Investigation of staining, polarization and fluorescence-microscopic properties of pseudo-elastic fibres in the renal arterial system

SummaryThe mechanisms underlying clinical abnormalities associated with the antiphospholipid antibody syndrome (APAS) have not been elucidated. We measured plasma levels of lipoprotein(a) [Lp(a)], the active form of plasminogen activator inhibitor (active PAI), thrombin-antithrombin III complex (TAT) and soluble thrombomodulin (TM), to investigate the relationship of these factors to thrombotic events in APAS. Mean plasma levels of Lp(a), TAT, active PAI and TM were all significantly higher in patients with aPL than in a control group of subjects. Plasma levels of Lp(a) and active PAI were significantly higher in patients with aPL and arterial thromboses than in patients with aPL but only venous thromboses. There was a significant correlation between plasma levels of Lp(a) and active PAI in patients with aPL. These findings suggest that patients with aPL are in hypercoagulable state. High levels of Lp(a) in plasma may impair the fibrinolytic system resulting in thromboses, especially in the arterial system.

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3D modeling of the vascular system

Journal of Theoretical and Applied Vascular Research ◽

10.24019/jtavr.8 ◽

2016 ◽

Vol 1 (1) ◽

pp. 51-58 ◽

Cited By ~ 1

Author(s):

Jean François Uhl ◽

Maxime Chahim ◽

François Cros ◽

Amina Ouchene ◽

◽

...

Keyword(s):

Augmented Reality ◽

3D Modeling ◽

Vascular System ◽

Arterial System ◽

Chronic Venous Disease ◽

Venous Disease ◽

Software Products ◽

Operative Planning ◽

Morphological Modeling ◽

Pre Treatment

The 3D modeling of the vascular system could be achieved in different ways: In the venous location, the morphological modeling by MSCT venography is used to image the venous system: this morphological modeling tool accurately investigates the 3D morphology of the venous network of our patients with chronic venous disease. It is also a fine educational tool for students who learn venous anatomy, the most complex of the human body. Another kind of modeling (mathematical modeling) is used to simulate the venous functions, and virtually tests the efficacy of any proposed treatments. To image the arterial system, the aim of 3D modeling is to precisely assess and quantify the arterial morphology. The use of augmented reality before an endovascular procedure allows pre-treatment simulation, assisting in pre-operative planning as well as surgical training. In the special field of liver surgery, several 3D modeling software products are available for computer simulations and training purposes and augmented reality.

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The Arterial System in Hypertension

Hypertension ◽

10.1161/01.hyp.26.1.10 ◽

1995 ◽

Vol 26 (1) ◽

pp. 10-14 ◽

Cited By ~ 60

Author(s):

Michel E. Safar ◽

Edward D. Frohlich

Keyword(s):

Arterial System

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Role of CEUS in Vascular Pathology

Ultraschall in der Medizin - European Journal of Ultrasound ◽

10.1055/a-1403-2400 ◽

2021 ◽

Author(s):

Vito Cantisani ◽

Nicola Di Leo ◽

Emanuele David ◽

Dirk-André Clevert

Keyword(s):

Research Field ◽

Arterial System ◽

Qualitative Assessment ◽

Vascular Pathology ◽

New Horizons ◽

Contrast Enhanced ◽

Inflammatory Infiltrates ◽

Time Evaluation

AbstractIn recent years, the implementation of contrast-enhanced ultrasound (CEUS) in clinical practice has opened new horizons in the arterial pathologies research field, since this technique is able to supply new sets of data that can be crucial in patient management. The main applications of CEUS in the arterial system are the detection, characterization, and follow-up of carotid plaques and endoleaks after EVAR. Other situations in which CEUS was demonstrated to be a useful tool are large vessel vasculitis, dissections, and untreated aneurysms. In carotid atherosclerosis CEUS is not only able to acquire quantitative data about stenosis but also to perform a qualitative assessment of the plaque. The most important plaque features that CEUS is able to depict are ulceration, neovascularization, and the presence of inflammatory infiltrates. All of these factors contribute to plaque vulnerability. Thus, CEUS is crucial in order to allow better risk stratification and management of patients. In follow-up after EVAR, CEUS shows sensitivity and specificity values similar to CTA while ensuring several advantages, such as lower cost and the absence of ionizing radiation and nephrotoxic agents. Moreover, CEUS is able to offer real-time evaluation of endoleaks and thus is a useful tool in cases that are ambiguous on CTA. Most limitations are patient-related and are the same as in all other ultrasound techniques, such as high BMI and meteorism.

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Prediction of 3D Cardiovascular hemodynamics before and after coronary artery bypass surgery via deep learning

Communications Biology ◽

10.1038/s42003-020-01638-1 ◽

2021 ◽

Vol 4 (1) ◽

Author(s):

Gaoyang Li ◽

Haoran Wang ◽

Mingzi Zhang ◽

Simon Tupin ◽

Aike Qiao ◽

...

Keyword(s):

Deep Learning ◽

Artery Bypass ◽

Computational Cost ◽

Specific Model ◽

Arterial System ◽

Patient Specific ◽

Cardiovascular Hemodynamics ◽

Before And After ◽

Deep Learning Network ◽

Cfd Method

AbstractThe clinical treatment planning of coronary heart disease requires hemodynamic parameters to provide proper guidance. Computational fluid dynamics (CFD) is gradually used in the simulation of cardiovascular hemodynamics. However, for the patient-specific model, the complex operation and high computational cost of CFD hinder its clinical application. To deal with these problems, we develop cardiovascular hemodynamic point datasets and a dual sampling channel deep learning network, which can analyze and reproduce the relationship between the cardiovascular geometry and internal hemodynamics. The statistical analysis shows that the hemodynamic prediction results of deep learning are in agreement with the conventional CFD method, but the calculation time is reduced 600-fold. In terms of over 2 million nodes, prediction accuracy of around 90%, computational efficiency to predict cardiovascular hemodynamics within 1 second, and universality for evaluating complex arterial system, our deep learning method can meet the needs of most situations.

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A square-pulse flow method for measuring characteristics of the arterial bed

Journal of Applied Physiology ◽

10.1152/jappl.1976.40.3.425 ◽

1976 ◽

Vol 40 (3) ◽

pp. 425-433 ◽

Cited By ~ 3

Author(s):

M. G. Bottomley ◽

G. W. Mainwood

Keyword(s):

Arterial Compliance ◽

Peripheral Resistance ◽

Mean Value ◽

Pressure Response ◽

Arterial System ◽

Response Curves ◽

Arterial Tree ◽

Pulse Flow ◽

Critical Closing Pressure ◽

Closing Pressure

A device was designed to provide a “square” pulse of blood flow into the arterial system. Pulses were injected into the carotid artery of the rabbit during transient cardiac arrest. Analysis of pressure response curves generated by the flow provides information as to the state of the arterial tree. With certain assumptions it is possible to estimate from these curves lumped values of peripheral resistance, critical closing pressure, and arterial compliance. In a series of 12 rabbits the mean value of peripheral resistance was found to be 0.21 +/- 0.7 mmHg-ml-1-min and critical closing pressure was estimated to be 23.6 +/- 3.8 mmHg. This method gives two possible values for arterial compliance 0.036 +/- 0.010 and 0.055 +/- 0.010 ml-mm-1 based, respectively, on the rise and decay curves of the pressure response. The theory and limitations of the method are discussed. The use of the method is illustrated in following the response to increased PCO2 and hemorrhage.

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Uretero-Iliac artery fistula: a rare cause of haematuria

BMJ Case Reports ◽

10.1136/bcr-2019-232189 ◽

2020 ◽

Vol 13 (9) ◽

pp. e232189

Author(s):

Natalia Hernandez ◽

Bethany Desroches ◽

Eric Peden ◽

Raj Satkunasivam

Keyword(s):

Iliac Artery ◽

Percutaneous Nephrostomy ◽

Arterial System ◽

Endoscopic Evaluation ◽

Stent Removal ◽

Retrograde Pyelogram ◽

History Of ◽

Gross Haematuria ◽

Multiple Episodes

A woman in her mid-forties with a history of cervical cancer requiring chemoradiation presented with bilateral ureteral strictures secondary to radiation therapy. The ureteral obstruction was initially relieved with bilateral percutaneous nephrostomy tubes, and subsequently, bilateral ureteral stents. Over the course of 8 months, she presented with multiple episodes of severe gross haematuria. This persisted even after stent removal and conversion back to percutaneous nephrostomy tubes. The initial evaluation, done with concern for an uretero-iliac artery fistula, which included bilateral retrograde pyelograms and CT angiography was non-diagnostic. Given continued haematuria, repeat endoscopic evaluation was undertaken; on retrograde pyelogram, brisk contrast was seen to pass into the arterial system, consistent with a left ureteroarterial fistula. The patient underwent endovascular iliac artery stent placement. Subsequently, the patient underwent resection of the iliac artery with endovascular graft in situ, left distal ureterectomy with proximal ureteral ligation following femoral-to-femoral bypass. This allowed for complete resolution of the patient’s gross haematuria episodes.

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