Specific interaction of IgE antibodies with a carbohydrate epitope of honey bee venom phospholipase A2

Allergy ◽  
1987 ◽  
Vol 42 (6) ◽  
pp. 464-470 ◽  
Author(s):  
A. Weber ◽  
H. Schröder ◽  
K. Thalberg ◽  
L. Marz
Keyword(s):  
Phospholipase A2 ◽  
Honey Bee ◽  
Specific Interaction ◽  
Bee Venom ◽  
Ige Antibodies ◽  
Carbohydrate Epitope

The glycoprotein nature of phospholipase A2, hyaluronidase and acid phosphatase from honey-bee venom

Toxicon ◽  
1983 ◽  
Vol 21 (6) ◽  
pp. 893-896 ◽  
Author(s):  
Leopold März ◽  
Christian Kühne ◽  
Heribert Michl
Keyword(s):  
Acid Phosphatase ◽  
Phospholipase A2 ◽  
Honey Bee ◽  
Bee Venom

scholarly journals Phospholipase A2 enzyme from the venom of Egyptian honey bee Apis mellifera lamarckii with anti-platelet aggregation and anti-coagulation activities

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Doaa A. Darwish ◽  
Hassan M. M. Masoud ◽  
Mohamed M. Abdel-Monsef ◽  
Mohamed S. Helmy ◽  
Hind A. Zidan ◽  
...  
Keyword(s):  
Apis Mellifera ◽  
Platelet Aggregation ◽  
Phospholipase A2 ◽  
Honey Bee ◽  
Specific Activity ◽  
Deae Cellulose ◽  
High Specific Activity ◽  
Inhibitory Effect ◽  
Bee Venom ◽  
Very High

Abstract Background Honey bee venom contains various enzymes with wide medical and pharmaceutical applications. Results The phospholipase A2 (PLA2) has been apparently purified from the venom of Egyptian honey bee (Apis mellifera lamarckii) 8.9-fold to a very high specific activity of 6033 U/mg protein using DEAE–cellulose and Sephacryl S-300 columns. The purified bee venom PLA2 is monomeric 16 kDa protein and has isoelectric point (pI) of 5.9. The optimal activity of bee venom PLA2 was attained at pH 8 and 45 °C. Cu2+, Ni2+, Fe2+, Ca2+, and Co2+ exhibited a complete activating effect on it, while Zn2+, Mn2+, NaN3, PMSF, N-Methylmaleimide, and EDTA have inhibitory effect. Conclusions The purified bee venom PLA2 exhibited anti-platelet aggregation and anti-coagulation activities which makes it promising agent for developing novel anti-clot formation drugs in future.

240 IgG1, IgG4 and IgE antibodies anti honey bee venom produced during honey bee venom immunotherapy

1991 ◽  
Vol 87 (1) ◽  
pp. 198
Author(s):  
O ROMERO ◽  
G BUSTOSJR ◽  
G BUSTOS ◽  
M AZAR ◽  
G BUSTOS
Keyword(s):  
Honey Bee ◽  
Bee Venom ◽  
Venom Immunotherapy ◽  
Ige Antibodies

scholarly journals Beehive Products as Antibacterial Agents: A Review

Antibiotics ◽  
2021 ◽  
Vol 10 (6) ◽  
pp. 717
Author(s):  
Rita Abou Nader ◽  
Rawan Mackieh ◽  
Rim Wehbe ◽  
Dany El El Obeid ◽  
Jean Marc Sabatier ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Honey Bee ◽  
Antibacterial Agents ◽  
Royal Jelly ◽  
Biological Activities ◽  
Vital Role ◽  
Bee Venom ◽  
Bacterial Strains ◽  
Wide Range ◽  
Life Threatening

Honeybees are one of the most marvelous and economically beneficial insects. As pollinators, they play a vital role in every aspect of the ecosystem. Beehive products have been used for thousands of years in many cultures for the treatment of various diseases. Their healing properties have been documented in many religious texts like the Noble Quran and the Holy Bible. Honey, bee venom, propolis, pollen and royal jelly all demonstrated a richness in their bioactive compounds which make them effective against a variety of bacterial strains. Furthermore, many studies showed that honey and bee venom work as powerful antibacterial agents against a wide range of bacteria including life-threatening bacteria. Several reports documented the biological activities of honeybee products but none of them emphasized on the antibacterial activity of all beehive products. Therefore, this review aims to highlight the antibacterial activity of honey, bee venom, propolis, pollen and royal jelly, that are produced by honeybees.

Sign in / Sign up

Export Citation Format

Share Document