlation between neutrophil-to-lymphocyte ratio and postoperative mortality in elderly patients with hip fracture: a meta-analysis

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Yu-Hang Chen ◽  
Ching-Hsin Chou ◽  
Hsin-Hsien Su ◽  
Yu-Ting Tsai ◽  
Ming-Hsiu Chiang ◽  
...  
Keyword(s):  
Hip Fracture ◽  
Elderly Patients ◽  
Geriatric Patients ◽  
Meta Analysis ◽  
Postoperative Mortality ◽  
Short Term ◽  
Term Survival ◽  
Lymphocyte Ratio ◽  
Long Term Mortality

Abstract Introduction The neutrophil-to-lymphocyte ratio (NLR) is a crucial prognosis predictor following several major operations. However, the association between NLR and the outcome after hip fracture surgery is unclear. In this meta-analysis, we investigated the correlation between NLR and postoperative mortality in geriatric patients following hip surgery. Method PubMed, Embase, Cochrane library, and Google Scholar were searched for studies up to June 2021 reporting the correlation between NLR and postoperative mortality in elderly patients undergoing surgery for hip fracture. Data from studies reporting the mean of NLR and its 95% confidence interval (CI) were pooled. Both long-term (≥ 1 year) and short-term (≤ 30 days) mortality rates were included for analysis. Result Eight retrospective studies comprising a total of 1563 patients were included. Both preoperative and postoperative NLRs (mean difference [MD]: 2.75, 95% CI: 0.23–5.27; P = 0.03 and MD: 2.36, 95% CI: 0.51–4.21; P = 0.01, respectively) were significantly higher in the long-term mortality group than in the long-term survival group. However, no significant differences in NLR were noted between the short-term mortality and survival groups (MD: − 1.02, 95% CI: − 3.98 to 1.93; P = 0.5). Conclusion Higher preoperative and postoperative NLRs were correlated with a higher risk of long-term mortality following surgery for hip fracture in the geriatric population, suggesting the prognostic value of NLR for long-term survival. Further studies with well-controlled confounders are warranted to clarify the predictive value of NLR in clinical practice in geriatric patients with hip fracture.

scholarly journals SHORT- AND LONG-TERM OUTCOMES OF A SECOND ARTERIAL CONDUIT FOLLOWING CORONARY BYPASS GRAFTING

2021 ◽  
Author(s):  
Sleiman Sebastian Aboul-Hassan ◽  
Jakub Marczak ◽  
Tomasz Stankowski ◽  
Lukasz Moskal ◽  
Maciej Peksa ◽  
...  
Keyword(s):  
Internal Thoracic Artery ◽  
Deep Sternal Wound Infection ◽  
Bypass Grafting ◽  
Short Term ◽  
Term Survival ◽  
Long Term Outcome ◽  
Long Term Survival ◽  
Arterial Conduit ◽  
Long Term Mortality

Background: The aim of this study was to assess the effect on short-term outcomes and long-term survival in patients following coronary artery bypass grafting in whom second arterial conduit(right internal thoracic artery-RITA or radial artery-RA) or saphenous vein was grafted and between RITA and RA as second best arterial conduit. Methods: Between January-2006 and June-2018, 7857-patients met the inclusion criteria and were divided into two groups: single internal thoracic artery: SITA+Vein group(n=7140) and 2nd-arterial conduit group(n=717), of these 537-patients received RITA and 180-patients received RA. Short‐term outcomes included: 30-day mortality and Major Adverse Cardiac and Cerebral Events(MACCE), reoperation for bleeding and deep sternal wound infection(DSWI). The long‐term outcome was all‐cause mortality. propensity score(PS) matching was used to match patients between the groups. Results: Before as well as after PS-matching, no significant differences were observed between 2nd-arterial conduit vs SITA+Vein groups and between RITA vs RA groups in terms of 30-day mortality, 30-day MACCE, reoperation for bleeding and incidence of DSWI. The use of 2nd-arterial conduit was associated with a significant reduction in long-term mortality before(HR:0.52;95%CI;0.43-0.64;p<0.001) as well as after PS-matching(HR:0.77;95%CI;0.60-0.99;p=0.04). RA and RITA as second arterial conduit had comparable long-term mortality before(HR:1.22;95%CI;0.82-1.82;p=0.3) as well as after PS-matching(HR:0.96;95%CI;0.58-1.58;p=0.87). Conclusions: The use of 2nd-arterial conduit vs vein is associated with improved long-term survival. As for the 2nd-best arterial conduit, RA and RITA had comparable long-term mortality.

scholarly journals On-Side fighting in civil war: The logic of mortal alignment in Syria

2020 ◽  
Vol 32 (4) ◽  
pp. 402-460
Author(s):  
Jonah Schulhofer-Wohl
Keyword(s):  
Civil Wars ◽  
Political Competition ◽  
Spatial And Temporal Variation ◽  
Armed Groups ◽  
Short Term ◽  
Term Survival ◽  
Fine Grained ◽  
Trade Offs ◽  
Short Term Survival

On-side fighting – outright violence between armed groups aligned on the same side of a civil war’s master cleavage – represents a devastating breakdown in cooperation. Its humanitarian consequences are also grave. But it has been under-recognized empirically and therefore under-theorized by scholars to date. This article remedies the omission. Existing research can be extrapolated to produce candidate explanations, but these overlook spatial and temporal variation in on-side fighting within a war. I provide a theory that accounts for this ebb and flow. On-side fighting hinges on belligerents’ trade-offs between short-term survival and long-term political objectives. Enemy threats to survival underpin on-side cooperation; in their absence, belligerents can pursue political gains against on-side competitors. I evaluate this threat-absence theory using evidence from the ongoing Syrian Civil War’s first years. Fine-grained fatalities data capture fluctuating enemy threats to on-side groups’ survival and situate on-side fighting and its absence. Findings support threat-absence theory and contribute to research on warfighting and political competition in civil wars and to the study of coalition dynamics in other settings, including elections and legislatures.

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