Red blood cell aggregability in patients with a history of leg vein thrombosis: influence of post-thrombotic treatment

1994 ◽  
Vol 88 (1) ◽  
pp. 174-179 ◽  
Author(s):  
Anne Chabanel ◽  
Marie Hélé;ne Horellou ◽  
Jacqueline Conard ◽  
Meyer M. Samama
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Vein Thrombosis ◽  
History Of

scholarly journals Red Blood Cell Transfusion in the Emergency Department: An Observational Cross-Sectional Multicenter Study

2021 ◽  
Vol 10 (11) ◽  
pp. 2475
Author(s):  
Olivier Peyrony ◽  
Danaé Gamelon ◽  
Romain Brune ◽  
Anthony Chauvin ◽  
Daniel Aiham Ghazali ◽  
...  
Keyword(s):  
Emergency Department ◽  
Logistic Regression ◽  
Blood Cell ◽  
Red Blood Cell ◽  
Cross Sectional Study ◽  
Red Blood Cell Transfusion ◽  
Cross Sectional ◽  
Acute Bleeding ◽  
History Of ◽  
Rbc Transfusion

Background: We aimed to describe red blood cell (RBC) transfusions in the emergency department (ED) with a particular focus on the hemoglobin (Hb) level thresholds that are used in this setting. Methods: This was a cross-sectional study of 12 EDs including all adult patients that received RBC transfusion in January and February 2018. Descriptive statistics were reported. Logistic regression was performed to assess variables that were independently associated with a pre-transfusion Hb level ≥ 8 g/dL. Results: During the study period, 529 patients received RBC transfusion. The median age was 74 (59–85) years. The patients had a history of cancer or hematological disease in 185 (35.2%) cases. Acute bleeding was observed in the ED for 242 (44.7%) patients, among which 145 (59.9%) were gastrointestinal. Anemia was chronic in 191 (40.2%) cases, mostly due to vitamin or iron deficiency or to malignancy with transfusion support. Pre-transfusion Hb level was 6.9 (6.0–7.8) g/dL. The transfusion motive was not notified in the medical chart in 206 (38.9%) cases. In the multivariable logistic regression, variables that were associated with a higher pre-transfusion Hb level (≥8 g/dL) were a history of coronary artery disease (OR: 2.09; 95% CI: 1.29–3.41), the presence of acute bleeding (OR: 2.44; 95% CI: 1.53–3.94), and older age (OR: 1.02/year; 95% CI: 1.01–1.04). Conclusion: RBC transfusion in the ED was an everyday concern and involved patients with heterogeneous medical situations and severity. Pre-transfusion Hb level was rather restrictive. Almost half of transfusions were provided because of acute bleeding which was associated with a higher Hb threshold.

Red blood cell Na content, Na, Li-countertransport, family history of hypertension and blood pressure in school children

1988 ◽  
Vol 6 (3) ◽  
pp. 227-230 ◽  
Author(s):  
Maurizio Trevisan ◽  
Pasquale Strazzullo ◽  
Francesco Paolo Cappuccio ◽  
Michele Roberto Di Muro ◽  
Stefano De Colle ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Family History ◽  
Blood Cell ◽  
School Children ◽  
Red Blood Cell ◽  
History Of ◽  
Family History Of Hypertension

Limiting the Extent of a Delayed Hemolytic Transfusion Reaction With Automated Red Blood Cell Exchange

2013 ◽  
Vol 137 (6) ◽  
pp. 861-864 ◽  
Author(s):  
Christopher A. Tormey ◽  
Gary Stack
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Positive Antibody ◽  
Antiglobulin Test ◽  
Hemolytic Transfusion Reaction ◽  
History Of ◽  
Delayed Hemolytic Transfusion Reaction ◽  
Antibody Screen ◽  
Patient’S History ◽  
Transfusion Reactions

Delayed hemolytic transfusion reactions (DHTRs) are mediated by blood group antibodies that undergo anamnestic increases following antigen reexposure. Available options for the treatment or prophylaxis of DHTRs are limited. We report the use of automated red blood cell exchange (ARE) to limit hemolysis associated with an emerging DHTR. Following transfusion of 12 red blood cell units, a family member's comments led to the discovery of a patient's history of 4 alloantibodies (anti-E, anti-c, anti-Fya, and anti-M). Testing revealed that all 12 units were incompatible for at least 1 antigen. Six days after transfusion, the patient developed a newly positive antibody screen and direct antiglobulin test (DAT) result. To prevent further hemolysis, ARE was performed to replace incompatible red blood cells with antigen-negative units. After ARE, the patient's DAT results were negative and he was discharged without demonstrating symptoms of hemolysis. This case illustrates the use of ARE to limit hemolysis and prevent symptoms of a DHTR.

Abstract 318: Determinants of Red Blood Cell Omega-3-Fatty Acid Content in Patients With Peripheral Arterial Disease

2014 ◽  
Vol 34 (suppl_1) ◽  
Author(s):  
Emily V Nosova ◽  
Christopher D Owens ◽  
Karen C Chong ◽  
Hugh F Alley ◽  
Michael S Conte ◽  
...  
Keyword(s):  
Cardiovascular Risk ◽  
Peripheral Arterial Disease ◽  
Blood Cell ◽  
Fish Oil ◽  
Red Blood Cell ◽  
Arterial Disease ◽  
Omega 3 ◽  
History Of ◽  
The Mean ◽  
Peripheral Arterial

Objectives: Despite available medical therapies, patients with peripheral arterial disease (PAD) remain at high risk for cardiovascular events. n-3 polyunsaturated fatty acids (PUFAs), derived from marine sources, have been shown to improve cardiovascular mortality. The omega-3 index (O3I), a proportion of the n-3 PUFAs eicosapentanoic acid and docosahexanoic acid in the red blood cell membrane, correlates with cardiovascular risk. We sought to determine the clinical factors associated with the O3I in patients with PAD. Methods: This cross-sectional study included 111 patients, who had an ankle-brachial index of < 0.9 associated with claudication symptoms. We used linear regression to determine the association between demographic and lifestyle factors and the O3I. Results: The mean age of the cohort was 69 ± 8 years, 37% had diabetes mellitus (Hemoglobin A1c: 7 ± 1%), and 94% had smoked. The mean O3I was 5 ± 2%. Table 1 shows the variables associated with O3I in regression analyses. In a multivariate model, an independent association was maintained with increasing age, BMI, and a history of smoking and fish oil intake. Conclusions: In a cohort of patients with PAD, older age, elevated BMI, and prior fish oil supplementation predicted a higher O3I. A history of smoking correlated with a lower O3I. Our findings suggest that targeting nutrition and tobacco use with therapeutic interventions has potential to reduce cardiovascular risk among PAD patients.

scholarly journals IV. On the structure of the red blood-corpuscle of oviparous vertebrata

1869 ◽  
Vol 17 ◽  
pp. 346-350
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
The Other ◽  
Red Cell ◽  
Blood Corpuscle ◽  
Fundamental Distinction ◽  
Long Time ◽  
History Of

The red blood-cell has been perhaps more frequently and fully examined than any other animal structure; certainly none has evoked such various and even contradictory opinions of its nature. But without attempting here any history of these, it may be shortly said that amongst the conclusions now, and for a long time past, generally accepted, a chief one is that a fundamental distinction exists between the red corpuscle of Mammalia and that of the other vertebrate classes—that the red cell of the oviparous vertebrata possesses a nucleus which is not to be found in the corpuscle of the other class. This great distinction between the classes has of late years been over and over again laid down in the strongest and most unqualified terms. But I venture to ask for a still further examination of this important subject.

scholarly journals Study of Frequency and Characteristics of Red Blood Cell Alloimmunization in Thalassemic Patients: Multicenter Study from Palestine

2019 ◽  
Vol 2019 ◽  
pp. 1-5
Author(s):  
Adham Abu Taha ◽  
Ahmad Yaseen ◽  
Sa’d Suleiman ◽  
Omar Abu Zenah ◽  
Hammam Ali ◽  
...  
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Blood Transfusions ◽  
Antibody Screening ◽  
Multicenter Observational Study ◽  
Screening And Identification ◽  
History Of ◽  
Gel Technique ◽  
Prospective Multicenter Observational Study ◽  
Rbc Transfusion

Background. β-Thalassemia is a common inherited hemolytic disorder in Palestine. Red blood cell (RBC) transfusion is the principal treatment but it may cause RBC alloimmunization. This study was conducted to determine the prevalence and characteristics of RBC alloimmunization among thalassemic patients in northern governorates of Palestine. Methods. A prospective multicenter observational study was conducted in the thalassemia transfusion centers in the northern governorates of Palestine. The study included 215 thalassemia patients who received regular blood transfusions. Clinical and transfusion records of patients were examined. Antibody screening and identification was conducted using the microcolum gel technique. Results. Two hundred fifteen patients were included in the study. More than half (52.1%) of the patients were males. The median age of patients was 18 years (range: 12–24 years). The most frequent blood group was A (40.5%). Alloantibodies were detected in 12.6% of patients. Anti-D (33.3%), anti-K (25.9%) and anti-E (14.8%) were the most commonly isolated antibodies. There was no association between age, sex, starting age of transfusion, number of transfused units, history of splenectomy and alloimmunization. Conclusions. Anti-Rh and anti-K antibodies were common among this cohort of patients. Age, sex, starting age of transfusion, number of transfused units, and history of splenectomy could not predict the occurrence of alloimmunization.

scholarly journals A Case of Babesiosis in a Pregnant Patient Treated with Red Blood Cell Exchange Transfusion

2019 ◽  
Vol 2019 ◽  
pp. 1-4
Author(s):  
Baruch Abittan ◽  
Aaron Nizam ◽  
Michael Oey ◽  
Felicia Callan ◽  
Lisa Simmonds ◽  
...  
Keyword(s):  
United States ◽  
Blood Cell ◽  
Gestational Age ◽  
Red Blood Cell ◽  
Exchange Transfusion ◽  
Pregnant Patient ◽  
Babesia Microti ◽  
History Of ◽  
Safe Treatment Option ◽  
In Pregnancy

Babesiosis, caused predominantly by Babesia microti, is an emerging health risk in the Northeastern and Midwestern United States. We present a case of a pregnant woman with history of splenectomy diagnosed with babesiosis at 23 5/7 weeks of gestational age refractory to antimicrobial therapy. She underwent the first reported red blood cell exchange transfusion for babesiosis in pregnancy, at 24 4/7 weeks of gestational age, which resulted in resolution of parasitemia. She had a full term, uncomplicated cesarean delivery. Exchange transfusion is potentially a safe treatment option for severe babesiosis infection in pregnancy and should be considered when other methods are poorly tolerated or ineffective.

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